Related papers: The reliability of a nutritional meta-analysis stu…
In systematic reviews and meta-analysis, researchers often pool the results of the sample mean and standard deviation from a set of similar clinical trials. A number of the trials, however, reported the study using the median, the minimum…
Context: Conducting experiments is central to research machine learning research to benchmark, evaluate and compare learning algorithms. Consequently it is important we conduct reliable, trustworthy experiments. Objective: We investigate…
Metabolic Syndrome (MetS) is a cluster of interrelated risk factors that significantly increases the risk of cardiovascular diseases and type 2 diabetes. Despite its global prevalence, accurate prediction of MetS remains challenging due to…
In the machine learning culture, an independent test set is required for proper model verification. Failures in model verification, including test set omission and test set leakage, make it impossible to know whether or not a trained model…
Meta-analysis is an important tool for combining results from multiple studies and has been widely used in evidence-based medicine for several decades. This paper reports, for the first time, an interesting and valuable paradox in…
Many practical studies rely on hypothesis testing procedures applied to data sets with missing information. An important part of the analysis is to determine the impact of the missing data on the performance of the test, and this can be…
The interplay between mood and eating episodes has been extensively researched, revealing a connection between the two. Previous studies have relied on questionnaires and mobile phone self-reports to investigate the relationship between…
Diagnostic test accuracy studies observe the result of a gold standard procedure that defines the presence or absence of a disease and the result of a diagnostic test. They typically report the number of true positives, false positives,…
Bernstein fits implemented into R allow another route for Kruskal-Wallis power-study tool development. Monte-Carlo Kruskal-Wallis power studies were compared with measured power, with Monte-Carlo ANOVA equivalent and with an analytical…
Long-form clinical summarization of hospital admissions has real-world significance because of its potential to help both clinicians and patients. The faithfulness of summaries is critical to their safe usage in clinical settings. To better…
Sustained high levels of blood glucose in type 2 diabetes (T2DM) can have disastrous long-term health consequences. An essential component of clinical interventions for T2DM is monitoring dietary intake to keep plasma glucose levels within…
Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is most commonly used. In this paper, we first illustrate with a simple example that the $I^2$ statistic is heavily…
Biological sequencing data consist of read counts, e.g. of specified taxa and often exhibit sparsity (zero-count inflation) and overdispersion (extra-Poisson variability). As most sequencing techniques provide an arbitrary total count,…
Past research has shown the benefits of food journaling in promoting mindful eating and healthier food choices. However, the links between journaling and healthy eating have not been thoroughly examined. Beyond caloric restriction, do…
Many digital platforms offer advertisers experimentation tools like Meta's Lift and A/B tests to optimize their ad campaigns. Lift tests compare outcomes between users eligible to see ads versus users in a no-ad control group. In contrast,…
Consumption of diets with low glycemic impact is highly recommended for diabetics and pre-diabetics as it helps maintain their blood glucose levels. However, laboratory analysis of dietary glycemic potency is time-consuming and expensive.…
In clinical trials, it is often of interest to understand the principal causal effect (PCE), the average treatment effect for a principal stratum (a subset of patients defined by the potential outcomes of one or more post-baseline…
Clinical trials are common in medical research where multiple non-Gaussian responses and time-dependent observations are frequent. The analysis of data from these studies requires statistical modeling techniques that take these…
Meta-analysis is a statistical method used in evidence synthesis for combining, analyzing and summarizing studies that have the same target endpoint and aims to derive a pooled quantitative estimate using fixed and random effects models or…
The current regulatory paradigm is that PM2.5, over time causes lung cancer. This claim is based on cohort studies and meta-analysis that use cohort studies as their base studies. There is a need to evaluate the reliability of this causal…