Related papers: On excited state reaction path in reversibly switc…
In this work, we consider a three-level ladder-type atom driven by a coherent field, inspired by the experimental work of Gasparinetti et al. [Phys. Rev. A 100, 033802 (2019)]. When driven on two-photon resonance, the atom is excited into…
Carbon monoxide (CO) absorption in the sub-damped Lyman-$\alpha$ absorber at redshift $z_{abs} \simeq 2.69$, toward the background quasar SDSS J123714.60+064759.5 (J1237+0647), was investigated for the first time in order to search for a…
Absorption spectroscopy toward high-redshift quasars provides strong constraints on the putative variation of fundamental constants of physics on cosmological time scales. The submillimeter ground-state transitions of methylidyne (CH) and…
Structure-informed protein representation learning is essential for effective protein function annotation and \textit{de novo} design. However, the presence of inherent noise in both crystal and AlphaFold-predicted structures poses…
(abridged) Quasar absorption lines provide a precise test of the assumed constancy of the fundamental constants of physics. We have investigated potential changes in the fine-structure constant, alpha, and the proton-to-electron mass ratio,…
Conformational changes of single proteins are monitored in real time by Forster-type resonance energy transfer, FRET. Two different fluorophores have to be attached to those protein domains, which move during function. The distance between…
We combine the coherent modified Redfield theory (CMRT) with the equation of motion-phase matching approach (PMA) to calculate two-dimensional photon echo spectra for photoactive molecular complexes with an intermediate strength of the…
Ordered protein layers are the subject of active biomedical research for their usually interesting physicochemical properties, e.g. permeability, stiffness and pours structure. In presented work, we focused on layers build of fibrinogen…
We demonstrate two categories of photonic radio frequency (RF) filters based on integrated optical micro-combs. The first one is based on the transversal filtering structure and the second one is based on the channelization technique. The…
Under certain conditions, the dynamics of coarse-grained models of solvated proteins can be described using a Markov state model, which tracks the evolution of populations of configurations. The transition rates among states that appear in…
The biological functions of proteins often depend on dynamic structural ensembles. In this work, we develop a flow-based generative modeling approach for learning and sampling the conformational landscapes of proteins. We repurpose highly…
Domain motions involved in the function of proteins can often be well described as a combination of motions along a handfull of low-frequency modes, that is, with the values of a few normal coordinates. This means that, when the functional…
We present a method by which the degree of longitudinal variation in photonic crystal fibre (PCF) may be characterised through seeded four-wave mixing (FWM). Using an iterative numerical reconstruction, we created a model PCF that displays…
Light-activated drugs are a promising way to localize biological activity and minimize side effects. However, their development is complicated by the numerous photophysical and biological properties that must be simultaneously optimized. To…
Translation is a crucial step in gene expression. During translation, macromolecules called ribosomes "read" the mRNA strand in a sequential manner and produce a corresponding protein. Translation is known to consume most of the cell's…
Determining light shift in Raman-Ramsey interference is important for the development of atomic frequency standards based on a vapor cell. We have accurately calculated light shift in Raman-Ramsey interference using the density-matrix…
A growing number of proteins have been shown to adopt knotted folds. Yet the biological roles and biophysical properties of these knots remain poorly understood. We have used protein engineering and atomic force microscopy to explore…
Inelastic light (Raman) scattering has been used to study electronic excitations and phonon anomalies in detwinned, slightly overdoped YBa$_2$Cu$_3$O$_{6.95}$ and moderately overdoped Y$_{0.85}$Ca$_{0.15}$Ba$_2$Cu$_3$O$_{6.95}$ single…
The ribosomal density along the coding region of the mRNA molecule affect various fundamental intracellular phenomena including: protein production rates, organismal fitness, ribosomal drop off, and co-translational protein folding. Thus,…
Collapsin response mediator protein CRMP2 (gene: DPYSL2) is crucial for neuronal development. The homotetrameric CRMP2 complex is regulated via two mechanisms, first by phosphorylation at, and second by reduction and oxidation of the Cys504…