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Biochemical networks are used in computational biology, to model the static and dynamical details of systems involved in cell signaling, metabolism, and regulation of gene expression. Parametric and structural uncertainty, as well as…

Molecular Networks · Quantitative Biology 2014-10-15 Ovidiu Radulescu , Alexander N. Gorban , Andrei Zinovyev , Vincent Noel

We consider the problem of optimizing the interconnection graphs of complex networks to promote synchronization. When traditional optimization methods are inapplicable, due to uncertain or unknown node dynamics, we propose a data-driven…

Systems and Control · Electrical Eng. & Systems 2023-09-29 Marco Coraggio , Mario di Bernardo

From autonomous driving to package delivery, ensuring safe yet efficient multi-agent interaction is challenging as the interaction dynamics are influenced by hard-to-model factors such as social norms and contextual cues. Understanding…

Systems and Control · Electrical Eng. & Systems 2026-03-11 Isaac Remy , David Fridovich-Keil , Karen Leung

Multienzyme cascaded reactions are widely utilized because they can generate value-added biomaterials and biodevices from simple raw materials. However, how to promote the catalytic efficiency and synergistic effect of the multienzyme…

Biological Physics · Physics 2021-01-27 Zhexu Xi

Discovering governing equations from data is crucial for understanding complex systems in many diverse fields from science to engineering. Yet, there still is a lack of versatile computational toolbox to deal with this long standing…

Chaotic Dynamics · Physics 2026-05-15 Chengzuo Zhuge , Zheng Jiang , Zhefan Xu , Wei Chen

Autonomous driving algorithms rely heavily on learning-based models, which require large datasets for training. However, there is often a large amount of redundant information in these datasets, while collecting and processing these…

Machine Learning · Computer Science 2023-06-27 Jianyu Lai , Zexuan Jia , Boao Li

Molecular dynamics simulations hold great promise for providing insight into the microscopic behavior of complex molecular systems. However, their effectiveness is often constrained by long timescales associated with rare events. Enhanced…

Computational Physics · Physics 2026-03-03 Kai Zhu , Enrico Trizio , Jintu Zhang , Renling Hu , Linlong Jiang , Tingjun Hou , Luigi Bonati

Information theory and the framework of information dynamics have been used to provide tools to characterise complex systems. In particular, we are interested in quantifying information storage, information modification and information…

Information Theory · Computer Science 2013-03-25 Oliver Obst , Joschka Boedecker , Benedikt Schmidt , Minoru Asada

This essay provides a critical overview of the mathematical kinetic theory of active particles, which is used to model and study collective systems consisting of interacting living entities, such as those involved in behavior and evolution.…

Physics and Society · Physics 2025-10-17 Marina Dolfin , Leone Leonida

The use of dialogue systems as a medium for human-machine interaction is an increasingly prevalent paradigm. A growing number of dialogue systems use conversation strategies that are learned from large datasets. There are well documented…

Computation and Language · Computer Science 2017-11-27 Peter Henderson , Koustuv Sinha , Nicolas Angelard-Gontier , Nan Rosemary Ke , Genevieve Fried , Ryan Lowe , Joelle Pineau

Progress in the creation of large scale, artificial quantum coherent structures demands the investigation of their nonequilibrium dynamics when strong interactions, even between remote parts, are non-perturbative. Analysis of multiparticle…

Training a team to complete a complex task via multi-agent reinforcement learning can be difficult due to challenges such as policy search in a large joint policy space, and non-stationarity caused by mutually adapting agents. To facilitate…

Multiagent Systems · Computer Science 2024-02-16 Elliot Fosong , Arrasy Rahman , Ignacio Carlucho , Stefano V. Albrecht

We present our preliminary work on a multi-agent system involving the complex human phenomena of identity and dynamic teams. We outline our ongoing experimentation into understanding how these factors can eliminate some of the naive…

Multiagent Systems · Computer Science 2023-01-05 Kyle Tilbury , Jesse Hoey

Traffic jams on roadways, echo chambers on social media, crowds of moving pedestrians, and opinion dynamics during elections are all complex social systems. These applications may seem disparate, but some of the questions that they motivate…

Physics and Society · Physics 2022-10-18 Alexandria Volkening

Infinitesimal contraction analysis, wherein global asymptotic convergence results are obtained from local dynamical properties, has proven to be a powerful tool for applications in biological, mechanical, and transportation systems. Thus…

Dynamical Systems · Mathematics 2018-04-12 Samuel A Burden , Samuel D Coogan

The rise of Agent AI and Large Language Model-powered Multi-Agent Systems (LLM-MAS) has underscored the need for responsible and dependable system operation. Tools like LangChain and Retrieval-Augmented Generation have expanded LLM…

Multiagent Systems · Computer Science 2025-02-05 Jinwei Hu , Yi Dong , Shuang Ao , Zhuoyun Li , Boxuan Wang , Lokesh Singh , Guangliang Cheng , Sarvapali D. Ramchurn , Xiaowei Huang

A distributed stochastic optimal control solution is presented for cooperative multi-agent systems. The network of agents is partitioned into multiple factorial subsystems, each of which consists of a central agent and neighboring agents.…

Systems and Control · Electrical Eng. & Systems 2021-03-23 Neng Wan , Aditya Gahlawat , Naira Hovakimyan , Evangelos A. Theodorou , Petros G. Voulgaris

We consider local bifurcations of equilibria in dynamical systems arising from chemical reaction networks with mass action kinetics. In particular, given any mass action network admitting a local bifurcation of equilibria, assuming only a…

Dynamical Systems · Mathematics 2025-05-20 Murad Banaji , Balázs Boros , Josef Hofbauer

A complex system is a system composed of many interacting parts, often called agents, which displays collective behavior that does not follow trivially from the behaviors of the individual parts. Examples include condensed matter systems,…

Statistical Mechanics · Physics 2011-12-08 M. E. J. Newman

Microservices bring various benefits to software systems. They also bring decentralization and lose coupling across self-contained system parts. Since these systems likely evolve in a decentralized manner, they need to be monitored to…

Software Engineering · Computer Science 2022-07-07 Abdullah Al Maruf , Alexander Bakhtin , Tomas Cerny , Davide Taibi
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