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Traditional functional connectivity based on functional magnetic resonance imaging (fMRI) can only capture pairwise interactions between brain regions. Hypergraphs, which reveal high-order relationships among multiple brain regions, have…

Neurons and Cognition · Quantitative Biology 2025-05-20 Wenqi Hu , Xuerui Su , Guanliang Li , Yidi Pan , Aijing Lin

In many domains such as healthcare or finance, data often come in different assays or measurement modalities, with features in each assay having a common theme. Simply concatenating these assays together and performing prediction can be…

Methodology · Statistics 2018-07-17 J. Kenneth Tay , Robert Tibshirani

As with the development of the IT technologies, the amount of accumulated data is also increasing. Thus the role of data mining comes into picture. Association rule mining becomes one of the significant responsibilities of descriptive…

Databases · Computer Science 2014-02-11 Prof. Paresh Tanna , Dr. Yogesh Ghodasara

Causal discovery aims to infer causal relationships among variables from observational data, typically represented by a directed acyclic graph (DAG). Most existing methods assume independent and identically distributed observations, an…

Methodology · Statistics 2026-03-27 Alex Chen , Qing Zhou

Association rule mining is intended for searching for the relationships between attributes in transaction databases. The whole process of rule discovery is very complex, and involves pre-processing techniques, a rule mining step, and…

Databases · Computer Science 2023-02-27 Iztok Fister , Iztok Fister , Dušan Fister , Vili Podgorelec , Sancho Salcedo-Sanz

Learning from multiple-relational data which contains noise, ambiguities, or duplicate entities is essential to a wide range of applications such as statistical inference based on Web Linked Data, recommender systems, computational biology,…

Machine Learning · Statistics 2016-04-05 Lucas Drumond , Ernesto Diaz-Aviles , Lars Schmidt-Thieme

There are large amounts of transactional data which showed consumer shopping cart at a store that sells more than 150 types of products. In this case, the company is utilizing these data in making business action. In previous studies, the…

Databases · Computer Science 2024-03-08 Feri Sulianta , Laksana Eka Angga , Thee Houw Liong

The joint analysis of biomedical data in Alzheimer's Disease (AD) is important for better clinical diagnosis and to understand the relationship between biomarkers. However, jointly accounting for heterogeneous measures poses important…

Methodology · Statistics 2018-08-14 Luigi Antelmi , Nicholas Ayache , Philippe Robert , Marco Lorenzi

Internet data has surfaced as a primary source for investigation of different aspects of human behavior. A crucial step in such studies is finding a suitable cohort (i.e., a set of users) that shares a common trait of interest to…

Information Retrieval · Computer Science 2018-05-16 Luca Soldaini , Elad Yom-Tov

We propose new parametric frameworks of regression analysis with the conditional mode of a bounded response as the focal point of interest. Covariate effects estimation and prediction based on the maximum likelihood method under two new…

Methodology · Statistics 2020-06-22 Haiming Zhou , Xianzheng Huang

There are several existing algorithms that under appropriate assumptions can reliably identify a subset of the underlying causal relationships from observational data. This paper introduces the first computationally feasible score-based…

Artificial Intelligence · Computer Science 2012-07-02 Subramani Mani , Peter L. Spirtes , Gregory F. Cooper

Modern biomedical data mining requires feature selection methods that can (1) be applied to large scale feature spaces (e.g. `omics' data), (2) function in noisy problems, (3) detect complex patterns of association (e.g. gene-gene…

Machine Learning · Computer Science 2018-04-04 Ryan J. Urbanowicz , Randal S. Olson , Peter Schmitt , Melissa Meeker , Jason H. Moore

This paper presents algorithm for missing values imputation in categorical data. The algorithm is based on using association rules and is presented in three variants. Experimental shows better accuracy of missing values imputation using the…

Machine Learning · Computer Science 2012-11-09 Jiří Kaiser

Machine Learning (ML) algorithms are vital for supporting clinical decision-making in biomedical informatics. However, their predictive performance can vary across demographic groups, often due to the underrepresentation of historically…

Machine Learning · Computer Science 2025-03-04 Ioannis Bilionis , Ricardo C. Berrios , Luis Fernandez-Luque , Carlos Castillo

One of the most important challenges in the analysis of high-throughput genetic data is the development of efficient computational methods to identify statistically significant Single Nucleotide Polymorphisms (SNPs). Genome-wide association…

In domains where transparency and trustworthiness are crucial, such as healthcare, rule-based systems are widely used and often preferred over black-box models for decision support systems due to their inherent interpretability. However, as…

Machine Learning · Computer Science 2025-06-18 Christel Sirocchi , Damiano Verda

Neural embedding-based machine learning models have shown promise for predicting novel links in biomedical knowledge graphs. Unfortunately, their practical utility is diminished by their lack of interpretability. Recently, the fully…

Machine Learning · Computer Science 2020-12-11 Simon Ott , Laura Graf , Asan Agibetov , Christian Meilicke , Matthias Samwald

Coronary artery disease remains one of the leading causes of mortality globally. Despite advances in revascularization treatments like PCI and CABG, postoperative stroke is inevitable. This study aims to develop and evaluate a sophisticated…

Machine Learning · Computer Science 2025-03-18 Haonan Pan , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

The discovery of causal relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we…

Machine Learning · Computer Science 2023-04-26 Payam Dibaeinia , Saurabh Sinha

Background/aims: While randomized controlled trials are the gold standard for measuring causal effects, robust conclusions about causal relationships can be obtained using data from observational studies if proper statistical techniques are…