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We propose an algorithm for generating explicit solutions of multiparametric mixed-integer convex programs to within a given suboptimality tolerance. The algorithm is applicable to a very general class of optimization problems, but is most…

Optimization and Control · Mathematics 2019-06-12 Danylo Malyuta , Behcet Acikmese

The abstract tile assembly model (aTam) is a model of DNA self-assembly. Most of the studies focus on cooperative aTAM where a form of synchronization between the tiles is possible. Simulating Turing machines is achievable in this context.…

Computational Complexity · Computer Science 2026-05-11 Sergiu Ivanov , Damien Regnault

We consider the problem of approximating a two-dimensional shape contour (or curve segment) using discrete assembly systems, which allow to build geometric structures based on limited sets of node and edge types subject to edge length and…

Computational Geometry · Computer Science 2021-02-03 Andreas M. Tillmann , Leif Kobbelt

We present a strict separation between the class of "mismatch free" self-assembly systems and general aTAM systems. Mismatch free systems are those systems in which concurrently grown parts must always agree with each other. Tile…

Computational Geometry · Computer Science 2015-02-20 Florent Becker , Pierre-Étienne Meunier

Experiments have reached a monumental capacity for designing and synthesizing microscopic particles for self-assembly, making it possible to precisely control particle concentrations, shapes, and interactions. However, more physical insight…

Soft Condensed Matter · Physics 2026-02-19 Maximilian C. Hübl , Thomas E. Videbæk , Daichi Hayakawa , W. Benjamin Rogers , Carl P. Goodrich

In many covering settings, it is natural to consider the presence both of elements that we seek to include and of elements that we seek to avoid. This paper introduces a novel combinatorial problem formalizing this tradeoff: from a…

Data Structures and Algorithms · Computer Science 2025-12-01 Sophie Boileau , Andrew Hong , David Liben-Nowell , Alistair Pattison , Anna N. Rafferty , Charlie Roslansky

The (unweighted) point-separation problem asks, given a pair of points $s$ and $t$ in the plane, and a set of candidate geometric objects, for the minimum-size subset of objects whose union blocks all paths from $s$ to $t$. Recent work has…

Computational Geometry · Computer Science 2026-02-16 Jayson Lynch , Jack Spalding-Jamieson

We introduce an efficient and scalable method for density-based multi-material topology optimization, integrating classical mirror descent techniques with point-wise polytopal design constraints. Such constraints arise naturally in this…

Numerical Analysis · Mathematics 2026-05-15 Peter Gangl , Brendan Keith , Dohyun Kim , Boyan S. Lazarov , Thomas M. Surowiec

We propose a general framework for solving inverse self-assembly problems, i.e. designing interactions between elementary units such that they assemble spontaneously into a predetermined structure. Our approach uses patchy particles as…

Soft Condensed Matter · Physics 2022-07-13 John Russo , Flavio Romano , Lukas Kroc , Francesco Sciortino , Lorenzo Rovigatti , Petr Sulc

Designing the topology of three-dimensional structures is a challenging problem due to its memory and time consumption. In this paper, we present a robust and efficient algorithm for solving large-scale 3D topology optimization problems.…

Optimization and Control · Mathematics 2024-03-01 Alfredo Vitorino , Francisco A. M. Gomes

The design space for a self-assembled multicomponent objects ranges from a solution in which every building block is unique to one with the minimum number of distinct building blocks that unambiguously define the target structure. Using a…

Soft Condensed Matter · Physics 2023-03-13 Joakim Bohlin , Andrew J. Turberfield , Ard A. Louis , Petr Šulc

Long-horizon task and motion planning (TAMP) is notoriously difficult to solve, let alone optimally, due to the tight coupling between the interleaved (discrete) task and (continuous) motion planning phases, where each phase on its own is…

Robotics · Computer Science 2024-04-11 Kai Gao , Zihe Ye , Duo Zhang , Baichuan Huang , Jingjin Yu

We show that in the hierarchical tile assembly model, if there is a producible assembly that overlaps a nontrivial translation of itself consistently (i.e., the pattern of tile types in the overlap region is identical in both translations),…

Computational Geometry · Computer Science 2014-11-26 Ho-Lin Chen , David Doty , Ján Maňuch , Arash Rafiey , Ladislav Stacho

If particles interact according to isotropic pair potentials that favor multiple length scales, in principle a large variety of different complex structures can be achieved by self-assembly. We present, motivate, and discuss a conjecture…

Soft Condensed Matter · Physics 2018-11-07 Erdal C. Oğuz , Aleksandar Mijailović , Michael Schmiedeberg

Working in Winfree's abstract tile assembly model, we show that a constant-size tile assembly system can be programmed through relative tile concentrations to build an n x n square with high probability, for any sufficiently large n. This…

Computational Complexity · Computer Science 2015-03-13 David Doty

In this paper, we study the polyhedral structure of an integrated minimum-up/-down time and ramping polytope, which has broad applications in variant industries. The polytope we studied includes minimum-up/-down time, generation…

Optimization and Control · Mathematics 2016-04-11 Kai Pan , Yongpei Guan

We introduce a new model of algorithmic tile self-assembly called size-dependent assembly. In previous models, supertiles are stable when the total strength of the bonds between any two halves exceeds some constant temperature. In this…

Computational Geometry · Computer Science 2015-09-24 Sándor P. Fekete , Robert T. Schweller , Andrew Winslow

Joint object matching, also known as multi-image matching, namely, the problem of finding consistent partial maps among all pairs of objects within a collection, is a crucial task in many areas of computer vision. This problem subsumes…

Optimization and Control · Mathematics 2022-11-29 Antonio De Rosa , Aida Khajavirad

The assembly index of assembly theory quantifies the minimal number of composition steps required to construct an object from elementary components. The study proves that the decision version of the assembly index problem is NP-complete,…

Computational Complexity · Computer Science 2026-04-21 Piotr Masierak

We show how to design a universal shape replicator in a self-assembly system with both attractive and repulsive forces. More precisely, we show that there is a universal set of constant-size objects that, when added to any unknown hole-free…

Computational Geometry · Computer Science 2016-08-02 Cameron Chalk , Erik D. Demaine , Martin L. Demaine , Eric Martinez , Robert Schweller , Luis Vega , Tim Wylie