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Molecular simulations and biophysical experiments can be used to provide independent and complementary insights into the molecular origin of biological processes. A particularly useful strategy is to use molecular simulations as a modelling…

Chemical Physics · Physics 2019-12-10 Simone Orioli , Andreas Haahr Larsen , Sandro Bottaro , Kresten Lindorff-Larsen

Nonlinear plant-scale interactions controlling the soil-water balance are generally not valid at larger spatial scales due to spatial heterogeneity in rainfall and vegetation type. The relationships between spatially averaged variables are…

Many organisms live in populations structured by space and by class, exhibit plastic responses to their social partners, and are subject to non-additive ecological and fitness effects. Social evolution theory has long recognized that all of…

Populations and Evolution · Quantitative Biology 2014-04-24 Jeremy Van Cleve , Erol Akçay

The ability to directly record human face-to-face interactions increasingly enables the development of detailed data-driven models for the spread of directly transmitted infectious diseases at the scale of individuals. Complete coverage of…

Inferring the processes underlying the emergence of observed patterns is a key challenge in theoretical ecology. Much effort has been made in the past decades to collect extensive and detailed information about the spatial distribution of…

Statistical Mechanics · Physics 2021-01-21 P. Villegas , A. Cavagna , M. Cencini , H. Fort , T. S. Grigera

In the last two decades, considerable research has been devoted to a phenomenon known as spatial confounding. Spatial confounding is thought to occur when there is multicollinearity between a covariate and the random effect in a spatial…

Methodology · Statistics 2024-06-25 Kori Khan , Candace Berrett

Neutral models, in which individual agents with equal fitness undergo a birth-death-mutation process, are very popular in population genetics and community ecology. Usually these models are applied to populations and communities with…

Populations and Evolution · Quantitative Biology 2016-06-10 Matan Danino , Yahav Shem-Tov , Nadav M. Shnerb

While fields like Artificial Life have made huge strides in quantifying the mechanisms that distinguish living systems from non-living ones, particular mechanisms remain difficult to reproduce in silico. Known as open-endedness, we've been…

Biological Physics · Physics 2024-07-18 Alyssa M Adams , Eliott Jacopin , Praful Gagrani , Olaf Witkowski

The application of state-of-the-art spatial econometric models requires that the information about the spatial coordinates of statistical units is completely accurate, which is usually the case in the context of areal data. With…

Methodology · Statistics 2019-09-06 Giuseppe Arbia , Maria Michela Dickson , Giuseppe Espa , Diego Giuliani , Flavio Santi

Spatial structure and species interactions jointly shape the dynamics and biodiversity of ecological systems, yet most theoretical models either neglect spatial heterogeneity or sacrifice analytical tractability. Here, we provide a unified…

Populations and Evolution · Quantitative Biology 2026-05-08 Davide Bernardi , Alice Doimo , Giorgio Nicoletti , Prajwal Padmanabha , Andrea Rinaldo , Samir Suweis , Sandro Azaele , Amos Maritan

Evolutionary and ecosystem dynamics are often treated as different processes --operating at separate timescales-- even if evidence reveals that rapid evolutionary changes can feed back into ecological interactions. A recent long-term field…

Populations and Evolution · Quantitative Biology 2018-10-04 Paula Villa Martín , Jorge Hidalgo , Rafael Rubio de Casas , Miguel A. Muñoz

Estimating causal effects from observational data is not always possible due to confounding. Identifying a set of appropriate covariates (adjustment set) and adjusting for their influence can remove confounding bias; however, such a set is…

Methodology · Statistics 2020-11-19 Sofia Triantafillou , Gregory Cooper

Understanding the relationship between complexity and stability in large dynamical systems -- such as ecosystems -- remains a key open question in complexity theory which has inspired a rich body of work developed over more than fifty…

Populations and Evolution · Quantitative Biology 2021-07-14 Yvonne Krumbeck , Qian Yang , George W. A. Constable , Tim Rogers

In a spatial-temporal model, structural change and/or spatial heterogeneity can easily affect estimation of parameters. Following the spatial-temporal model in [1], we develop a nonparametric procedure for test-ing the presence of…

Methodology · Statistics 2021-07-07 Ruby Anne E. Lemence , Erniel B. Barrios

Joint modeling of spatially-oriented dependent variables is commonplace in the environmental sciences, where scientists seek to estimate the relationships among a set of environmental outcomes accounting for dependence among these outcomes…

Methodology · Statistics 2021-03-22 Lu Zhang , Sudipto Banerjee , Andrew O. Finley

Main aim of this topical issue is to report recent advances in noisy nonequilibrium processes useful to describe the dynamics of ecological systems and to address the mechanisms of spatio-temporal pattern formation in ecology both from the…

Biological Physics · Physics 2009-11-13 Astero Provata , Igor M. Sokolov , Bernardo Spagnolo

Estimation of social influence in networks can be substantially biased in observational studies due to homophily and network correlation in exposure to exogenous events. Randomized experiments, in which the researcher intervenes in the…

Social and Information Networks · Computer Science 2017-09-28 Sean J. Taylor , Dean Eckles

Biochemistry, ecology, and neuroscience are examples of prominent fields aiming at describing interacting systems that exhibit non-trivial couplings to complex, ever-changing environments. We have recently shown that linear interactions and…

Statistical Mechanics · Physics 2022-08-10 Giorgio Nicoletti , Daniel Maria Busiello

Correlations between two variables of a high-dimensional system can be indicative of an underlying interaction, but can also result from indirect effects. Inverse Ising inference is a method to distinguish one from the other. Essentially,…

Populations and Evolution · Quantitative Biology 2014-12-10 Benedikt Obermayer , Erel Levine

A central feature of complex systems is the relevance and entanglement of different levels of description. For instance, the dynamics of ecosystems can be alternatively described in terms of large ecological processes and classes of…

Populations and Evolution · Quantitative Biology 2025-10-06 Juan Giral Martínez , Silvia de Monte , Matthieu Barbier