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Spike-timing dependent plasticity (STDP) is an organizing principle of biological neural networks. While synchronous firing of neurons is considered to be an important functional block in the brain, how STDP shapes neural networks possibly…

Neurons and Cognition · Quantitative Biology 2009-05-20 Yuko K. Takahashi , Hiroshi Kori , Naoki Masuda

Short-term presynaptic plasticity designates variations of the amplitude of synaptic information transfer whereby the amount of neurotransmitter released upon presynaptic stimulation changes over seconds as a function of the neuronal firing…

Neurons and Cognition · Quantitative Biology 2011-12-06 Maurizio De Pittà , Vladislav Volman , Hugues Berry , Eshel Ben-Jacob

The spontaneous emergence of contraction-inducing electrical activity in the uterus at the beginning of labor remains poorly understood, partly due to the seemingly contradictory observation that isolated uterine cells are not spontaneously…

Tissues and Organs · Quantitative Biology 2016-03-24 Jinshan Xu , Shakti N. Menon , Rajeev Singh , Nicolas B. Garnier , Sitabhra Sinha , Alain Pumir

At the macroscale, the brain operates as a network of interconnected neuronal populations, which display rhythmic dynamics that support interareal communication. Understanding how stimulation of a particular brain area impacts such…

Neurons and Cognition · Quantitative Biology 2020-11-12 Lia Papadopoulos , Christopher W. Lynn , Demian Battaglia , Danielle S. Bassett

Macroscopic properties and shapes of biological tissues depend on the remodelling of cell-cell junctions at the microscopic scale. We propose a theoretical framework that couples a vertex model of solid confluent tissues with the dynamics…

Soft Condensed Matter · Physics 2020-12-02 Clement Zankoc , Matej Krajnc

Latency reduction of postsynaptic spikes is a well-known effect of Synaptic Time-Dependent Plasticity. We expand this notion for long postsynaptic spike trains, showing that, for a fixed input spike train, STDP reduces the number of…

Neurons and Cognition · Quantitative Biology 2019-07-26 Pau Vilimelis Aceituno , Masud Ehsani , Jürgen Jost

Sleep is thought to support memory consolidation and the recovery of optimal energetic regime by reorganizing synaptic connectivity, yet how plasticity across hierarchical brain circuits contributes to abstraction and energy efficiency…

We here study a network of synaptic relations mingling excitatory and inhibitory neuron nodes that displays oscillations quite similar to electroencephalogram (EEG) brain waves, and identify abrupt variations brought about by swift synaptic…

Neurons and Cognition · Quantitative Biology 2021-02-17 Jorge Pretel , Joaquin J. Torres , J. Marro

Increasing experimental evidence suggests that axonal action potential conduction velocity is a highly adaptive parameter in the adult central nervous system. Yet, the effects of this newfound plasticity on global brain dynamics is poorly…

Neurons and Cognition · Quantitative Biology 2019-03-26 Vladimir A. Ivanov , Ioannis E. Polykretis , Konstantinos P. Michmizos

The theta rhythm is important for many cognitive functions including spatial processing, memory encoding, and memory recall. The information processing underlying these functions is thought to rely on consistent, phase-specific spiking…

Neurons and Cognition · Quantitative Biology 2025-10-16 Oleg Makarenkov , Marianne Bezaire , Michael Hasselmo

Understanding cognitive processes in the brain demands sophisticated models capable of replicating neural dynamics at large scales. We present a physiologically inspired speech recognition architecture, compatible and scalable with deep…

Computation and Language · Computer Science 2024-09-26 Alexandre Bittar , Philip N. Garner

The feedback between mechanical and chemical signals plays a key role in controlling many biological processes and collective cell behavior. Here we focus on the emergence of spatiotemporal density waves in a one-dimensional "cell train."…

Biological Physics · Physics 2025-02-12 Toshi Parmar , Liam P. Dow , Beth L. Pruitt , M. Cristina Marchetti

The retina is the entrance of the visual system. Although based on common biophysical principles the dynamics of retinal neurons is quite different from their cortical counterparts, raising interesting problems for modellers. In this paper…

Dynamical Systems · Mathematics 2022-01-20 Bruno Cessac

Cortical networks can maintain memories for decades despite the short lifetime of synaptic strength. Can a neural network store long-lasting memories in unstable synapses? Here, we study the effects of random noise on the stability of…

Neurons and Cognition · Quantitative Biology 2012-06-01 Yi Wei , Alexei A. Koulakov

A common model to study pattern formation in large groups of neurons is the neural field. We investigate a neural field with excitatory and inhibitory neurons, like Wilson and Cowan (1972), with transmission delays and gap junctions. We…

Dynamical Systems · Mathematics 2023-02-20 Len Spek , Stephan A. van Gils , Yuri A. Kuznetsov , Mónika Polner

Networks of fast-spiking interneurons are crucial for the generation of neural oscillations in the brain. Here we study the synchronous behavior of interneuronal networks that are coupled by delayed inhibitory and fast electrical synapses.…

Neurons and Cognition · Quantitative Biology 2012-06-22 Daqing Guo , Qingyun Wang , Matjaz Perc

We consider spin effects related to the random spin-orbit interaction in graphene. Such a random interaction can result from the presence of ripples and/or other inhomogeneities at the graphene surface. We show that the random spin-orbit…

Mesoscale and Nanoscale Physics · Physics 2015-05-20 V. K. Dugaev , E. Ya. Sherman , J. Barnas

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

Neurons and Cognition · Quantitative Biology 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

We analyze continuous Hopfield associative memories augmented by additional, rapid short-term associative synaptic plasticity. Through the cavity method, we determine the boundary between the retrieval and forgetting, or spin-glass phase,…

Neurons and Cognition · Quantitative Biology 2026-02-10 Martina Del Gaudio , Federico Ghimenti , Surya Ganguli

Brain oscillations exhibit long-range temporal correlations (LRTCs), which reflect the regularity of their fluctuations: low values representing more random (decorrelated) while high values more persistent (correlated) dynamics. LRTCs…

Neurons and Cognition · Quantitative Biology 2018-02-05 Tomas Ros , Paul Frewen , Jean Theberge , Rosemarie Kluetsch , Andreas Mueller , Gian Candrian , Rakesh Jetly , Patrik Vuilleumier , Ruth Lanius