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Growing experimental evidence indicates that topological defects could serve as organizing centers in the morphogenesis of tissues. Here, we provide a quantitative explanation for this phenomenon, rooted in the buckling theory of deformable…

Soft Condensed Matter · Physics 2022-04-21 Ludwig A. Hoffmann , Livio Nicola Carenza , Julia Eckert , Luca Giomi

Active stresses in biological cells and tissues drive many developmental processes. However, increasing experimental evidence suggests that additional mechanical interactions with surrounding material can play a crucial role in guiding…

Soft Condensed Matter · Physics 2026-03-10 Douglas MacMyn Brown , Alexander Mietke

We present an analytical and numerical investigation of the activity-induced hydrodynamic instabilities in model brain organoids. While several mechanisms have been introduced to explain the experimental observation of surface instabilities…

Soft Condensed Matter · Physics 2021-11-08 Kristian Thijssen , Guido L. A. Kusters , Amin Doostmohammadi

One of the defining features of active nematics is that above a critical activity the quiescent state becomes unstable to a distorted, flowing one. We show that spatial variations in activity can fundamentally change the nature of this…

Soft Condensed Matter · Physics 2025-12-15 Alexander J. H. Houston , Michael Grinfeld , Geoff McKay , Nigel J. Mottram

We study analytically and numerically a generic continuum model of an isotropic active solid with internal stresses generated by non-equilibrium `active' mechano-chemical reactions. Our analysis shows that the gel can be tuned through three…

Soft Condensed Matter · Physics 2015-05-30 Shiladitya Banerjee , Tanniemola B. Liverpool , M. Cristina Marchetti

Depending on the involved physiobiological parameters, stable or unstable behavior in active fluids is observed. In this paper a rigorous analytical justification of (in-)stability within the corresponding regimes is given. In particular,…

Analysis of PDEs · Mathematics 2023-08-03 Christiane Bui , Christian Gesse , Jürgen Saal

The complex physics of self-assembly in colloidal crystals on deformable interfaces and surfaces poses interesting possibilities for the designability and synthesis of next-generation metamaterials. The goal of this article is to…

Soft Condensed Matter · Physics 2025-06-23 Sanjay Dharmavaram , Basant Lal Sharma

The lack of detailed balance in active colloidal suspensions allows dissipation to determine stationary states. Here we show that slow viscous flow produced by polar or apolar active colloids near plane walls mediates attractive…

Soft Condensed Matter · Physics 2016-11-24 Rajesh Singh , R. Adhikari

Wet active matter in the presence of an imposed temperature gradient, or chemical potential gradient, is considered. It is shown that there is a new type of convective instability that is caused by a (negative) activity parameter.…

Soft Condensed Matter · Physics 2019-02-15 T. R. Kirkpatrick , J. K. Bhattacherjee

Meso-scale turbulence was originally observed experimentally in various suspensions of swimming bacteria, as well as in the collective motion of active colloids. The corresponding large-scale dynamical patterns were reproduced in a simple…

Soft Condensed Matter · Physics 2021-03-30 Vasco M. Worlitzer , Gil Ariel , Avraham Be'er , Holger Stark , Markus Bär , Sebastian Heidenreich

Starting from a three-dimensional description of an active nematic layer, we employ an asymptotic theory to derive a series of low-dimensional continuum models that capture the coupled dynamics of flat and curved films, including variations…

Soft Condensed Matter · Physics 2025-06-23 Mehrana R. Nejad , L. Mahadevan

We consider a mixture of passive (i.e., Brownian) and active (e.g., bacterial or colloidal swimmers) particles, and analyze the stability conditions of either uniformly mixed or phase segregated steady states consisting of phases enriched…

Statistical Mechanics · Physics 2015-09-21 Alexander Y. Grosberg , Jean-François Joanny

Polydisperse mixtures are those in which components with a whole range of sizes are present. It is shown that the fluid phase of polydisperse hard spheres is thermodynamically unstable unless the density of large spheres decreases at least…

Soft Condensed Matter · Physics 2009-10-31 Richard P. Sear

A collection of microswimmers immersed in an incompressible fluid is characterised by strong interactions due to the long-range nature of the hydrodynamic fields generated by individual organisms. As a result, suspensions of rear-actuated…

Soft Condensed Matter · Physics 2023-12-19 Viktor Škultéty , Dóra Bárdfalvy , Joakim Stenhammar , Cesare Nardini , Alexander Morozov

Collective cell migration plays a crucial role in many developmental processes that underlie morphogenesis, wound healing, or cancer progression. In such coordinated behaviours, cells are organised in coherent structures and actively…

Soft Condensed Matter · Physics 2021-06-16 Carolina Trenado , Luis L. Bonilla , Alejandro Martínez-Calvo

The evolution of an instability at the interface of active and passive media is considered. An asymptotic form of a collision integral is found and the limitations of hydrodynamic approach are determined. A growth increment of small…

Plasma Physics · Physics 2013-12-23 Sergey Kuratov , Andrey Mikulin

We develop a general classification of the nature of the instabilities yielding spatial organization in open nonideal reaction-diffusion systems, based on linear stability analysis. This encompasses dynamics where chemical species diffuse,…

Statistical Mechanics · Physics 2023-10-05 Timur Aslyamov , Francesco Avanzini , Étienne Fodor , Massimiliano Esposito

Hydrodynamic instabilities in miscible fluids are ubiquitous, from natural phenomena up to geological scales, to industrial and technological applications, where they represent the only way to control and promote mixing at low Reynolds…

Soft Condensed Matter · Physics 2017-12-21 Domenico Truzzolillo , Luca Cipelletti

Phase separation is the thermodynamic process that explains how droplets form in multicomponent fluids. These droplets can provide controlled compartments to localize chemical reactions, and reactions can also affect the droplets' dynamics.…

Soft Condensed Matter · Physics 2022-09-02 David Zwicker

We numerically solve the active nematohydrodynamic equations of motion, coupled to a Turing reaction-diffusion model, to study the effect of active nematic flow on the stripe patterns resulting from a Turing instability. If the activity is…

Soft Condensed Matter · Physics 2021-11-04 Saraswat Bhattacharyya , Julia M. Yeomans