Related papers: Freeze casting of hydroxyapatite scaffolds for bon…
Starch based scaffolds are considered as promising biomaterials for bone tissue engineering. In this study, a highly porous starch/polyvinyl alcohol (PVA) based nanocomposite scaffold with a gradient pore structure was made by incorporating…
Freeze-casting produces materials with complex, three-dimensional pore structures which may be tuned during the solidification process. The range of potential applications of freeze-cast materials is vast, and includes: structural…
Materials that are strong, ultra-light weight and tough are in demand for a range of applications, requiring architectures and components carefully designed from the micrometer down to nanometer scales. Nacre-a structure found in many…
A key issue for the fabrication of scaffolds for tissue engineering is the development of processing techniques flexible enough to produce materials with a wide spectrum of solubility (bioresorption rates) and mechanical properties matching…
Freeze-casting, the templating of porous structure by the solidification of a solvent, have seen a great deal of efforts during the last few years. Of particular interest are the unique structure and properties exhibited by porous…
Energy harvesting is an important developing technology for a new generation of self-powered sensor networks. This paper demonstrates the significant improvement in the piezoelectric energy harvesting performance of barium titanate by…
Achieving an optimal biomechanical environment within bone scaffolds is critical for promoting tissue regeneration, particularly in load-bearing anatomical sites where rigid fixation can induce stress shielding and compromise healing.…
A 3-D porous apatite scaffold (B-HA), recently obtained through biomorphic transformation of a natural wood, is investigated on its multi-scale porous structure determining superior mechanical properties and biological behaviour. B-HA shows…
Additive manufacturing (AM) techniques have gained interest in the tissue engineering field thanks to their versatility and unique possibilities of producing constructs with complex macroscopic geometries and defined patterns. Recently,…
Thick honeycomb-like electrospun scaffold with nanoparticles of hydroxyapatite (nHA) recently demonstrated its potential to promote proliferation and differentiation of a murine embryonic cell line (C3H10T1/2) to osteoblasts. In order to…
The increasing demand for bone grafts due to the aging population has opened new opportunities for the manufacture of porous ceramics to assist in bone reconstruction. In our study, we investigate a new, promising method to manufacture…
Developing successful scaffolds requires clinicians to adopt a multidisciplinary approach in order to understand and stimulate the natural bone regeneration process. A variety of natural and synthetic biomaterials, including naturally…
The freezing of concentrated colloidal suspensions is a complex physical process involving a large number of parameters. These parameters provide unique tools to manipulate the architecture of freeze-cast materials at multiple length scales…
The formation of regular patterns is a common feature of many solidification processes involving cast materials. We describe here how regular patterns can be obtained in porous alumina and hydroxyapatite (HAP) by controlling the freezing of…
We present a three dimensional, time dependent model for bone regeneration in the presence of porous scaffolds to bridge critical size bone defects. Our approach uses homogenized quantities, thus drastically reducing computational cost…
Freeze casting has been increasingly applied to process various porous materials. A linear relationship between the final porosity and the initial solid material fraction in the suspension was reported by other researchers. However, the…
Silicon-substituted hydroxyapatite (SiHA) macroporous scaffolds have been prepared by robocasting. In order to optimize their bone regeneration properties, we have manufactured these scaffolds presenting different microstructures:…
Effective scaffolds for bone tissue-engineering are those that combine adequate mechanical and chemical performance with osseointegrative, angiogenetic and anti-bacterial modes of bioactivity. To address these requirements via a combined…
We consider a simple one-dimensional time-dependent model for bone regeneration in the presence of a bio-resorbable polymer scaffold. Within the framework of the model, we optimize the effective mechanical stiffness of the polymer scaffold…
The role of graphene nanowindows in the nanohydroxyapatite bone scaffold preparation is important for the preparation of mechanically robust scaffolds and implementation in bone recovery. Here, we report a graphene-nanohydroxyapatite…