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Causally interpretable meta-analysis combines information from a collection of randomized controlled trials to estimate treatment effects in a target population in which experimentation may not be possible but covariate information can be…

Methodology · Statistics 2022-05-03 Jon A. Steingrimsson , David H. Barker , Ruofan Bie , Issa J. Dahabreh

This article focuses on measurement error in covariates in regression analyses in which the aim is to estimate the association between one or more covariates and an outcome, adjusting for confounding. Error in covariate measurements, if…

Methodology · Statistics 2019-10-16 Ruth H. Keogh , Jonathan W. Bartlett

Significant progress has been made in developing identification and estimation techniques for missing data problems where modeling assumptions can be described via a directed acyclic graph. The validity of results using such techniques rely…

Methodology · Statistics 2023-06-13 Razieh Nabi , Rohit Bhattacharya

Causal analysis may be affected by selection bias, which is defined as the systematic exclusion of data from a certain subpopulation. Previous work in this area focused on the derivation of identifiability conditions. We propose instead a…

Machine Learning · Statistics 2022-08-03 Marco Zaffalon , Alessandro Antonucci , Rafael Cabañas , David Huber , Dario Azzimonti

We consider the problem of assessing whether, in an individual case, there is a causal relationship between an observed exposure and a response variable. When data are available on similar individuals we may be able to estimate prospective…

Statistics Theory · Mathematics 2023-11-15 Monica Musio , Philip Dawid

Two major ideas in the analysis of missing data are (a) the EM algorithm [Dempster, Laird and Rubin, J. Roy. Statist. Soc. Ser. B 39 (1977) 1--38] for maximum likelihood (ML) estimation, and (b) the formulation of models for the joint…

Methodology · Statistics 2011-04-14 Yan Zhou , Roderick J. A. Little , John D. Kalbfleisch

Multivariate density estimation is a popular technique in statistics with wide applications including regression models allowing for heteroskedasticity in conditional variances. The estimation problems become more challenging when…

Methodology · Statistics 2018-08-15 Zhen Li , Lili Wu , Weilian Zhou , Sujit Ghosh

Bayesian hypothesis testing is re-examined from the perspective of an a priori assessment of the test statistic distribution under the alternative. By assessing the distribution of an observable test statistic, rather than prior parameter…

Statistics Theory · Mathematics 2018-08-28 Hedibert F. Lopes , Nicholas G. Polson

Causal inference relies on the untestable assumption of no unmeasured confounding. Sensitivity analysis can be used to quantify the impact of unmeasured confounding on causal estimates. Among sensitivity analysis methods proposed in the…

Methodology · Statistics 2026-03-12 Yushu Zou , Liangyuan Hu , Amanda Ricciuto , Mark Deneau , Kuan Liu

Data exhibiting heavy-tails in one or more dimensions is often studied using the framework of regular variation. In a multivariate setting this requires identifying specific forms of dependence in the data; this means identifying that the…

Statistics Theory · Mathematics 2017-02-02 Bikramjit Das , Sidney I. Resnick

Can instrumental variables be found from data? While instrumental variable (IV) methods are widely used to identify causal effect, testing their validity from observed data remains a challenge. This is because validity of an IV depends on…

Methodology · Statistics 2018-12-05 Amit Sharma

Large-scale population-level datasets, such as the UK Biobank and the All of Us Research Program, often lack covariates needed for a specific analysis, such as genetic or lifestyle measures, while related studies measure them. This creates…

Methodology · Statistics 2026-05-07 Huali Zhao , Tianying Wang

Handling missing data in time series is a complex problem due to the presence of temporal dependence. General-purpose imputation methods, while widely used, often distort key statistical properties of the data, such as variance and…

Methodology · Statistics 2026-03-18 Guilherme Pumi , Taiane Schaedler Prass , Douglas Krauthein Verdum

We propose a procedure for imputing missing values of time-dependent covariates in a survival model using fully conditional specification. Specifically, we focus on imputing missing values of a longitudinal marker in joint modeling of the…

Methodology · Statistics 2024-03-29 Havi Murad , Nirit Agay , Rachel Dankner

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of…

Methodology · Statistics 2026-05-18 X. M. Kavelaars , S. van Buuren , J. R. van Ginkel

Monotone missingness is commonly encountered in practice when a missing measurement compels another measurement to be missing. Because of the simpler missing data pattern, monotone missing data is often viewed as beneficial from the…

Methodology · Statistics 2025-11-14 Santtu Tikka , Juha Karvanen

We develop simple methods for constructing likelihoods and parameter priors for learning about the parameters and structure of a Bayesian network. In particular, we introduce several assumptions that permit the construction of likelihoods…

Machine Learning · Computer Science 2021-07-01 David Heckerman , Dan Geiger

We study a class of missingness mechanisms, called sequentially additive nonignorable, for modeling multivariate data with item nonresponse. These mechanisms explicitly allow the probability of nonresponse for each variable to depend on the…

Methodology · Statistics 2019-02-19 Mauricio Sadinle , Jerome P. Reiter

Bayesian inference is often utilized for uncertainty quantification tasks. A recent analysis by Xu and Raginsky 2022 rigorously decomposed the predictive uncertainty in Bayesian inference into two uncertainties, called aleatoric and…

Machine Learning · Statistics 2023-07-25 Futoshi Futami , Tomoharu Iwata

In designed experiments and surveys, known laws or design feat ures provide checks on the most relevant aspects of a model and identify the target parameters. In contrast, in most observational studies in the health and social sciences, the…

Methodology · Statistics 2010-01-18 Sander Greenland