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Detection limit (DL) has become an increasingly ubiquitous issue in statistical analyses of biomedical studies, such as cytokine, metabolite and protein analysis. In regression analysis, if an explanatory variable is left-censored due to…

Inferring a cause from its effect using observed time series data is a major challenge in natural and social sciences. Assuming the effect is generated by the cause trough a linear system, we propose a new approach based on the hypothesis…

Artificial Intelligence · Computer Science 2015-03-05 Naji Shajarisales , Dominik Janzing , Bernhard Shoelkopf , Michel Besserve

Real-world problems, for example in climate applications, often require causal reasoning on spatially gridded time series data or data with comparable structure. While the underlying system is often believed to behave similarly at different…

Machine Learning · Computer Science 2026-02-16 Martin Rabel , Jakob Runge

We propose a new method of discovering causal relationships in temporal data based on the notion of causal compression. To this end, we adopt the Pearlian graph setting and the directed information as an information theoretic tool for…

Machine Learning · Statistics 2016-11-02 Aleksander Wieczorek , Volker Roth

We introduce an approach which allows detecting causal relationships between variables for which the time evolution is available. Causality is assessed by a variational scheme based on the Information Imbalance of distance ranks, a…

Methodology · Statistics 2024-05-07 Vittorio Del Tatto , Gianfranco Fortunato , Domenica Bueti , Alessandro Laio

The power of sparse signal modeling with learned over-complete dictionaries has been demonstrated in a variety of applications and fields, from signal processing to statistical inference and machine learning. However, the statistical…

Information Theory · Computer Science 2017-04-26 Ignacio Ramírez , Guillermo Sapiro

A basic principle in the design of observational studies is to approximate the randomized experiment that would have been conducted under controlled circumstances. Now, linear regression models are commonly used to analyze observational…

Methodology · Statistics 2022-07-08 Ambarish Chattopadhyay , Jose R. Zubizarreta

Entropic causal inference is a framework for inferring the causal direction between two categorical variables from observational data. The central assumption is that the amount of unobserved randomness in the system is not too large. This…

Machine Learning · Statistics 2021-01-12 Spencer Compton , Murat Kocaoglu , Kristjan Greenewald , Dmitriy Katz

In settings where Machine Learning (ML) algorithms automate or inform consequential decisions about people, individual decision subjects are often incentivized to strategically modify their observable attributes to receive more favorable…

Machine Learning · Computer Science 2022-06-10 Keegan Harris , Daniel Ngo , Logan Stapleton , Hoda Heidari , Zhiwei Steven Wu

Unlike parametric regression, machine learning (ML) methods do not generally require precise knowledge of the true data generating mechanisms. As such, numerous authors have advocated for ML methods to estimate causal effects.…

Methodology · Statistics 2020-05-15 Ashley I Naimi , Alan E Mishler , Edward H Kennedy

Whether a variable is the cause of another, or simply associated with it, is often an important scientific question. Causal Inference is the name associated with the body of techniques for addressing that question in a statistical setting.…

Applications · Statistics 2025-06-25 Caren Marzban , Yikun Zhang , Nicholas Bond , Michael Richman

Causal discovery traditionally relies on statistical methods applied to observational data, often requiring large datasets and assumptions about underlying causal structures. Recent advancements in Large Language Models (LLMs) have…

Machine Learning · Computer Science 2025-04-16 Yuni Susanti , Michael Färber

Discovering causal relations is fundamental to reasoning and intelligence. In particular, observational causal discovery algorithms estimate the cause-effect relation between two random entities $X$ and $Y$, given $n$ samples from $P(X,Y)$.…

Machine Learning · Statistics 2017-02-24 Mateo Rojas-Carulla , Marco Baroni , David Lopez-Paz

Estimating individualized treatment effects from observational data presents a persistent challenge due to unmeasured confounding and structural bias. Causal Machine Learning (causal ML) methods, such as causal trees and doubly robust…

Machine Learning · Computer Science 2025-08-12 Po-Han Lee , Yu-Cheng Lin , Chan-Tung Ku , Chan Hsu , Pei-Cing Huang , Ping-Hsun Wu , Yihuang Kang

Latent variable models provide a powerful framework for incorporating and inferring unobserved factors in observational data. In causal inference, they help account for hidden factors influencing treatment or outcome, thereby addressing…

Machine Learning · Computer Science 2025-08-29 Tetsuro Morimura , Tatsushi Oka , Yugo Suzuki , Daisuke Moriwaki

Discovering causal relationships from observational data, particularly in the presence of latent variables, poses a challenging problem. While current local structure learning methods have proven effective and efficient when the focus lies…

Machine Learning · Computer Science 2024-06-07 Feng Xie , Zheng Li , Peng Wu , Yan Zeng , Chunchen Liu , Zhi Geng

Local causal discovery is of great practical significance, as there are often situations where the discovery of the global causal structure is unnecessary, and the interest lies solely on a single target variable. Most existing local…

Machine Learning · Computer Science 2024-03-25 Haoyue Dai , Ignavier Ng , Yujia Zheng , Zhengqing Gao , Kun Zhang

Causality defines the relationship between cause and effect. In multivariate time series field, this notion allows to characterize the links between several time series considering temporal lags. These phenomena are particularly important…

Methodology · Statistics 2023-06-01 Antonin Arsac , Aurore Lomet , Jean-Philippe Poli

Inferring cause-effect relationships from observational data has gained significant attention in recent years, but most methods are limited to scalar random variables. In many important domains, including neuroscience, psychology, social…

Machine Learning · Statistics 2025-06-06 Konstantin Göbler , Tobias Windisch , Mathias Drton

The use of deep neural networks to make high risk decisions creates a need for global and local explanations so that users and experts have confidence in the modeling algorithms. We introduce a novel technique to find global and local…

Machine Learning · Computer Science 2019-08-15 Xochitl Watts , Freddy Lecue
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