Related papers: Ultrasensitive biosensor based on Nd:YAG waveguide…
Real-time monitoring of dynamic biological processes in the body is critical to understanding disease progression and treatment response. This data, for instance, can help address the lower than 50% response rates to cancer immunotherapy.…
Biomedical applications requiring tissue diagnosis, activation, and treatment could be substantially leveraged by optical methods, owing to their unique feature set. However, their widespread application is severely limited by the strong…
Devices based on photonic integrated circuits play a crucial role in the development of low-cost, high-performance, industry-scale manufacturable sensors. We report the design, fabrication, and application of a silicon nitride…
We experimentally demonstrate that pumping a graded-index multimode fiber with sub-ns pulses from a microchip Nd:YAG laser leads to spectrally flat supercontinuum generation with a uniform bell-shaped spatial beam profile extending from the…
Recently, nanomaterials are arousing increasing interest and a wide variety of opto-electronic devices have been developed, such as light-emitting diodes, solar cells, and photodetectors. However, the study of the light emission properties…
In the field of biomedicine magnetic beads are used for drug delivery and to treat hyperthermia. Here we propose to use self-organized bead structures to isolate circulating tumor cells using lab-on-chip technologies. Typically blood flows…
We propose an optical tactile sensor using self-healing materials. The proposed tactile sensor consists of a structure that includes a diode, a phototransistor, and an optical waveguide made from self-healing materials. This design offers…
The negatively-charged NV$^-$-center in diamond has shown great success in nanoscale, high-sensitivity magnetometry. Efficient fluorescence detection is crucial for improving the sensitivity. Furthermore, integrated devices enable…
Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting…
The paper explores the use of nanoparticles of gamma Fe2O3 for hyperthermia treatment of living organisms by absorption of 1064 nm radiations from Nd:YAG laser. Escherichia coli cells have been used as the model system for demonstrating the…
We have demonstrated the fabrication and characterization of 2D liquid-based multimode optical waveguide structures over a Polydimethylsiloxane (PDMS) material-based chip. Fabrication of two separate microstructures, one with a width of 14…
Annually, more than 16 billion medical needles are consumed worldwide. However, the functions of the medical needle are still limited to cutting and delivering or drawing material through the needle to a target site. Ultrasound combined…
Remarkable improvement in the removal efficiency of the ultraviolet laser (fourth harmonic wave of Nd:YAG laser) ablation was observed by irradiating a weak infrared laser (fundamental wave of Nd:YAG laser) simultaneously and additionally…
Metasurfaces are nano-structured devices composed of arrays of subwavelength scatterers (or meta-atoms) that manipulate the wavefront, polarization, or intensity of light. Like other diffractive optical devices, metasurfaces suffer from…
Intracellular lasers are emerging as powerful biosensors for multiplexed tracking and precision sensing of cells and their microenvironment. This sensing capacity is enabled by quantifying their narrow-linewidth emission spectra, which is…
An all-diamond photonic circuit was implemented by integrating a diamond microsphere with a femtosecond-laser-written bulk diamond waveguide. The near surface waveguide was fabricated by exploiting the Type II fabrication method to achieve…
We demonstrate a new highly tunable technique for generating meter-scale low density plasma waveguides. Such guides can enable electron acceleration to tens of GeV in a single stage. Plasma waveguides are imprinted in hydrogen gas by…
The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the development of a new generation of biosensors is diamond, due to its…
Angiogenesis, the formation of new vessels, is one of the key mechanisms in tumor development and an appealing target for therapy. Non-invasive, high-resolution, high sensitivity, quantitative 3D imaging techniques are required to correctly…
Sensors that are able to detect and track single unlabelled biomolecules are an important tool both to understand biomolecular dynamics and interactions at nanoscale, and for medical diagnostics operating at their ultimate detection limits.…