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Problem definition: Personalized medicine (PM) seeks the best treatment for each patient among a set of available treatment methods. Since a specific treatment does not work well on all patients, traditionally, the best treatment was…

Optimization and Control · Mathematics 2023-08-03 Jianzhong Du , Siyang Gao , Chun-Hung Chen

We consider a simulation-based Ranking and Selection (R&S) problem with input uncertainty, where unknown input distributions can be estimated using input data arriving in batches of varying sizes over time. Each time a batch arrives,…

Optimization and Control · Mathematics 2022-09-05 Di Wu , Yuhao Wang , Enlu Zhou

Ranking and selection (R&S) is a popular model for studying discrete-event dynamic systems. It aims to select the best design (the design with the largest mean performance) from a finite set, where the mean of each design is unknown and has…

Machine Learning · Statistics 2022-11-29 Yanwen Li , Siyang Gao , Zhongshun Shi

We want to select the best systems out of a given set of systems (or rank them) with respect to their expected performance. The systems allow random observations only and we assume that the joint observation of the systems has a…

Methodology · Statistics 2017-01-23 Björn Görder , Michael Kolonko

Ranking and selection (R&S) aims to select the best alternative with the largest mean performance from a finite set of alternatives. Recently, considerable attention has turned towards the large-scale R&S problem which involves a large…

Methodology · Statistics 2025-09-09 Zaile Li , Weiwei Fan , L. Jeff Hong

The goal of ranking and selection (R&S) procedures is to identify the best stochastic system from among a finite set of competing alternatives. Such procedures require constructing estimates of each system's performance, which can be…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-06-17 Eric C. Ni , Dragos F. Ciocan , Shane G. Henderson , Susan R. Hunter

Robust ranking and selection (R&S) is an important and challenging variation of conventional R&S that seeks to select the best alternative among a finite set of alternatives. It captures the common input uncertainty in the simulation model…

Methodology · Statistics 2025-09-23 Yuchen Wan , Zaile Li , L. Jeff Hong

This research considers the ranking and selection with input uncertainty. The objective is to maximize the posterior probability of correctly selecting the best alternative under a fixed simulation budget, where each alternative is measured…

Optimization and Control · Mathematics 2023-05-15 Hui Xiao , Zhihong Wei

Adjusting for covariates in randomized controlled trials can enhance the credibility and efficiency of treatment effect estimation. However, handling numerous covariates and their complex (non-linear) transformations poses a challenge.…

Methodology · Statistics 2025-10-22 Yi Liu , Ke Zhu , Larry Han , Shu Yang

Recommendation systems (RSs) are increasingly used to guide job seekers on online platforms, yet the algorithms currently deployed are typically optimized for predictive objectives such as clicks, applications, or hires, rather than job…

We address the problem of policy selection in contextual stochastic optimization (CSO), where covariates are available as contextual information and decisions must satisfy hard feasibility constraints. In many CSO settings, multiple…

Machine Learning · Computer Science 2026-05-29 Caio de Prospero Iglesias , Kimberly Villalobos Carballo , Dimitris Bertsimas

We explore and illustrate the concept of ranked sparsity, a phenomenon that often occurs naturally in modeling applications when an expected disparity exists in the quality of information between different feature sets. Its presence can…

Methodology · Statistics 2022-01-28 Ryan A. Peterson , Joseph E. Cavanaugh

Specifying a proper input distribution is often a challenging task in simulation modeling. In practice, there may be multiple plausible distributions that can fit the input data reasonably well, especially when the data volume is not large.…

Methodology · Statistics 2019-03-15 Weiwei Fan , L. Jeff Hong , Xiaowei Zhang

Variable selection for optimal treatment regime in a clinical trial or an observational study is getting more attention. Most existing variable selection techniques focused on selecting variables that are important for prediction, therefore…

Methodology · Statistics 2014-05-22 Ailin Fan , Wenbin Lu , Rui Song

Decision-making problems often feature uncertainty stemming from heterogeneous and context-dependent human preferences. To address this, we propose a sequential learning-and-optimization pipeline to learn preference distributions and…

Machine Learning · Computer Science 2026-03-19 Benjamin Hudson , Laurent Charlin , Emma Frejinger

Top-N recommendation, which aims to learn user ranking-based preference, has long been a fundamental problem in a wide range of applications. Traditional models usually motivate themselves by designing complex or tailored architectures…

Information Retrieval · Computer Science 2021-09-14 Mengyue Yang , Quanyu Dai , Zhenhua Dong , Xu Chen , Xiuqiang He , Jun Wang

In many real world problems, we are faced with the problem of selecting the best among a finite number of alternatives, where the best alternative is determined based on context specific information. In this work, we study the contextual…

Optimization and Control · Mathematics 2022-01-20 Sait Cakmak , Siyang Gao , Enlu Zhou

We consider the problem of sequential evaluation, in which an evaluator observes candidates in a sequence and assigns scores to these candidates in an online, irrevocable fashion. Motivated by the psychology literature that has studied…

Machine Learning · Statistics 2023-11-20 Jingyan Wang , Ashwin Pananjady

Randomized experimentation (also known as A/B testing or bucket testing) is widely used in the internet industry to measure the metric impact obtained by different treatment variants. A/B tests identify the treatment variant showing the…

The task of a personalization system is to recommend items or a set of items according to the users' taste, and thus predicting their future needs. In this paper, we address such personalized recommendation problems for which one-bit…

Information Retrieval · Computer Science 2022-08-10 Aria Ameri , Arindam Bose , Mojtaba Soltanalian
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