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Confocal microscopy is the standard approach for obtaining volumetric images of a sample with high axial and lateral resolution, especially when dealing with scattering samples. Unfortunately, a confocal microscope is quite expensive…

Confocal and multi-photon microscopy are widely used for in-vivo fluorescence imaging of biological tissues such as the brain, offering non-invasive access up to ~1 mm depth without major loss in performance. A recently-developed…

Image decomposition plays a crucial role in various computer vision tasks, enabling the analysis and manipulation of visual content at a fundamental level. Overlapping images, which occur when multiple objects or scenes partially occlude…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Saúl Alonso-Monsalve , Davide Sgalaberna , Xingyu Zhao , Adrien Molines , Clark McGrew , André Rubbia

Segmentation of objects in microscopy images is required for many biomedical applications. We introduce object-centric embeddings (OCEs), which embed image patches such that the spatial offsets between patches cropped from the same object…

Machine Learning · Computer Science 2023-10-13 Steffen Wolf , Manan Lalit , Henry Westmacott , Katie McDole , Jan Funke

The main advantage of two-photon fluorescence confocal microscopy is the low absorption obtained with live tissues at the wavelengths of operation. However, the resolution of two-photon fluorescence confocal microscopes is lower than in the…

Biological Physics · Physics 2009-11-13 N. Sandeau , H. Giovannini

Accurately estimating the pose of an object is a crucial task in computer vision and robotics. There are two main deep learning approaches for this: geometric representation regression and iterative refinement. However, these methods have…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Jaewoo Park , Jaeguk Kim , Nam Ik Cho

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Avelino Javer , Jens Rittscher

Light sheet fluorescence microscopy provides optical sectioning and is widely used in volumetric imaging of large specimens. However, the axial resolution and the lateral Field of View (FoV) of the system, defined by the light sheet,…

Optics · Physics 2021-06-16 Hongjin Li , Zihan Wu , Zhichao Yang , Karl Zhanghao , Peng Xi , Dayong Jin

Fourier optics, the principle of using Fourier Transformation to understand the functionalities of optical elements, lies at the heart of modern optics, and has been widely applied to optical information processing, imaging, holography etc.…

Image denoising is a typical ill-posed problem due to complex degradation. Leading methods based on normalizing flows have tried to solve this problem with an invertible transformation instead of a deterministic mapping. However, the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-01 Wenchao Du , Hu Chen , Yi Zhang , H. Yang

At optical frequencies, interactions of the electric field component of light with matter are dominating, whereas magnetic dipole transitions are inherently weak and challenging to access independently from electric dipole transitions.…

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

Computer Vision and Pattern Recognition · Computer Science 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Microparticles ranging from sub-microns to millimeter in size are a common form of matter in magnetic fusion environment, and they are highly mobile due to their small mass. Different forces in addition to gravity can affect their motion…

Instrumentation and Detectors · Physics 2018-08-01 Pinghan Chu , Bradley T. Wolfe , Zhehui Wang

Traditional methods for biological shape inference, such as deep learning (DL) and active contour models, face important limitations in 3D. DL approaches require large annotated datasets, which are often impractical to obtain, while active…

Biological Physics · Physics 2025-08-04 Sacha Ichbiah , Anshuman Sinha , Fabrice Delbary , Hervé Turlier

We predict the existence of a novel class of multidimensional light localizations in out-of-equilibrium ferroelectric crystals. In two dimensions, the non-diffracting beams form at arbitrary low power level and propagate even when their…

Optics · Physics 2013-05-29 Claudio Conti , Aharon J. Agranat , Eugenio DelRe

Doping of silicon via phosphene exposures alternating with molecular beam epitaxy overgrowth is a path to Si:P substrates for conventional microelectronics and quantum information technologies. The technique also provides a new and…

Many important microscopy samples, such as liquid crystals, biological tissue, or starches, are birefringent in nature. They scatter light differently depending on the light polarization and molecular orientations. The complete…

Optics · Physics 2022-12-26 Herve Hugonnet , Moosung Lee , Seungwoo Shin , YongKeun Park

Three dimensional Polarized Light Imaging (3D-PLI) is an optical technique which allows mapping the spatial fiber architecture of fibrous postmortem tissues, at sub-millimeter resolutions. Here, we propose an analytical and fast approach to…

Medical Physics · Physics 2020-12-18 A. Alimi , S. Deslauriers-Gauthier , F. Matuschke , A. Müller , S. E. A. Muenzing , M. Axer , R. Deriche

One common task in image forensics is to detect spliced images, where multiple source images are composed to one output image. Most of the currently best performing splicing detectors leverage high-frequency artifacts. However, after an…

Computer Vision and Pattern Recognition · Computer Science 2022-06-23 Benjamin Hadwiger , Christian Riess

This paper is about 3D pose estimation on LiDAR scans with extremely minimal storage requirements to enable scalable mapping and localisation. We achieve this by clustering all points of segmented scans into semantic objects and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-08 Georgi Pramatarov , Matthew Gadd , Paul Newman , Daniele De Martini