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Background: Receiver Operating Characteristic (ROC) curves are widely used to evaluate the performance of Software Defect Prediction (SDP) models that estimate module fault-proneness, i.e., the probability that a module is faulty. A ROC…

Software Engineering · Computer Science 2026-04-23 Luigi Lavazza , Gabriele Rotoloni , Sandro Morasca

We discuss a shift in perspective from traditional approaches to breast cancer risk prediction: modelling families rather than individuals as unit of analysis. By investigating the latent familial risk underlying breast cancer diagnoses, we…

Applications · Statistics 2025-08-25 Maria Veronica Vinattieri , Marco Bonetti , Kamila Czene

While analysing time-to-event data, it is possible that a certain fraction of subjects will never experience the event of interest and they are said to be cured. When this feature of survival models is taken into account, the models are…

Methodology · Statistics 2020-01-27 Khandoker Akib Mohammad , Yuichi Hirose , Budhi Surya , Yuan Yao

The ROC curve is a statistical tool that analyses the accuracy of a diagnostic test in which a variable is used to decide whether an individual is healthy or not. Along with that diagnostic variable it is usual to have information of some…

The Area Under the ROC Curve (AUC) is a crucial metric for machine learning, which evaluates the average performance over all possible True Positive Rates (TPRs) and False Positive Rates (FPRs). Based on the knowledge that a skillful…

Machine Learning · Computer Science 2022-06-24 Zhiyong Yang , Qianqian Xu , Shilong Bao , Yuan He , Xiaochun Cao , Qingming Huang

Algorithms for constraint-based causal discovery select graphical causal models among a space of possible candidates (e.g., all directed acyclic graphs) by executing a sequence of conditional independence tests. These may be used to inform…

Methodology · Statistics 2025-09-19 Ting-Hsuan Chang , Zijian Guo , Daniel Malinsky

Single-parameter summaries of variable effects in regression settings are desirable for ease of interpretation. However (partially) linear models for example, which would deliver these, may fit poorly to the data. On the other hand, an…

Statistics Theory · Mathematics 2025-07-28 Harvey Klyne , Rajen D. Shah

Clinical language models (LMs) are increasingly applied to support clinical risk prediction from free-text notes, yet their uncertainty estimates often remain poorly calibrated and clinically unreliable. In this work, we propose Clinical…

Computation and Language · Computer Science 2026-04-27 Sizhe Wang , Ziqi Xu , Claire Najjuuko , Charles Alba , Chenyang Lu

In biomedical studies it is of substantial interest to develop risk prediction scores using high-dimensional data such as gene expression data for clinical endpoints that are subject to censoring. In the presence of well-established…

Applications · Statistics 2011-11-24 Qi Long , Matthias Chung , Carlos S. Moreno , Brent A. Johnson

In this paper we explore partial coherence as a tool for evaluating causal influence of one signal sequence on another. In some cases the signal sequence is sampled from a time- or space-series. The key idea is to establish a connection…

Signal Processing · Electrical Eng. & Systems 2021-12-09 Louis L. Scharf , Yuan Wang

Utilizing established risk factors and prognostic models can often improve the construction of a newer risk model that uses novel biomarkers in a smaller, internal study. However, directly borrowing information from an established…

Methodology · Statistics 2026-03-12 Nicholas C. Henderson

Time-dependent Receiver Operating Characteristics (ROC) analysis is a standard method to evaluate the discriminative performance of biomarkers or risk scores for time-to-event outcomes. Extensions of this useful method to left-truncated…

Methodology · Statistics 2025-09-09 Kendrick Li , Mithun Kumar Acharjee

Area under the ROC curve, a.k.a. AUC, is a measure of choice for assessing the performance of a classifier for imbalanced data. AUC maximization refers to a learning paradigm that learns a predictive model by directly maximizing its AUC…

Machine Learning · Computer Science 2022-08-04 Tianbao Yang , Yiming Ying

Methods for the evaluation of the predictive accuracy of biomarkers with respect to survival outcomes subject to right censoring have been discussed extensively in the literature. In cancer and other diseases, survival outcomes are commonly…

Methodology · Statistics 2018-06-06 Yuan Wu , Xiaofei Wang , Jiaxing Lin , Beilin Jia , Kouros Owzar

The accuracy of a diagnostic test is typically characterised using the receiver operating characteristic (ROC) curve. Summarising indexes such as the area under the ROC curve (AUC) are used to compare different tests as well as to measure…

Methodology · Statistics 2010-12-30 Fang Yao , Radu V. Craiu , Benjamin Reiser

The Area Under the the Receiver Operating Characteristics (ROC) Curve, referred to as AUC, is a well-known performance measure in the supervised learning domain. Due to its compelling features, it has been employed in a number of studies to…

Machine Learning · Computer Science 2023-04-05 Pablo Andretta Jaskowiak , Ivan Gesteira Costa , Ricardo José Gabrielli Barreto Campello

The Area Under Curve measure (AUC) seems apt to evaluate and compare diverse models, possibly without calibration. An important example of AUC application is the evaluation and benchmarking of models that predict faithfulness of generated…

Computation and Language · Computer Science 2024-05-28 Juri Opitz

A popular technique for selecting and tuning machine learning estimators is cross-validation. Cross-validation evaluates overall model fit, usually in terms of predictive accuracy. In causal inference, the optimal choice of estimator…

Methodology · Statistics 2021-07-07 Dominik Rothenhäusler

We study the problem of selecting covariates for unbiased estimation of the total causal effect.Existing approaches typically rely on global causal structure learning over all variables, or on strong assumptions such as causal sufficiency -…

Machine Learning · Statistics 2026-05-22 Zeyu Liu , Zheng Li , Feng Xie , Yan Zeng , Hao Zhang , Kun Zhang

Accurate diagnosis of disease is of fundamental importance in clinical practice and medical research. Before a medical diagnostic test is routinely used in practice, its ability to distinguish between diseased and nondiseased states must be…

Methodology · Statistics 2018-06-05 Vanda Inacio de Carvalho , Maria Xose Rodriguez-Alvarez
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