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Biclustering has gained interest in gene expression data analysis due to its ability to identify groups of samples that exhibit similar behaviour in specific subsets of genes (or vice versa), in contrast to traditional clustering methods…

Applications · Statistics 2024-12-12 Luis A. Vargas-Mieles , Paul D. W. Kirk , Chris Wallace

The Conflict-Driven Cylindrical Algebraic Covering algorithm has proven well suited for performing theory validation checks in the satisfiability modulo theories paradigm for non-linear real arithmetic. CDCAC repurposes the theory…

Data Structures and Algorithms · Computer Science 2026-01-22 Abiola Babatunde , Matthew England , AmirHosein Sadeghimanesh

In consensus clustering, a clustering algorithm is used in combination with a subsampling procedure to detect stable clusters. Previous studies on both simulated and real data suggest that consensus clustering outperforms native algorithms.…

Machine learning methods applied to complex biomedical data has enabled the construction of disease signatures of diagnostic/prognostic value. However, less attention has been given to understanding disease heterogeneity. Semi-supervised…

Quantitative Methods · Quantitative Biology 2020-06-30 Zhijian Yang , Junhao Wen , Christos Davatzikos

Sparse Subspace Clustering (SSC) is a state-of-the-art method for clustering high-dimensional data points lying in a union of low-dimensional subspaces. However, while $\ell_1$ optimization-based SSC algorithms suffer from high…

Machine Learning · Computer Science 2018-02-14 Yanxi Chen , Gen Li , Yuantao Gu

Genome-wide association studies (GWASs) aim to detect genetic risk factors for complex human diseases by identifying disease-associated single-nucleotide polymorphisms (SNPs). The traditional SNP-wise approach along with multiple testing…

Methodology · Statistics 2019-09-25 Yan Xu , Li Xing , Jessica Su , Xuekui Zhang , Weiliang Qiu

Conformal Prediction (CP) is a distribution-free framework for constructing statistically rigorous prediction sets. While popular variants such as CD-split improve CP's efficiency, they often yield prediction sets composed of multiple…

Machine Learning · Statistics 2025-09-29 Mingyi Zheng , Hongyu Jiang , Yizhou Lu , Jiaye Teng

Subspace clustering discovers the clusters embedded in multiple, overlapping subspaces of high dimensional data. Many significant subspace clustering algorithms exist, each having different characteristics caused by the use of different…

Databases · Computer Science 2013-04-15 Sunita Jahirabadkar , Parag Kulkarni

Lennard-Jones clusters, while an easy system, have a significant number of non equivalent configurations that increases rapidly with the number of atoms in the cluster. Here, we aim at determining the cluster partition function; we use the…

Computational Physics · Physics 2026-02-20 Lune Maillard , Fabio Finocchi , César Godinho , Martino Trassinelli

The clustering algorithm plays a crucial role in speaker diarization systems. However, traditional clustering algorithms suffer from the complex distribution of speaker embeddings and lack of digging potential relationships between speakers…

Audio and Speech Processing · Electrical Eng. & Systems 2023-06-27 Jie Wang , Zhicong Chen , Haodong Zhou , Lin Li , Qingyang Hong

Gene annotation has traditionally required direct comparison of DNA sequences between an unknown gene and a database of known ones using string comparison methods. However, these methods do not provide useful information when a gene does…

Machine Learning · Computer Science 2019-09-17 James K. Senter , Taylor M. Royalty , Andrew D. Steen , Amir Sadovnik

Semi-supervised semantic segmentation relieves the reliance on large-scale labeled data by leveraging unlabeled data. Recent semi-supervised semantic segmentation approaches mainly resort to pseudo-labeling methods to exploit unlabeled…

Computer Vision and Pattern Recognition · Computer Science 2024-04-11 Hui Xiao , Yuting Hong , Li Dong , Diqun Yan , Jiayan Zhuang , Junjie Xiong , Dongtai Liang , Chengbin Peng

Many computerized methods for RNA-RNA interaction structure prediction have been developed. Recently, $O(N^6)$ time and $O(N^4)$ space dynamic programming algorithms have become available that compute the partition function of RNA-RNA…

Mathematical Physics · Physics 2010-07-15 Andrew X. Li , Manja Marz , Jing Qin , Christian M. Reidys

Sequence alignment is a cornerstone technique in computational biology for assessing similarities and differences among biological sequences. A key variant, sequence-to-graph alignment, plays a crucial role in effectively capturing genetic…

Computational Complexity · Computer Science 2026-02-16 Xingfu Li

Kernel segmentation aims at partitioning a data sequence into several non-overlapping segments that may have nonlinear and complex structures. In general, it is formulated as a discrete optimization problem with combinatorial constraints. A…

Machine Learning · Computer Science 2022-06-23 Tung Doan , Atsuhiro Takasu

This paper studies sequencing and mapping methods that rely solely on pooling and shotgun sequencing of clones. First, we scrutinize and improve the recently proposed Clone-Array Pooled Shotgun Sequencing (CAPSS) method, which delivers a…

Genomics · Quantitative Biology 2007-05-23 Miklós Csürös , Bingshan Li , Aleksandar Milosavljevic

Various alignment problems arising in cryo-electron microscopy, community detection, time synchronization, computer vision, and other fields fall into a common framework of synchronization problems over compact groups such as Z/L, U(1), or…

Information Theory · Computer Science 2018-09-14 Amelia Perry , Alexander S. Wein , Afonso S. Bandeira , Ankur Moitra

The impracticality of posterior sampling has prevented the widespread adoption of spike-and-slab priors in high-dimensional applications. To alleviate the computational burden, optimization strategies have been proposed that quickly find…

Methodology · Statistics 2021-03-30 Lizhen Nie , Veronika Ročková

Several methods for triclustering three-dimensional data require the cluster size or the number of clusters in each dimension to be specified. To address this issue, the Multi-Slice Clustering (MSC) for 3-order tensor finds signal slices…

Machine Learning · Computer Science 2023-03-27 Dina Faneva Andriantsiory , Joseph Ben Geloun , Mustapha Lebbah

Image clustering is an important and open-challenging task in computer vision. Although many methods have been proposed to solve the image clustering task, they only explore images and uncover clusters according to the image features, thus…

Computer Vision and Pattern Recognition · Computer Science 2023-04-11 Shaotian Cai , Liping Qiu , Xiaojun Chen , Qin Zhang , Longteng Chen