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Transport of molecules across membrane channels is investigated theoretically using exactly solvable discrete stochastic site-binding models. It is shown that the interaction potential between molecules and the channel has a strong effect…

Soft Condensed Matter · Physics 2009-11-11 Anatoly B. Kolomeisky

Transport of molecules across membrane channels is investigated theoretically using exactly solvable one-dimensional discrete-state stochastic models. An interaction between molecules and membrane pores is modeled via a set of binding sites…

Soft Condensed Matter · Physics 2009-11-13 Anatoly B. Kolomeisky , Stanislav Kotsev

A novel mechanism for the transport of microscale particles in viscous fluids is demonstrated. The mechanism exploits the trapping of such particles by rotational streaming cells established in the vicinity of an oscillating cylinder,…

Fluid Dynamics · Physics 2016-01-13 Kwitae Chong , Scott D. Kelly , Stuart T. Smith , Jeff D. Eldredge

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

Soft Condensed Matter · Physics 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

We consider an anisotropically two-dimensional diffusion of a charged molecule (particle) through a large biological channel under an external voltage. The channel is modeled as a cylinder of three structure parameters: radius, length, and…

Soft Condensed Matter · Physics 2016-02-01 V. T. N. Huyen , Le Bin Ho , Vu Cong Lap , V. Lien Nguyen

Channel proteins, that selectively conduct molecules across cell membranes, often exhibit an asymmetric structure. By means of a stochastic model, we argue that channel asymmetry in the presence of non-equilibrium fluctuations, fueled by…

Biological Physics · Physics 2007-05-23 Ioan Kosztin , Klaus Schulten

The transport of particles through channels holds immense significance in physics, chemistry, and biological sciences. For instance, the motion of solutes through biological channels is facilitated by specialized proteins that create…

Statistical Mechanics · Physics 2024-07-22 Suvam Pal , Denis Boyer , Leonardo Dagdug , Arnab Pal

We investigate the transport dynamics of elongated particles in cellular vortical flows that undergo spatial oscillations over time. Experimental flow visualizations reveal mixed flow fields with chaotic and elliptic regions coexisting.…

Fluid Dynamics · Physics 2025-08-14 Shiyuan Hu , Xiuyuan Yang , Nan Luo , Jun Zhang , Xingkun Man

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

Collective transport through channels shows surprising properties under one-dimensional confinement: particles in a single file exhibit sub-diffusive behavior, while liquid confinement causes distance-independent correlations between the…

Soft Condensed Matter · Physics 2019-06-05 Karolis Misiunas , Ulrich F. Keyser

An analytical analysis is presented of the transport and capture of magnetic micro/nano-particles in a magnetophoretic microsystem that consists of an array of integrated soft-magnetic elements embedded beneath a microfluidic channel. The…

Biological Physics · Physics 2009-11-13 E. P. Furlani

We construct a new statistical physical model of polymer translocation through a pore in a membrane treated as the diffusion process across a free energy barrier. We determine the translocation time in terms of chain flexibility yielding an…

Soft Condensed Matter · Physics 2015-06-25 W. Sung , P. J. Park

A mechanism responsible for the directed transport and molecular separation in a symmetric channel is proposed. We found that under the action of spatial harmonic oscillations of the channel, the system exhibits a directed transport in…

Soft Condensed Matter · Physics 2007-05-23 D. Lichtenberg , A. E. Filippov , M. Urbakh

Particle transport through an open, discrete 1-D channel against a mechanical or chemical bias is analyzed within a master equation approach. The channel, externally driven by time dependent site energies, allows multiple occupation due to…

Statistical Mechanics · Physics 2015-05-18 Mario Einax , Gemma Solomon , Wolfgang Dieterich , Abraham Nitzan

The paper deals with a theoretical investigation of the peristaltic transport of a physiological fluid in a porous asymmetric channel under the action of a magnetic field. The stream function, pressure gradient and axial velocity are…

Fluid Dynamics · Physics 2010-06-04 J. C. Misra , S. Maiti , G. C. Shit

Ion channels are proteins with a hole down the middle embedded in cell membranes. Membranes form insulating structures and the channels through them allow and control the movement of charged particles, spherical ions, mostly Na+, K+, Ca++,…

Biomolecules · Quantitative Biology 2015-05-11 Bob Eisenberg

Recently a new theory for the transport of energetic particles across a mean magnetic field was presented. Compared to other non-linear theories the new approach has the advantage that it provides a full time-dependent description of the…

Plasma Physics · Physics 2017-09-20 Jordan Lasuik , Andreas Shalchi

We consider single particle and polymer translocation where the frictional properties experienced from the environment are changing in time. This work is motivated by the interesting frequency responsive behaviour observed when a polymer is…

Soft Condensed Matter · Physics 2012-12-06 Jack A. Cohen , Abhishek Chaudhuri , Ramin Golestanian

We investigate the outflux of ions through the channels in a cell membrane. The channels undergo an open/close cycle according to a periodic schedule. Our study is based both on theoretical considerations relying on homogenization theory,…

Analysis of PDEs · Mathematics 2014-11-21 D. Andreucci , D. Bellaveglia , E. N. M. Cirillo

Many biological and artificial transport channels function without direct input of metabolic energy during a transport event and without structural rearrangements involving transitions from a 'closed' to an 'open' state. Nevertheless, such…

Subcellular Processes · Quantitative Biology 2009-11-13 Anton Zilman
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