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Although tissues are usually studied in isolation, this situation rarely occurs in biology, as cells, tissues, and organs, coexist and interact across scales to determine both shape and function. Here, we take a quantitative approach…

Tissues and Organs · Quantitative Biology 2023-02-07 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

Regularity properties of solutions for a class of quasi-stationary models in one spatial dimension for stress-modulated growth in the presence of a nutrient field are proven. At a given point in time the configuration of a body after pure…

Analysis of PDEs · Mathematics 2025-07-31 Julian Blawid , Georg Dolzmann

We study the dynamics of an exactly solvable lattice model for inhomogeneous interface growth. The interface grows deterministically with constant velocity except along a defect line where the growth process is random. We obtain exact…

Condensed Matter · Physics 2009-10-28 Gunter M. Schütz

We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…

Analysis of PDEs · Mathematics 2015-06-22 Donatella Donatelli , Konstantina Trivisa

An important question in biology is how the relative size of different organs is kept nearly constant during growth of an animal. This property, called proportionate growth, has received increased attention in recent years. We discuss our…

Statistical Mechanics · Physics 2014-11-18 Tridib Sadhu , Deepak Dhar

Tissue growth kinetics and interface dynamics depend on the properties of the tissue environment and cell-cell interactions. In cellular environments, substrate heterogeneity and geometry arise from a variety factors, such as the structure…

Soft Condensed Matter · Physics 2023-03-21 Mahmood Mazarei , Jan Astrom , Jan Westerlund , Mikko Karttunen

Why are large, complex ecosystems stable? Both theory and simulations of current models predict the onset of instability with growing size and complexity, so for decades it has been conjectured that ecosystems must have some unidentified…

Populations and Evolution · Quantitative Biology 2016-08-11 Samuel Johnson , Virginia Domínguez-García , Luca Donetti , Miguel A. Muñoz

In this paper we present a study of local dynamics of the growth of cancer tumor and healthy cells considering the presence of nutrients in the system. We also analyze the evolution of system if we take indirectly into account the level of…

Biological Physics · Physics 2019-01-29 Cristian C. Pérez Águila , Maura Cárdenas G. , J. Fernando Rojas

When a soft glassy colloidal suspension is displaced by a Newtonian fluid in a radial Hele-Shaw geometry, the pattern morphology that develops at the interface is determined by the complex rheology of the former. We had reported in an…

Soft Condensed Matter · Physics 2022-10-18 Palak , Vaibhav Raj Singh Parmar , Ranjini Bandyopadhyay

We consider a diffuse interface model for tumor growth recently proposed in [Y. Chen, S.M. Wise, V.B. Shenoy, J.S. Lowengrub, A stable scheme for a nonlinear, multiphase tumor growth model with an elastic membrane, Int. J. Numer. Methods…

Analysis of PDEs · Mathematics 2015-07-29 Mimi Dai , Eduard Feireisl , Elisabetta Rocca , Giulio Schimperna , Maria Schonbek

The roughening behavior of a one-dimensional interface fluctuating under quenched disorder growth is examined while keeping an anchored boundary. The latter introduces detailed balance conditions which allows for a thorough analysis of…

Statistical Mechanics · Physics 2007-05-23 M. D. Grynberg

A model for morphoelastic growth, that is, growth influenced by elastic stress, driven by the absorption of nutrients is considered. The model features a multiplicative decomposition of the deformation gradient into an elastic contribution…

Analysis of PDEs · Mathematics 2026-05-05 Helmut Abels , Julian Blawid , Georg Dolzmann

Under natural conditions, excitation of biological molecules, which display non-unitary open system dynamics, occurs via incoherent processes such as temperature changes or irradiation by sunlight/moonlight. The dynamics of such processes…

Quantum Physics · Physics 2013-02-11 Leonardo A. Pachon , Paul Brumer

We investigate the growth of a film of some element B on a substrate made of another substrance A in a model of molecular beam epitaxy. A vertical exchange mechanism allows the A-atoms to stay on the growing surface with a certain…

Statistical Mechanics · Physics 2009-11-10 Boris Bierwald , Michael von den Driesch , Zeno Farkas , Sang Bub Lee , Dietrich E. Wolf

A growing interface subject to noise is described by the Kardar-Parisi-Zhang equation or, equivalently, the noisy Burgers equation. In one dimension this equation is analyzed by means of a weak noise canonical phase space approach applied…

Statistical Mechanics · Physics 2014-10-07 Hans C Fogedby

The buckling of a soft elastic sample under growth or swelling has highlighted a new interest in materials science, morphogenesis, and biology or physiology. Indeed, the change of mass or volume is a common fact of any living species, and…

Soft Condensed Matter · Physics 2023-09-21 Martine Ben Amar

A dynamical systems scenario for developmental cell biology is proposed, based on numerical studies of a system with interacting units with internal dynamics and reproduction. Diversification, formation of discrete and recursive types, and…

chao-dyn · Physics 2009-10-31 Kunihiko Kaneko , Chikara Furusawa

Growth occurs in a wide range of systems ranging from biological tissue to additive manufacturing. This work considers surface growth, in which mass is added to the boundary of a continuum body from the ambient medium or from within the…

Analysis of PDEs · Mathematics 2021-05-27 Kiana Naghibzadeh , Noel Walkington , Kaushik Dayal

It is shown that, by imposing reparametrization invariance, one may derive a variety of stochastic equations describing the dynamics of surface growth and identify the physical processes responsible for the various terms. This approach…

Condensed Matter · Physics 2009-10-28 M. Marsili , A. Maritan , F. Toigo , J. R. Banavar

We study a model introduced by Perthame and Vauchelet that describes the growth of a tumor governed by Brinkman's Law, which takes into account friction between the tumor cells. We adopt the viscosity solution approach to establish an…

Analysis of PDEs · Mathematics 2017-04-24 Inwon Kim , Olga Turanova