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Structural changes in retinal blood vessels are critical biomarkers for the onset and progression of glaucoma and other ocular diseases. However, current vessel segmentation approaches largely rely on supervised learning and extensive…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Cheng Huang , Weizheng Xie , Fan Gao , Yutong Liu , Ruoling Wu , Zeyu Han , Jingxi Qiu , Xiangxiang Wang , Zhenglin Yang , Hao Wang , Yongbin Yu

Vascular structures in the retina contain important information for the detection and analysis of ocular diseases, including age-related macular degeneration, diabetic retinopathy and glaucoma. Commonly used modalities in diagnosis of these…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Erick O. Rodrigues , Aura Conci , Panos Liatsis

The transformer models have shown promising effectiveness in dealing with various vision tasks. However, compared with training Convolutional Neural Network (CNN) models, training Vision Transformer (ViT) models is more difficult and relies…

Computer Vision and Pattern Recognition · Computer Science 2022-07-28 Jiawang Bai , Li Yuan , Shu-Tao Xia , Shuicheng Yan , Zhifeng Li , Wei Liu

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Precision in identifying and differentiating micro and macro blood vessels in the retina is crucial for the diagnosis of retinal diseases, although it poses a significant challenge. Current autoencoding-based segmentation approaches…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Rui Yang , Shunpu Zhang

Analyzing the morphological attributes of blood vessels plays a critical role in the computer-aided diagnosis of many cardiovascular and ophthalmologic diseases. Although being extensively studied, segmentation of blood vessels,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-12 Yicheng Wu , Chengwei Pan , Shuqi Wang , Ming Zhang , Yong Xia , Yizhou Yu

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

Human-Computer Interaction · Computer Science 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Segmentation of retinal vessel images is critical to the diagnosis of retinopathy. Recently, convolutional neural networks have shown significant ability to extract the blood vessel structure. However, it remains challenging to refined…

Image and Video Processing · Electrical Eng. & Systems 2022-02-22 Geng-Xin Xu , Chuan-Xian Ren

Macular Holes, Central serous retinopathy and Diabetic Retinopathy are one of the most widespread maladies of the eyes responsible for either partial or complete vision loss, thus making it clear that early detection of the mentioned…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Shashwat Jha , Vishvaditya Luhach , Raju Poddar

Retinal blood vessel segmentation can extract clinically relevant information from fundus images. As manual tracing is cumbersome, algorithms based on Convolution Neural Networks have been developed. Such studies have used small publicly…

Image and Video Processing · Electrical Eng. & Systems 2024-06-24 Jeremiah Fadugba , Patrick Köhler , Lisa Koch , Petru Manescu , Philipp Berens

Methods for automated retinal vessel segmentation play an important role in the treatment and diagnosis of many eye and systemic diseases. With the fast development of deep learning methods, more and more retinal vessel segmentation methods…

Image and Video Processing · Electrical Eng. & Systems 2023-06-13 Gorana Gojić , Ognjen Kundačina , Dragiša Mišković , Dinu Dragan

Biomedical image classification requires capturing of bio-informatics based on specific feature distribution. In most of such applications, there are mainly challenges due to limited availability of samples for diseased cases and imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2025-10-23 Arun K. Sharma , Nishchal K. Verma

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yan Hu , Zhongxi Qiu , Dan Zeng , Li Jiang , Chen Lin , Jiang Liu

The precise detection of blood vessels in retinal images is crucial to the early diagnosis of the retinal vascular diseases, e.g., diabetic, hypertensive and solar retinopathies. Existing works often fail in predicting the abnormal areas,…

Image and Video Processing · Electrical Eng. & Systems 2021-09-23 Jun Wang , Yang Zhao , Linglong Qian , Xiaohan Yu , Yongsheng Gao

We introduce a new technique for generating retinal fundus images that have anatomically accurate vascular structures, using diffusion models. We generate artery/vein masks to create the vascular structure, which we then condition to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Sojung Go , Younghoon Ji , Sang Jun Park , Soochahn Lee

Disease complications can alter vascular network morphology and disrupt tissue functioning. Diabetic retinopathy, for example, is a complication of types 1 and 2 diabetes mellitus that can cause blindness. Microvascular diseases are…

Quantitative Methods · Quantitative Biology 2022-09-13 John T. Nardini , Charles W. J. Pugh , Helen M. Byrne

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

Automatic analysis of retinal blood images is of vital importance in diagnosis tasks of retinopathy. Segmenting vessels accurately is a fundamental step in analysing retinal images. However, it is usually difficult due to various imaging…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Yishuo Zhang , Albert C. S. Chung

Vessel segmentation of retinal images is a key diagnostic capability in ophthalmology. This problem faces several challenges including low contrast, variable vessel size and thickness, and presence of interfering pathology such as…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Venkateswararao Cherukuri , Vijay Kumar BG , Raja Bala , Vishal Monga

The detection of retinal vessel is of great importance in the diagnosis and treatment of many ocular diseases. Many methods have been proposed for vessel detection. However, most of the algorithms neglect the connectivity of the vessels,…

Image and Video Processing · Electrical Eng. & Systems 2019-10-29 Lei Mou , Li Chen , Jun Cheng , Zaiwang Gu , Yitian Zhao , Jiang Liu