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Assessment of replicability is critical to ensure the quality and rigor of scientific research. In this paper, we discuss inference and modeling principles for replicability assessment. Targeting distinct application scenarios, we propose…

Methodology · Statistics 2021-05-11 Yi Zhao , Xiaoquan Wen

Meta-analysis is an important tool for combining results from multiple studies and has been widely used in evidence-based medicine for several decades. This paper reports, for the first time, an interesting and valuable paradox in…

Applications · Statistics 2019-05-15 Jiandong Shi , Aimin Wu , Tiejun Tong

Among plausible causes for replicability failure, one that has not received sufficient attention is the environment in which the research is conducted. Consisting of the population, equipment, personnel, and various conditions such as…

Methodology · Statistics 2020-09-01 James J. Higgins , Michael J. Higgins , Jinguang Lin

The replicability crisis in the social, behavioral, and data sciences has led to the formulation of algorithm frameworks for replicability -- i.e., a requirement that an algorithm produce identical outputs (with high probability) when run…

Machine Learning · Computer Science 2023-11-01 Eric Eaton , Marcel Hussing , Michael Kearns , Jessica Sorrell

Memorization in language models is typically treated as a homogenous phenomenon, neglecting the specifics of the memorized data. We instead model memorization as the effect of a set of complex factors that describe each sample and relate it…

Replicability analysis aims to identify the findings that replicated across independent studies that examine the same features. We provide powerful novel replicability analysis procedures for two studies for FWER and for FDR control on the…

Methodology · Statistics 2019-03-01 Marina Bogomolov , Ruth Heller

Rapid advances in computing technology over the past few decades have spurred two extraordinary phenomena in science: large-scale and high-throughput data collection coupled with the creation and implementation of complex statistical…

Other Statistics · Statistics 2020-07-27 Roger D. Peng , Stephanie C. Hicks

Why are some research studies easy to reproduce while others are difficult? Casting doubt on the accuracy of scientific work is not fruitful, especially when an individual researcher cannot reproduce the claims made in the paper. There…

Digital Libraries · Computer Science 2023-08-25 Akhil Pandey Akella , David Koop , Hamed Alhoori

We conduct a review to assess how the simulation of repeated or recurrent events are planned. For such multivariate time-to-events, it is well established that the underlying mechanism is likely to be complex and to involve in particular…

Applications · Statistics 2015-03-20 Juliette Pénichoux , Thierry Moreau , Aurélien Latouche

Reproducibility has been increasingly encouraged by communities of science in order to validate experimental conclusions, and replication studies represent a significant opportunity to vision scientists wishing contribute new perceptual…

Human-Computer Interaction · Computer Science 2019-08-26 Ghulam Jilani Quadri , Paul Rosen

Results of simulation studies evaluating the performance of statistical methods are often considered actionable and thus can have a major impact on the way empirical research is implemented. However, so far there is limited evidence about…

Reproducibility is a major concern across scientific fields. Human-Computer Interaction (HCI), in particular, is subject to diverse reproducibility challenges due to the wide range of research methodologies employed. In this article, we…

Human-Computer Interaction · Computer Science 2024-11-04 Thomas Kosch , Sebastian Feger

Replication of experimental results has been a challenge faced by many scientific disciplines, including the field of machine learning. Recent work on the theory of machine learning has formalized replicability as the demand that an…

Machine Learning · Computer Science 2026-04-15 Eric Eaton , Marcel Hussing , Michael Kearns , Aaron Roth , Sikata Bela Sengupta , Jessica Sorrell

Fixed effects models are very flexible because they do not make assumptions on the distribution of effects and can also be used if the heterogeneity component is correlated with explanatory variables. A disadvantage is the large number of…

Methodology · Statistics 2015-12-17 Moritz Berger , Gerhard Tutz

Recent studies have shown that the majority of published computational models in systems biology and physiology are not repeatable or reproducible. There are a variety of reasons for this. One of the most likely reasons is that given how…

Other Quantitative Biology · Quantitative Biology 2021-07-13 Herbert M. Sauro

While extensive guidance exists for ensuring the reproducibility of one's own study, there is little discussion regarding the reproduction and replication of external studies within one's own research. To initiate this discussion, drawing…

Machine Learning · Computer Science 2024-01-10 Milton S. Gomez , Tom Beucler

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

Scientific knowledge discovery increasingly relies on large language models, yet many existing scholarly assistants depend on proprietary systems with tens or hundreds of billions of parameters. Such reliance limits reproducibility and…

Information Retrieval · Computer Science 2026-04-23 Florian Kelber , Matthias Jobst , Yuni Susanti , Michael Färber

Reproducibility is central to the credibility of scientific findings, yet complete replication studies are costly and infrequent. However, many biological experiments contain internal replication, which is defined as repetition across…

Applications · Statistics 2025-06-05 Stanley E. Lazic

The reproducibility crisis has led to an increasing number of replication studies being conducted. Sample sizes for replication studies are often calculated using conditional power based on the effect estimate from the original study.…

Methodology · Statistics 2022-10-19 Charlotte Micheloud , Leonhard Held