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Culture involves the origination and transmission of ideas, but the conditions in which culture can emerge and evolve are unclear. We constructed and studied a highly simplified neural-network model of these processes. In this model ideas…

Neurons and Cognition · Quantitative Biology 2023-10-16 Kingsley J. A. Cox , Paul R. Adams

In many developmental systems, cells differentiate into a tissue by reading out morphogen concentration fields, a process fundamentally limited by noise. How much can the precision of this process be improved by nonlocal information, e.g.,…

Biological Physics · Physics 2025-12-24 Alex Chen Yi Zhang , Pablo Mateu Hoyos , David Brückner , Gašper Tkačik

The drive to develop artificial neural networks that efficiently utilize resources has generated significant interest in bio-inspired Spiking Neural Networks (SNNs). These networks are particularly attractive due to their potential in…

Neural and Evolutionary Computing · Computer Science 2024-05-28 Lars Graf , Zhe Su , Giacomo Indiveri

Animals can learn efficiently from a single experience and change their future behavior in response. However, in other instances, animals learn very slowly, requiring thousands of experiences. Here I survey tasks involving fast and slow…

Neurons and Cognition · Quantitative Biology 2022-05-05 Markus Meister

The ability to accurately predict the surrounding environment is a foundational principle of intelligence in biological and artificial agents. In recent years, a variety of approaches have been proposed for learning to predict the physical…

Computer Vision and Pattern Recognition · Computer Science 2019-08-01 Alberto Cenzato , Alberto Testolin , Marco Zorzi

Machine learning models often require large datasets and struggle to generalize beyond their training distribution. These limitations pose significant challenges in scientific and engineering contexts, where generating exhaustive datasets…

Chemical Physics · Physics 2025-06-12 Salman N. Salman , Sergey A. Shteingolts , Ron Levie , Dan Mendels

Localized receptive fields -- neurons that are selective for certain contiguous spatiotemporal features of their input -- populate early sensory regions of the mammalian brain. Unsupervised learning algorithms that optimize explicit…

Machine Learning · Computer Science 2025-01-30 Leon Lufkin , Andrew M. Saxe , Erin Grant

Neurons and networks in the cerebral cortex must operate reliably despite multiple sources of noise. To evaluate the impact of both input and output noise, we determine the robustness of single-neuron stimulus selective responses, as well…

Neurons and Cognition · Quantitative Biology 2018-01-24 Ran Rubin , L. F. Abbott , Haim Sompolinsky

In a physical neural system, where storage and processing are intimately intertwined, the rules for adjusting the synaptic weights can only depend on variables that are available locally, such as the activity of the pre- and post-synaptic…

Machine Learning · Computer Science 2016-10-25 Pierre Baldi , Peter Sadowski

Neuronal circuits can learn and replay firing patterns evoked by sequences of sensory stimuli. After training, a brief cue can trigger a spatiotemporal pattern of neural activity similar to that evoked by a learned stimulus sequence.…

Neurons and Cognition · Quantitative Biology 2015-07-03 Alan Veliz-Cuba , Harel Shouval , Kresimir Josic , Zachary P. Kilpatrick

We consider a noise driven network of integrate-and-fire neurons. The network evolves as result of the activities of the neurons following spike-timing-dependent plasticity rules. We apply a self-consistent mean-field theory to the system…

Neurons and Cognition · Quantitative Biology 2010-02-05 Chun-Chung Chen , David Jasnow

Adaptive cognition requires structured internal models of objects and their relations. Predictive neural networks are often proposed to learn such world models, but how these are instantiated and how they support prediction remain unclear.…

Machine Learning · Computer Science 2026-05-11 Linda Ariel Ventura , Victoria Bosch , Tim C Kietzmann , Sushrut Thorat

The interactions between diffusing molecules and membrane-bound receptors drive numerous cellular processes. In this work, we develop a spatial model of molecular interactions with membrane receptors by homogenizing the cell membrane and…

Quantitative Methods · Quantitative Biology 2025-01-24 Anil Cengiz , Sean D Lawley

Neuromodulation plays a fundamental role in the acquisition of new behaviours. Our experimental findings show that, whereas acetylcholine biases hippocampal synaptic plasticity towards depression, the subsequent application of dopamine can…

Neurons and Cognition · Quantitative Biology 2017-10-06 Sara Zannone , Zuzanna Brzosko , Ole Paulsen , Claudia Clopath

How can neural networks learn to efficiently represent complex and high-dimensional inputs via local plasticity mechanisms? Classical models of representation learning assume that input weights are learned via pairwise Hebbian-like…

Neurons and Cognition · Quantitative Biology 2022-10-04 Fabian Alexander Mikulasch , Lucas Rudelt , Viola Priesemann

Biological neural networks exist in physical space where distance influences communication delays: a fundamental coupling between space and time absent in most artificial neural networks. While recent work has separately explored spatial…

Neural and Evolutionary Computing · Computer Science 2026-01-27 Balázs Mészáros , James C. Knight , Danyal Akarca , Thomas Nowotny

We present an unsupervised, local activation-dependent learning rule for intrinsic plasticity (IP) which affects the composition of ion channel conductances for single neurons in a use-dependent way. We use a single-compartment…

Neurons and Cognition · Quantitative Biology 2017-08-29 Gabriele Scheler

Schemas are knowledge structures that can enable rapid learning. Rodent one-shot learning in a multiple paired association navigation task has been postulated to be schema-dependent. We still only poorly understand how schemas,…

Neural and Evolutionary Computing · Computer Science 2024-09-11 M Ganesh Kumar , Cheston Tan , Camilo Libedinsky , Shih-Cheng Yen , Andrew Yong-Yi Tan

Understanding how the brain learns can be advanced by investigating biologically plausible learning rules -- those that obey known biological constraints, such as locality, to serve as valid brain learning models. Yet, many studies overlook…

Neural and Evolutionary Computing · Computer Science 2025-01-13 Weixuan Liu , Xinyue Zhang , Yuhan Helena Liu

The ability to adapt to changing environments and settings is essential for robots acting in dynamic and unstructured environments or working alongside humans with varied abilities or preferences. This work introduces an extremely simple…

Robotics · Computer Science 2022-10-31 Pamela Carreno-Medrano , Dana Kulić , Michael Burke