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Coronary angiography is considered to be a safe tool for the evaluation of coronary artery disease and perform in approximately 12 million patients each year worldwide. [1] In most cases, angiograms are manually analyzed by a cardiologist.…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Stanislav Filippov , Arsenii Moiseev , Andronenko Andrey

Non-contrast computed tomography calcium scoring (CTCS) is a cost-effective imaging modality widely used to detect coronary artery calcifications. This study aimed to develop an advanced machine learning framework that utilizes quantitative…

Coronary calcium causes beam hardening and blooming artifacts on cardiac computed tomography angiography (CTA) images, which lead to overestimation of lumen stenosis and reduction of diagnostic specificity. To properly remove coronary…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Siming Yan , Feng Shi , Yuhua Chen , Damini Dey , Sang-Eun Lee , Hyuk-Jae Chang , Debiao Li , Yibin Xie

Background. Coronary artery calcium (CAC) is a powerful predictor of major adverse cardiovascular events (MACE). Traditional Agatston score simply sums the calcium, albeit in a non-linear way, leaving room for improved calcification…

Quantitative Methods · Quantitative Biology 2023-08-24 Ammar Hoori , Sadeer Al-Kindi , Tao Hu , Yingnan Song , Hao Wu , Juhwan Lee , Nour Tashtish , Pingfu Fu , Robert Gilkeson , Sanjay Rajagopalan , David L. Wilson

Calcium imaging is a technique for observing neuron activity as a series of images showing indicator fluorescence over time. Manually segmenting neurons is time-consuming, leading to research on automated calcium imaging segmentation…

Computer Vision and Pattern Recognition · Computer Science 2017-07-21 Aleksander Klibisz , Derek Rose , Matthew Eicholtz , Jay Blundon , Stanislav Zakharenko

Coronary artery disease leading up to stenosis, the partial or total blocking of coronary arteries, is a severe condition that affects millions of patients each year. Automated identification and classification of stenosis severity from…

Image and Video Processing · Electrical Eng. & Systems 2021-03-05 Dinis L. Rodrigues , Miguel Nobre Menezes , Fausto J. Pinto , Arlindo L. Oliveira

Early detection of coronary artery disease (CAD) is critical for reducing mortality and improving patient treatment planning. While angiographic image analysis from X-rays is a common and cost-effective method for identifying cardiac…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Alvee Hassan , Rusab Sarmun , Muhammad E. H. Chowdhury , M Murugappan , Abdulrahman Alqahtani , Balamurugan Balusamy , Sohaib Bassam Zoghoul

The determination of a coronary stenosis and its severity in current clinical workflow is typically accomplished manually via physician visual assessment (PVA) during invasive coronary angiography. While PVA has shown large inter-rater…

Computer Vision and Pattern Recognition · Computer Science 2018-07-30 Benjamin Au , Uri Shaham , Sanket Dhruva , Georgios Bouras , Ecaterina Cristea , Alexandra Lansky MD , Andreas Coppi , Fred Warner , Shu-Xia Li , Harlan Krumholz

Incidental detection and quantification of coronary calcium in CT scans could lead to the early introduction of lifesaving clinical interventions. However, over-reporting could negatively affect patient wellbeing and unnecessarily burden…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Olivier Jaubert , Salman Mohammadi , Keith A. Goatman , Shadia S. Mikhael , Conor Bradley , Rebecca Hughes , Richard Good , John H. Hipwell , Sonia Dahdouh

Coronary artery calcium (CAC) scoring is a key predictor of cardiovascular risk, but it relies on ECG-gated CT scans, restricting its use to specialized cardiac imaging settings. We introduce an automated framework for CAC detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-02-26 Mahmut S. Gokmen , Moneera N. Haque , Steve W. Leung , Caroline N. Leach , Seth Parker , Stephen B. Hobbs , Vincent L. Sorrell , W. Brent Seales , V. K. Cody Bumgardner

Atherosclerosis, a chronic inflammatory disease affecting the large arteries, presents a global health risk. Accurate analysis of diagnostic images, like computed tomographic angiograms (CTAs), is essential for staging and monitoring the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Alireza Bagheri Rajeoni , Breanna Pederson , Daniel G. Clair , Susan M. Lessner , Homayoun Valafar

With coronary artery disease (CAD) persisting to be one of the leading causes of death worldwide, interest in supporting physicians with algorithms to speed up and improve diagnosis is high. In clinical practice, the severeness of CAD is…

Accurate extraction of coronary arteries from invasive coronary angiography (ICA) is important in clinical decision-making for the diagnosis and risk stratification of coronary artery disease (CAD). In this study, we develop a method using…

Image and Video Processing · Electrical Eng. & Systems 2023-12-22 Yinghui Meng , Zhenglong Du , Chen Zhao , Minghao Dong , Drew Pienta , Zhihui Xu , Weihua Zhou

This study proposes an efficient neural network with convolutional layers to classify significantly class-imbalanced clinical data. The data are curated from the National Health and Nutritional Examination Survey (NHANES) with the goal of…

Quantitative Methods · Quantitative Biology 2020-04-24 Aniruddha Dutta , Tamal Batabyal , Meheli Basu , Scott T. Acton

The classification of the electrocardiogram (ECG) signal has a vital impact on identifying heart-related diseases. This can ensure the premature finding of heart disease and the proper selection of the patient's customized treatment.…

Non-contrast computed tomography calcium scoring (CTCS) is widely recognized as an effective tool for cardiovascular risk stratification. This study aimed to develop a novel machine learning framework for predicting myocardial ischemia from…

Machine Learning · Computer Science 2026-05-22 Juhwan Lee , Sadeer Al-Kindi , Ammar Hoori , Tao Hu , Hao Wu , Justin N. Kim , Robert Gilkeson , Sanjay Rajagopalan , David L. Wilson

Coronary Artery Disease (CAD) is one of the leading causes of death worldwide, and so it is very important to correctly diagnose patients with the disease. For medical diagnosis, machine learning is a useful tool, however features and…

Machine Learning · Computer Science 2018-12-10 Ali Bou Nassif , Omar Mahdi , Qassim Nasir , Manar Abu Talib , Mohammad Azzeh

The standard non-invasive imaging technique used to assess the severity and extent of Coronary Artery Disease (CAD) is Coronary Computed Tomography Angiography (CCTA). However, manual grading of each patient's CCTA according to the…

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

Myocardial characterization is essential for patients with myocardial infarction and other myocardial diseases, and the assessment is often performed using cardiac magnetic resonance (CMR) sequences. In this study, we propose a fully…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Xiaoran Zhang , Michelle Noga , Kumaradevan Punithakumar