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Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

Diabetic retinopathy (DR) is the most common form of diabetic eye disease. Retinopathy can affect all diabetic patients and becomes particularly dangerous, increasing the risk of blindness, if it is left untreated. The success rate of its…

Computer Vision and Pattern Recognition · Computer Science 2019-02-11 Oindrila Saha , Rachana Sathish , Debdoot Sheet

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Eye diseases are common in older Americans and can lead to decreased vision and blindness. Recent advancements in imaging technologies allow clinicians to capture high-quality images of the retinal blood vessels via Optical Coherence…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Jacob Thrasher , Annahita Amireskandari , Prashnna Gyawali

Optical coherence tomography (OCT) and confocal microscopy are pivotal in retinal imaging, offering distinct advantages and limitations. In vivo OCT offers rapid, non-invasive imaging but can suffer from clarity issues and motion artifacts,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Xin Tian , Nantheera Anantrasirichai , Lindsay Nicholson , Alin Achim

Given the capacity of Optical Coherence Tomography (OCT) imaging to display symptoms of a wide variety of eye diseases and neurological disorders, the need for OCT image segmentation and the corresponding data interpretation is latterly…

Optical coherence tomography angiography (OCTA) is a novel non-invasive imaging modality that allows micron-level resolution to visualize the retinal microvasculature. The retinal vessel segmentation in OCTA images is still an open problem,…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Mingchao Li , Yerui Chen , Weiwei Zhang , Qiang Chen

30 million Optical Coherence Tomography (OCT) imaging tests are issued annually to diagnose various retinal diseases, but accurate diagnosis of OCT scans requires trained eye care professionals who are still prone to making errors. With…

Image and Video Processing · Electrical Eng. & Systems 2022-10-04 Evan Wen , Rebecca Sorenson , Max Ehrlich

3D imaging modalities are becoming increasingly popular and relevant in retinal imaging owing to their effectiveness in highlighting structures in sub-retinal layers. OCT is one such modality which has great importance in the context of…

Computer Vision and Pattern Recognition · Computer Science 2016-12-09 Karthik Gopinath , Jayanthi Sivaswamy

In medical science, the use of computer science in disease detection and diagnosis is gaining popularity. Previously, the detection of disease used to take a significant amount of time and was less reliable. Machine learning (ML) techniques…

Image and Video Processing · Electrical Eng. & Systems 2019-12-18 Nowshin Tasnim , Mahmudul Hasan , Ishrak Islam

This paper presents a novel automated system that segments six sub-retinal layers from optical coherence tomography (OCT) image stacks of healthy patients and patients with diabetic macular edema (DME). First, each image in the OCT stack is…

Computer Vision and Pattern Recognition · Computer Science 2016-10-25 Sohini Roychowdhury , Dara D. Koozekanani , Michael Reinsbach , Keshab K. Parhi

Retinal imaging serves as a valuable tool for diagnosis of various diseases. However, reading retinal images is a difficult and time-consuming task even for experienced specialists. The fundamental step towards automated retinal image…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Liangzhi Li , Manisha Verma , Yuta Nakashima , Ryo Kawasaki , Hajime Nagahara

Segmentation of retinal vessels from retinal fundus images is the key step in the automatic retinal image analysis. In this paper, we propose a new unsupervised automatic method to segment the retinal vessels from retinal fundus images.…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Renoh Johnson Chalakkal , Waleed Abdulla

Computer vision and image processing techniques provide important assistance to physicians and relieve their workload in different tasks. In particular, identifying objects of interest such as lesions and anatomical structures from the…

Medical Physics · Physics 2020-04-23 Meysam Tavakoli , Mahdieh Nazar , Alireza Golestaneh , Faraz Kalantari

Automated detection of retinal structures, such as retinal vessels (RV), the foveal avascular zone (FAZ), and retinal vascular junctions (RVJ), are of great importance for understanding diseases of the eye and clinical decision-making. In…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Jinkui Hao , Ting Shen , Xueli Zhu , Yonghuai Liu , Ardhendu Behera , Dan Zhang , Bang Chen , Jiang Liu , Jiong Zhang , Yitian Zhao

We have developed and trained a convolutional neural network to automatically and simultaneously segment optic disc, fovea and blood vessels. Fundus images were normalised before segmentation was performed to enforce consistency in…

Computer Vision and Pattern Recognition · Computer Science 2017-02-03 Jen Hong Tan , U. Rajendra Acharya , Sulatha V. Bhandary , Kuang Chua Chua , Sobha Sivaprasad

Optical coherence tomography (OCT) captures cross-sectional data and is used for the screening, monitoring, and treatment planning of retinal diseases. Technological developments to increase the speed of acquisition often results in systems…

Image and Video Processing · Electrical Eng. & Systems 2023-01-03 Timothy T. Yu , Da Ma , Jayden Cole , Myeong Jin Ju , Mirza F. Beg , Marinko V. Sarunic

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

Optical coherence tomography (OCT) is a prevalent imaging technique for retina. However, it is affected by multiplicative speckle noise that can degrade the visibility of essential anatomical structures, including blood vessels and tissue…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Dewei Hu , Joseph D. Malone , Yigit Atay , Yuankai K. Tao , Ipek Oguz

Intracoronary Optical Coherence Tomography (OCT) enables high-resolution visualization of coronary vessel anatomy but presents challenges due to noise, imaging artifacts, and complex tissue structures. This paper proposes a fully automated…

Computer Vision and Pattern Recognition · Computer Science 2026-02-20 Amal Lahchim , Lambros Athanasiou
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