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We study super-resolution multi-reference alignment, the problem of estimating a signal from many circularly shifted, down-sampled, and noisy observations. We focus on the low SNR regime, and show that a signal in $\mathbb{R}^M$ is uniquely…

Information Theory · Computer Science 2020-11-10 Tamir Bendory , Ariel Jaffe , William Leeb , Nir Sharon , Amit Singer

Multi-reference alignment entails estimating a signal in $\mathbb{R}^L$ from its circularly-shifted and noisy copies. This problem has been studied thoroughly in recent years, focusing on the finite-dimensional setting (fixed $L$).…

Information Theory · Computer Science 2021-10-01 Elad Romanov , Tamir Bendory , Or Ordentlich

We propose a Bayesian approach to the problem of multi-reference alignment -- the recovery of signals from noisy, randomly shifted observations. While existing frequentist methods accurately recover the signal at arbitrarily low…

Signal Processing · Electrical Eng. & Systems 2025-10-15 Axel Janson , Joakim Andén

Multireference alignment (MRA) problem is to estimate an underlying signal from a large number of noisy circularly-shifted observations. The existing methods are always proposed under the hypothesis of a single Gaussian noise. However, the…

Optimization and Control · Mathematics 2021-07-23 Cuicui Zhao , Jun Liu , Xinqi Gong

The Boolean multireference alignment problem consists in recovering a Boolean signal from multiple shifted and noisy observations. In this paper we obtain an expression for the error exponent of the maximum A posteriori decoder. This…

Information Theory · Computer Science 2017-02-06 Emmanuel Abbe , Joao Pereira , Amit Singer

We consider the problem of estimating a signal from noisy circularly-translated versions of itself, called multireference alignment (MRA). One natural approach to MRA could be to estimate the shifts of the observations first, and infer the…

Information Theory · Computer Science 2018-02-14 Tamir Bendory , Nicolas Boumal , Chao Ma , Zhizhen Zhao , Amit Singer

The Multi-Reference Alignment (MRA) problem aims at the recovery of an unknown signal from repeated observations under the latent action of a group of cyclic isometries, in the presence of additive noise of high intensity $\sigma$. It is a…

Statistics Theory · Mathematics 2023-12-14 Subhro Ghosh , Soumendu Sundar Mukherjee , Jing Bin Pan

We study the dihedral multi-reference alignment problem of estimating the orbit of a signal from multiple noisy observations of the signal, acted on by random elements of the dihedral group. We show that if the group elements are drawn from…

Information Theory · Computer Science 2022-01-05 Tamir Bendory , Dan Edidin , William Leeb , Nir Sharon

Motivated by cutting-edge applications like cryo-electron microscopy (cryo-EM), the Multi-Reference Alignment (MRA) model entails the learning of an unknown signal from repeated measurements of its images under the latent action of a group…

Statistics Theory · Mathematics 2022-03-11 Subhro Ghosh , Philippe Rigollet

Motivated by single-particle cryo-electron microscopy, multi-reference alignment (MRA) models the task of recovering an unknown signal from multiple noisy observations corrupted by random rotations. The standard approach,…

Signal Processing · Electrical Eng. & Systems 2026-01-09 Shay Kreymer , Amnon Balanov , Tamir Bendory

Motivated by the problem of determining the atomic structure of macromolecules using single-particle cryo-electron microscopy (cryo-EM), we study the sample and computational complexities of the sparse multi-reference alignment (MRA) model:…

Information Theory · Computer Science 2021-09-27 Tamir Bendory , Oscar Mickelin , Amit Singer

Multireference alignment (MRA) refers to the problem of recovering a signal from noisy samples subject to random circular shifts. Expectation--maximization (EM) and variational approaches use statistical modeling to achieve high accuracy at…

Information Theory · Computer Science 2025-10-30 Vahid Shahverdi , Emanuel Ström , Joakim Andén

The multireference alignment problem consists of estimating a signal from multiple noisy shifted observations. Inspired by existing Unique-Games approximation algorithms, we provide a semidefinite program (SDP) based relaxation which…

Data Structures and Algorithms · Computer Science 2013-08-27 Afonso S. Bandeira , Moses Charikar , Amit Singer , Andy Zhu

Sampling from multimodal distributions is a challenging task in scientific computing. When a distribution has an exact symmetry between the modes, direct jumps among them can accelerate the samplings significantly. However, the…

Numerical Analysis · Mathematics 2024-01-05 Lexing Ying

Motivated by the structure reconstruction problem in single-particle cryo-electron microscopy, we consider the multi-target detection model, where multiple copies of a target signal occur at unknown locations in a long measurement, further…

Information Theory · Computer Science 2020-04-22 Ti-Yen Lan , Tamir Bendory , Nicolas Boumal , Amit Singer

The multi-reference alignment (MRA) problem entails estimating an image from multiple noisy and rotated copies of itself. If the noise level is low, one can reconstruct the image by estimating the missing rotations, aligning the images, and…

Signal Processing · Electrical Eng. & Systems 2022-06-17 Noam Janco , Tamir Bendory

This paper proposes a novel Bayesian reciprocity calibration method that consistently ensures uplink and downlink channel reciprocity in repeater-assisted multiple-input multiple-output (MIMO) systems. The proposed algorithm is formulated…

Signal Processing · Electrical Eng. & Systems 2026-02-06 Shoma Hara , Takumi Takahashi , Hiroki Iimori , Hideki Ochiai , Erik G. Larsson

We study the continuous multi-reference alignment model of estimating a periodic function on the circle from noisy and circularly-rotated observations. Motivated by analogous high-dimensional problems that arise in cryo-electron microscopy,…

Statistics Theory · Mathematics 2023-08-29 Zehao Dou , Zhou Fan , Harrison Zhou

Multi-reference alignment (MRA) is the problem of recovering a signal from its multiple noisy copies, each acted upon by a random group element. MRA is mainly motivated by single-particle cryo-electron microscopy (cryo-EM) that has recently…

Information Theory · Computer Science 2023-08-15 Tamir Bendory , Dan Edidin

The growing role of data-driven approaches to scientific discovery has unveiled a large class of models that involve latent transformations with a rigid algebraic constraint. Three-dimensional molecule reconstruction in Cryo-Electron…

Information Theory · Computer Science 2019-06-04 Amelia Perry , Jonathan Weed , Afonso S. Bandeira , Philippe Rigollet , Amit Singer
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