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Mixed-integer optimization is at the core of many online decision-making systems that demand frequent updates of decisions in real time. However, due to their combinatorial nature, mixed-integer linear programs (MILPs) can be difficult to…

Optimization and Control · Mathematics 2026-04-21 Shivi Dixit , Rishabh Gupta , Qi Zhang

The design of genome-scale constraint-based metabolic networks has steadily advanced, with an increasing number of successful cases achieving growth-coupled production, in which the biosynthesis of key metabolites is linked to cell growth.…

Molecular Networks · Quantitative Biology 2026-05-19 Yier Ma , Takeyuki Tamura

Cutting planes (cuts) are crucial for solving Mixed Integer Linear Programming (MILP) problems. Advanced MILP solvers typically rely on manually designed heuristic algorithms for cut selection, which require much expert experience and…

Optimization and Control · Mathematics 2024-12-11 Xuefeng Zhang , Liangyu Chen , Zhengfeng Yang , Zhenbing Zeng

Given real numbers whose sum is an integer, we study the problem of finding integers which match these real numbers as closely as possible, in the sense of L^p norm, while preserving the sum. We describe the structure of solutions for this…

Data Structures and Algorithms · Computer Science 2015-01-05 Rama Cont , Massoud Heidari

Exploration of task mappings plays a crucial role in achieving high performance in heterogeneous multi-processor system-on-chip (MPSoC) platforms. The problem of optimally mapping a set of tasks onto a set of given heterogeneous processors…

Performance · Computer Science 2014-07-01 Wei Quan , Andy D. Pimentel

We introduce a problem class we call Polynomial Constraint Satisfaction Problems, or PCSP. Where the usual CSPs from computer science and optimization have real-valued score functions, and partition functions from physics have monomials,…

Discrete Mathematics · Computer Science 2010-01-14 Alexander D. Scott , Gregory B. Sorkin

In the minimum common string partition (MCSP) problem two related input strings are given. "Related" refers to the property that both strings consist of the same set of letters appearing the same number of times in each of the two strings.…

Data Structures and Algorithms · Computer Science 2017-02-02 Christian Blum , Günther R. Raidl

Biclustering is a problem in machine learning and data mining that seeks to group together rows and columns of a dataset according to certain criteria. In this work, we highlight the natural relation that quantum computing models like boson…

Quantum Physics · Physics 2024-05-30 Ajinkya Borle , Ameya Bhave

A new maximum approximate likelihood (ML) estimation algorithm for the mixture of Kent distribution is proposed. The new algorithm is constructed via the BSLM (block successive lower-bound maximization) framework and incorporates manifold…

Computation · Statistics 2017-09-15 Hien D. Nguyen

Motivated by applications in instance selection, we introduce the star discrepancy subset selection problem, which consists of finding a subset of m out of n points that minimizes the star discrepancy. First, we show that this problem is…

Computational Geometry · Computer Science 2022-01-05 François Clèment , Carola Doerr , Luís Paquete

Matrix decomposition is one of the fundamental tools to discover knowledge from big data generated by modern applications. However, it is still inefficient or infeasible to process very big data using such a method in a single machine.…

Machine Learning · Computer Science 2020-02-11 Chihao Zhang , Yang Yang , Wei Zhang , Shihua Zhang

In this paper we propose a new problem of finding the maximal bi-connected partitioning of a graph with a size constraint (MBCPG-SC). With the goal of finding approximate solutions for the MBCPG-SC, a heuristic method is developed based on…

Discrete Mathematics · Computer Science 2016-04-19 Raka Jovanovic , Tatsushi Nishi , Stefan Voss

The maximum graph bisection problem is a well known graph partition problem. The problem has been proven to be NP-hard. In the maximum graph bisection problem it is required that the set of vertices is divided into two partition with equal…

Discrete Mathematics · Computer Science 2015-12-03 Zoran Maksimovic

Coarse-grained (CG) modeling simplifies molecular systems by mapping groups of atoms into representative units. However, traditional CG approaches rely on fixed mapping rules, which limit their ability to handle diverse chemical systems and…

Computational Physics · Physics 2025-09-26 Zhixuan Zhong , Linbo Ma , Jian Jiang

Efficient Maximum Inner Product Search (MIPS) is an important task that has a wide applicability in recommendation systems and classification with a large number of classes. Solutions based on locality-sensitive hashing (LSH) as well as…

Machine Learning · Computer Science 2015-12-01 Alex Auvolat , Sarath Chandar , Pascal Vincent , Hugo Larochelle , Yoshua Bengio

Cluster analysis faces two problems in high dimensions: first, the `curse of dimensionality' that can lead to overfitting and poor generalization performance; and second, the sheer time taken for conventional algorithms to process large…

Quantitative Methods · Quantitative Biology 2013-09-12 Shabnam N. Kadir , Dan F. M. Goodman , Kenneth D. Harris

Machine Reassignment is a challenging problem for constraint programming (CP) and mixed-integer linear programming (MILP) approaches, especially given the size of data centres. The multi-objective version of the Machine Reassignment Problem…

Artificial Intelligence · Computer Science 2021-03-19 Takfarinas Saber , Anthony Ventresque , Joao Marques-Silva , James Thorburn , Liam Murphy

This paper studies the Graph-Connected Clique-Partitioning Problem (GCCP), a clustering optimization model in which units are characterized by both individual and relational data. This problem, introduced by Benati et al. (2017) under the…

Optimization and Control · Mathematics 2021-04-13 Stefano Benati , Diego Ponce , Justo Puerto , Antonio M. Rodríguez-Chía

Large Language Models (LLMs) excel at generating fluent text but struggle to enforce external constraints because they generate tokens sequentially without explicit control mechanisms. GenCP addresses this limitation by combining LLM…

Computation and Language · Computer Science 2025-06-02 Alexandre Bonlarron , Florian Régin , Elisabetta De Maria , Jean-Charles Régin

This article presents the first mixed-integer linear programming (MILP)-based iterative algorithm to solve factorable mixed-integer nonlinear programs (MINLPs) with bounded, differentiable periodic functions to global optimality with an…

Optimization and Control · Mathematics 2025-10-01 Christopher Montez , Sujeevraja Sanjeevi , Kaarthik Sundar