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This paper presents a micro-mechanical approach to describe the effects of thermo-oxidation on the constitutive behavior of aged elastomers at the long-range timescales. In particular, this model focuses on the effects of thermo-oxidative…

Soft Condensed Matter · Physics 2018-11-01 Hamid Mohammadi , Roozbeh Dargazany

We propose a physics and chemistry-based constitutive framework to predict the stress responses of thermo-chemically aged elastomers and capture their brittle failure using the phase-field approach. High-temperature aging in the presence of…

Materials Science · Physics 2024-01-25 Aimane Najmeddine , Maryam Shakiba

Aging remains a fundamental open problem in modern biology. Although there exist a number of theories on aging on the cellular scale, nearly nothing is known about how microscopic failures cascade to macroscopic failures of tissues, organs…

Tissues and Organs · Quantitative Biology 2017-07-10 Aylin Acun , Dervis Can Vural , Pinar Zorlutuna

This paper presents a physics-based constitutive equation to predict the thermo-chemical aging in elastomers. High-temperature oxidation in elastomers is a complex phenomenon. The macromolecular network of elastomers' microstructures…

Materials Science · Physics 2021-04-20 Maryam Shakiba , Aimane Najmeddine

This paper proposes a physio-chemically-based constitutive framework to simulate and predict the response of semi-crystalline low-density polyethylene (LDPE) to severe photo-oxidation. Photo-oxidation induced by exposure to Ultra-Violet…

Materials Science · Physics 2022-01-28 Aimane Najmeddine , Zhen Xu , Guoliang Liu , Alan R. Esker , Maryam Shakiba

Biological soft tissues exhibit substantial inter-subject variability, making the automation of constitutive material modeling essential for patient-specific analysis and design. Such materials are not only highly nonlinear but also display…

Computational Physics · Physics 2026-04-16 Bahador Bahmani

Aging is considered as the property of the elements of a system to be less prone to change states as they get older. We incorporate aging into the noisy voter model, a stochastic model in which the agents modify their binary state by means…

Statistical Mechanics · Physics 2018-09-06 Oriol Artime , Antonio F. Peralta , Raúl Toral , José J. Ramasco , Maxi San Miguel

This paper proposes a proof of concept application of a biphasic constitutive model to identify the mechanical properties of in vivo human skin under extension. Although poromechanics theory has been extensively used to model other soft…

The understanding of morphogenesis in living organisms has been renewed by tremendous progressin experimental techniques that provide access to cell-scale, quantitative information both on theshapes of cells within tissues and on the genes…

Biological Physics · Physics 2015-09-30 Sham Tlili , Cyprien Gay , Francois Graner , Philippe Marcq , François Molino , Pierre Saramito

Purpose: From the myofibrils to the whole muscle scale, muscle micro-constituents exhibit passive and active mechanical properties, potentially coupled to electrical, chemical, and thermal properties. Experimental characterization of some…

Medical Physics · Physics 2024-06-25 Aude Loumeaud , Philippe Pouletaut , Sabine Bensamoun , Daniel George , Simon Chatelin

Process-structure-property relationships are fundamental in materials science and engineering and are key to the development of new and improved materials. Symbolic regression serves as a powerful tool for uncovering mathematical models…

Materials Science · Physics 2025-11-12 Evgeniya Kabliman , Gabriel Kronberger

The mortality rate of many complex multicellular organisms increase with age, which suggests that net aging damage is accumulative, despite remodeling processes. But how exactly do little mishaps in the cellular level accumulate and spread…

Tissues and Organs · Quantitative Biology 2017-12-12 Daniel Suma , Aylin Acun , Pinar Zorlutuna , Dervis Can Vural

Machine learning approaches informed by physics have offered new insights into the discovery of constitutive models from data, helping overcome some limitations of traditional constitutive modelling while reducing the cost of otherwise…

Materials Science · Physics 2026-05-19 Filippo Masi

Collagen fibrils are the most important structural component of tendons. Their crimped structure and parallel arrangement within the tendon lead to a distinctive non-linear stress-strain curve when a tendon is stretched. Microstructural…

Tissues and Organs · Quantitative Biology 2021-03-09 James Gregory , Tom Shearer , Andrew L. Hazel

Classically, the mechanical response of materials is described through constitutive models, often in the form of constrained ordinary differential equations. These models have a very limited number of parameters, yet, they are extremely…

Machine Learning · Computer Science 2022-09-27 Ehsan Haghighat , Sahar Abouali , Reza Vaziri

Constitutive modeling lies at the core of mechanics, allowing us to map strains onto stresses for a material in a given mechanical setting. Historically, researchers relied on phenomenological modeling where simple mathematical…

Computational Engineering, Finance, and Science · Computer Science 2024-08-28 Asghar A. Jadoon , Knut A. Meyer , Jan N. Fuhg

We describe a percolation-type approach to modeling of the processes of aging and certain other properties of tissues analyzed as systems consisting of interacting cells. Tissues are considered as structures made of regular healthy,…

Statistical Mechanics · Physics 2016-01-28 Vladimir Privman , Vyacheslav Gorshkov , Sergiy Libert

Purpose: The purpose of this work is to apply a recently proposed constitutive model for mechanically induced martensitic transformations to the prediction of transformation loci. Additionally, this study aims to elucidate if a…

Viscoplastic flow of polycrystalline metallic materials is the result of motion and interaction of dislocations, line defects of the crystalline structure. In the microstructural (physics-based) constitutive model presented in this paper,…

Materials Science · Physics 2018-09-11 S. Amir H. Motaman , Ulrich Prahl

Collagenolytic degradation is a process fundamental to tissue remodeling. The microarchitecture of collagen fibril networks changes during development, aging, and disease. Such changes to microarchitecture are often accompanied by changes…

Biological Physics · Physics 2024-08-13 B. Debnath , B. N. Narasimhan , S. I. Fraley , P. Rangamani
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