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Spiking Neural Networks (SNNs) exhibit exceptional energy efficiency on neuromorphic hardware due to their sparse activation patterns. However, conventional training methods based on surrogate gradients and Backpropagation Through Time…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Xiaochen Zhao , Chengting Yu , Kairong Yu , Lei Liu , Aili Wang

Blood pressure monitoring is an essential component of hypertension management and in the prediction of associated comorbidities. Blood pressure is a dynamic vital sign with frequent changes throughout a given day. Capturing blood pressure…

Machine Learning · Computer Science 2020-07-29 Lida Zhang , Nathan C. Hurley , Bassem Ibrahim , Erica Spatz , Harlan M. Krumholz , Roozbeh Jafari , Bobak J. Mortazavi

We develop a knowledge-based automated planning (KBAP) pipeline that generates treatment plans using deep neural network architectures for predicting 3D doses. Our pipeline consisted of a generative adversarial network (GAN) to predict dose…

Medical Physics · Physics 2018-12-24 Aaron Babier , Rafid Mahmood , Andrea L. McNiven , Adam Diamant , Timothy C. Y. Chan

Recent years have witnessed Spiking Neural Networks (SNNs) gaining attention for their ultra-low energy consumption and high biological plausibility compared with traditional Artificial Neural Networks (ANNs). Despite their distinguished…

Neural and Evolutionary Computing · Computer Science 2024-08-30 Jiahang Cao , Hanzhong Guo , Ziqing Wang , Deming Zhou , Hao Cheng , Qiang Zhang , Renjing Xu

Purpose: To develop a knowledge-based voxel-wise dose prediction system using a convolution neural network for high-dose-rate brachytherapy cervical cancer treatments with a tandem-and-ovoid (T&O) applicator. Methods: A 3D U-NET was…

Purpose The purpose of this study was to develop and evaluate a deep neural network (DNN) capable of generating flat-panel detector (FPD) images from digitally reconstructed radiography (DRR) images in lung cancer treatment, with the aim of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Chisako Hayashi , Shinichiro Mori , Yasukuni Mori , Lim Taehyeung , Hiroki Suyari , Hitoshi Ishikawa

This paper introduces a novel approach to Dynamic Artificial Neural Networks (D-ANNs) for multi-task demand forecasting called Neuroplastic Multi-Task Network (NMT-Net). Unlike conventional methods focusing on inference-time dynamics or…

Artificial Intelligence · Computer Science 2025-09-30 Mateusz Żarski , Sławomir Nowaczyk

In this work, we have investigated the sensitivity of the effectiveness (TCP) of molecular radiotherapy (MRT) treatment to uncertainties of the dose rate curves that may appear when reconstructing those curves. We generated different dose…

Medical Physics · Physics 2025-02-03 Pedro Otero-Casal , Aldán Baliño , Sara Neira , Faustino Gómez , Juan Pardo-Montero

An important aspect in the development of small molecules as drugs or agro-chemicals is their systemic availability after intravenous and oral administration. The prediction of the systemic availability from the chemical structure of a…

Quantitative Methods · Quantitative Biology 2024-01-03 Florian Führer , Andrea Gruber , Holger Diedam , Andreas H. Göller , Stephan Menz , Sebastian Schneckener

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

Human-Computer Interaction · Computer Science 2023-09-28 Carla Floricel , Andrew Wentzel , Abdallah Mohamed , C. David Fuller , Guadalupe Canahuate , G. Elisabeta Marai

Distant metastases (DM) refer to the dissemination of tumors, usually, beyond the organ where the tumor originated. They are the leading cause of death in patients with soft-tissue sarcomas (STSs). Positron emission tomography-computed…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Yige Peng , Lei Bi , Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

An individualized dose rule recommends a dose level within a continuous safe dose range based on patient level information such as physical conditions, genetic factors and medication histories. Traditionally, personalized dose finding…

Methodology · Statistics 2020-07-21 Liangyu Zhu , Wenbin Lu , Michael R. Kosorok , Rui Song

Stereotactic radiotherapy (SRT) is one of the most important treatment for patients with brain metastases (BM). Conventionally, following SRT patients are monitored by serial imaging and receive salvage treatments in case of significant…

Computer Vision and Pattern Recognition · Computer Science 2023-02-20 Philipp Sommer , Yixing Huang , Christoph Bert , Andreas Maier , Manuel Schmidt , Arnd Dörfler , Rainer Fietkau , Florian Putz

Several machine learning techniques for accurate detection of skin cancer from medical images have been reported. Many of these techniques are based on pre-trained convolutional neural networks (CNNs), which enable training the models based…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Aqsa Saeed Qureshi , Teemu Roos

Purpose: Prior AI-based dose prediction studies in photon and proton therapy often neglect underlying physics, limiting their generalizability to handle outlier clinical cases, especially for pencil beam scanning proton therapy (PBSPT). Our…

A permanently increasing number of on-board automotive control systems requires new approaches to their digital mapping that improves functionality in terms of adaptability and robustness as well as enables their easier on-line software…

Systems and Control · Electrical Eng. & Systems 2022-07-20 Moritz Zink , Martin Schiele , Valentin Ivanov

Automation of brain tumor segmentation in 3D magnetic resonance images (MRIs) is key to assess the diagnostic and treatment of the disease. In recent years, convolutional neural networks (CNNs) have shown improved results in the task.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-01 Laura Mora Ballestar , Veronica Vilaplana

Many state-of-the-art algorithms for solving hard combinatorial problems in artificial intelligence (AI) include elements of stochasticity that lead to high variations in runtime, even for a fixed problem instance. Knowledge about the…

Artificial Intelligence · Computer Science 2018-07-10 Katharina Eggensperger , Marius Lindauer , Frank Hutter

Treatment planning system calculations in inhomogeneous regions may present significant inaccuracies due to loss of electronic equilibrium. In this study, three different dose calculation algorithms, pencil beam, collapsed cone, and…

Medical Physics · Physics 2015-03-12 Sung Jin Kim , Dong Ho Kim , Sung Kyu Kim

Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…

Medical Physics · Physics 2018-03-05 Simona Giordanengo , Marco Donetti