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Probabilistic graphical modeling (PGM) provides a framework for formulating an interpretable generative process of data and expressing uncertainty about unknowns, but it lacks flexibility. Deep learning (DL) is an alternative framework for…

Machine Learning · Statistics 2021-04-27 Adji B. Dieng

Deep learning-based graph generation approaches have remarkable capacities for graph data modeling, allowing them to solve a wide range of real-world problems. Making these methods able to consider different conditions during the generation…

Machine Learning · Computer Science 2023-01-11 Faezeh Faez , Negin Hashemi Dijujin , Mahdieh Soleymani Baghshah , Hamid R. Rabiee

Group testing, a problem with diverse applications across multiple disciplines, traditionally assumes independence across nodes' states. Recent research, however, focuses on real-world scenarios that often involve correlations among nodes,…

Information Theory · Computer Science 2025-04-02 Hesam Nikpey , Saswati Sarkar , Shirin Saeedi Bidokhti

Causal graph recovery is traditionally done using statistical estimation-based methods or based on individual's knowledge about variables of interests. They often suffer from data collection biases and limitations of individuals' knowledge.…

Computation and Language · Computer Science 2024-06-19 Yuzhe Zhang , Yipeng Zhang , Yidong Gan , Lina Yao , Chen Wang

Genome-scale gene networks contain regulatory genes called hubs that have many interaction partners. These genes usually play an essential role in gene regulation and cellular processes. Despite recent advancements in high-throughput…

Quantitative Methods · Quantitative Biology 2017-10-06 Nurgazy Sulaimanov , Sunil Kumar , Frédéric Burdet , Mark Ibberson , Marco Pagni , Heinz Koeppl

This work focuses on the problem of multi-label learning with missing labels (MLML), which aims to label each test instance with multiple class labels given training instances that have an incomplete/partial set of these labels. The key…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Baoyuan Wu , Fan Jia , Wei Liu , Bernard Ghanem , Siwei Lyu

Integrative network modeling of data arising from multiple genomic platforms provides insight into the holistic picture of the interactive system, as well as the flow of information across many disease domains including cancer. The basic…

Methodology · Statistics 2020-02-18 Min Jin Ha , Francesco Stingo , Veerabhadran Baladandayuthapani

We present a new, systematic approach for analyzing network topologies. We first introduce the dK-series of probability distributions specifying all degree correlations within d-sized subgraphs of a given graph G. Increasing values of d…

Networking and Internet Architecture · Computer Science 2008-04-16 Priya Mahadevan , Dmitri Krioukov , Kevin Fall , Amin Vahdat

Learning causal relations from observational data is a fundamental problem with wide-ranging applications across many fields. Constraint-based methods infer the underlying causal structure by performing conditional independence tests.…

Machine Learning · Computer Science 2026-03-24 Marc Franquesa Monés , Jiaqi Zhang , Caroline Uhler

Predicting genetic perturbations enables the identification of potentially crucial genes prior to wet-lab experiments, significantly improving overall experimental efficiency. Since genes are the foundation of cellular life, building gene…

Quantitative Methods · Quantitative Biology 2025-05-09 Changxi Chi , Jun Xia , Jingbo Zhou , Jiabei Cheng , Chang Yu , Stan Z. Li

Neural networks are suggested for learning a map from $d$-dimensional samples with any underlying dependence structure to multivariate uniformity in $d'$ dimensions. This map, termed DecoupleNet, is used for dependence model assessment and…

Machine Learning · Statistics 2022-10-06 Marius Hofert , Avinash Prasad , Mu Zhu

This study investigates the generation of high-quality synthetic categorical data, such as survey data, using causal graph models. Generating synthetic data aims not only to create a variety of data for training the models but also to…

Artificial Intelligence · Computer Science 2025-04-17 Olha Shaposhnyk , Noor Abid , Mouri Zakir , Svetlana Yanushkevich

Uniform sampling from graphical realizations of a given degree sequence is a fundamental component in simulation-based measurements of network observables, with applications ranging from epidemics, through social networks to Internet…

Physics and Society · Physics 2010-04-14 Charo I. Del Genio , Hyunju Kim , Zoltan Toroczkai , Kevin E. Bassler

Constructing gene regulatory networks is a fundamental task in systems biology. We introduce a Gaussian reciprocal graphical model for inference about gene regulatory relationships by integrating mRNA gene expression and DNA level…

Methodology · Statistics 2016-07-26 Yang Ni , Yuan Ji , Peter Mueller

The future astronomical imaging surveys are set to provide precise constraints on cosmological parameters, such as dark energy. However, production of synthetic data for these surveys, to test and validate analysis methods, suffers from a…

A major task in genetic studies is to identify genes related to human diseases and traits to understand functional characteristics of genetic mutations and enhance patient diagnosis. Besides marginal analyses of individual genes,…

Methodology · Statistics 2021-11-09 Jin Jin , Yue Wang

A large offspring number diploid biparental multilocus population model of Moran type is our object of study. At each timestep, a pair of diploid individuals drawn uniformly at random contribute offspring to the population. The number of…

Populations and Evolution · Quantitative Biology 2012-10-31 Matthias Birkner , Jochen Blath , Bjarki Eldon

Identifying differences in networks has become a canonical problem in many biological applications. Here, we focus on testing whether two Gaussian graphical models are the same. Existing methods try to accomplish this goal by either…

Methodology · Statistics 2019-10-01 Sen Zhao , Stephen Ottinger , Suzanne Peck , Christine Mac Donald , Ali Shojaie

Fitting mixed models to complex survey data is a challenging problem. Most methods in the literature, including the most widely used one, require a close relationship between the model structure and the survey design. In this paper we…

Methodology · Statistics 2023-11-23 Thomas Lumley , Xudong Huang

Entailment Graphs (EGs) have been constructed based on extracted corpora as a strong and explainable form to indicate context-independent entailment relations in natural languages. However, EGs built by previous methods often suffer from…

Computation and Language · Computer Science 2023-06-08 Zhibin Chen , Yansong Feng , Dongyan Zhao