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The bacterial flagellar motor drives the rotation of flagellar filaments and enables many species of bacteria to swim. Torque is generated by interaction of stator units, anchored to the peptidoglycan cell wall, with the rotor. Recent…

Subcellular Processes · Quantitative Biology 2010-08-18 G. Meacci , Y. Tu

A finite cycle time information engine based on a two-level system in contact with a thermal reservoir is studied analytically. The model for the engine incorporates an error in measuring the system's state and time delay between the…

Statistical Mechanics · Physics 2024-05-13 Kiran V , Toby Joseph

Time plays a fundamental role in our ability to make sense of the physical laws in the world around us. The nature of time has puzzled people -- from the ancient Greeks to the present day -- resulting in a long running debate between…

Quantum Physics · Physics 2021-09-23 Sergii Strelchuk , Mischa P. Woods

Chemical affinities are responsible for driving active matter systems out of equilibrium. At the nano-scale, molecular machines interact with the surrounding environment and are subjected to external forces. The mechano-chemical coupling…

Soft Condensed Matter · Physics 2025-01-03 Michalis Chatzittofi , Jaime Agudo-Canalejo , Ramin Golestanian

A simple model for the reaction-driven propulsion of a small device is proposed as a model for (part of) a molecular machine in aqueous media. Motion of the device is driven by an asymmetric distribution of reaction products. The propulsive…

Soft Condensed Matter · Physics 2009-11-13 Ramin Golestanian , Tanniemola B. Liverpool , Armand Ajdari

The function of the organism hinges on the performance of its information-processing networks, which convey information via molecular recognition. Many paths within these networks utilize molecular codebooks, such as the genetic code, to…

Biomolecules · Quantitative Biology 2010-07-27 Tsvi Tlusty

Biological molecular machines are proteins that operate under isothermal conditions hence are referred to as free energy transducers. They can be formally considered as enzymes that simultaneously catalyze two chemical reactions: the free…

Biological Physics · Physics 2014-02-05 Michal Kurzynski , Mieczyslaw Torchala , Przemyslaw Chelminiak

The work done by a parallel plate capacitor is evaluated when the plate separation is changed. Two cases are considered: 1) the capacitor has a constant charge; 2) the capacitor is at constant voltage. The net work is calculated when the…

General Physics · Physics 2012-09-28 E. N. Miranda

Brownian clocks are biomolecular networks that can count time. A paradigmatic example are proteins that go through a cycle thus regulating some oscillatory behaviour in a living system. Typically, such a cycle requires free energy often…

Statistical Mechanics · Physics 2017-01-20 Andre C Barato , Udo Seifert

Simulations can help unravel the complicated ways in which molecular structure determines function. Here, we use molecular simulations to show how slight alterations of a molecular motor's structure can cause the motor's typical dynamical…

Statistical Mechanics · Physics 2023-08-21 Alex Albaugh , Geyao Gu , Todd R. Gingrich

Isothermal information engines operate by extracting net work from a single heat bath through measurement and feedback control. In this work, we analyze a realistic active Szilard engine operating on a single active particle by means of…

Statistical Mechanics · Physics 2025-05-15 Luca Cocconi , Paolo Malgaretti , Holger Stark

Molecular Communication (MC) is a communication strategy that uses molecules as carriers of information, and is widely used by biological cells. As an interdisciplinary topic, it has been studied by biologists, communication theorists and a…

Information Theory · Computer Science 2016-12-13 Amin Gohari , Mahtab Mirmohseni , Masoumeh Nasiri-Kenari

In a molecular communication network, transmitters and receivers communicate by using signalling molecules. At the receivers, the signalling molecules react, via a chain of chemical reactions, to produce output molecules. The counts of…

Molecular Networks · Quantitative Biology 2020-07-23 Chun Tung Chou

A moldable job is a job that can be executed on an arbitrary number of processors, and whose processing time depends on the number of processors allotted to it. A moldable job is monotone if its work doesn't decrease for an increasing…

Data Structures and Algorithms · Computer Science 2018-01-09 Klaus Jansen , Felix Land

Dynamics of molecular motors that move along linear lattices and interact with them via reversible destruction of specific lattice bonds is investigated theoretically by analyzing exactly solvable discrete-state ``burnt-bridge'' models.…

Soft Condensed Matter · Physics 2009-11-13 Max N. Artyomov , Alexander Yu. Morozov , Anatoly B. Kolomeisky

We analyze a simple stochastic model to describe motor molecules which cooperate in large groups and present a physical mechanism which can lead to oscillatory motion if the motors are elastically coupled to their environment. Beyond a…

Soft Condensed Matter · Physics 2009-10-28 Frank Julicher , Jacques Prost

We discuss effects of the stepping kinetics of molecular motors on their traffic behavior on crowded filaments using a simple two-state chemomechanical cycle. While the general traffic behavior is quite robust with respect to the detailed…

Statistical Mechanics · Physics 2008-10-10 Stefan Klumpp , Yan Chai , Reinhard Lipowsky

Intracellular transport is based on molecular motors that pull cargos along cytoskeletal filaments. One motor species always moves in one direction, e.g. conventional kinesin moves to the microtubule plus end, while cytoplasmic dynein moves…

Subcellular Processes · Quantitative Biology 2008-07-04 Melanie J. I. Müller , Stefan Klumpp , Reinhard Lipowsky

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

We study the energestics of a thermal motor driven by temperature differences, which consists of Brownian particles moving in a sawtooth potential with an external load where the viscous medium is alternately in contact with hot and cold…

Biological Physics · Physics 2009-11-11 Baoquan Ai , Liqiu Wang , Huizhang Xie , Lianggang Liu
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