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Despite the tremendous success in computer vision, deep convolutional networks suffer from serious computation costs and redundancies. Although previous works address this issue by enhancing diversities of filters, they have not considered…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Yang Hu , Guihua Wen , Mingnan Luo , Dan Dai , Wenming Cao , Zhiwen Yu , Wendy Hall

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Shaojie Li , Zhaoshuo Diao

Flow-Imaging Microscopy (FIM) is commonly used in both academia and industry to characterize subvisible particles (those $\le 25 \mu m$ in size) in protein therapeutics. Pharmaceutical companies are required to record vast volumes of FIM…

Quantitative Methods · Quantitative Biology 2017-09-04 Christopher P. Calderon , Austin L. Daniels , Theodore W. Randolph

Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use…

Image and Video Processing · Electrical Eng. & Systems 2026-05-14 Md Fahimul Kabir Chowdhury , Jannatul Ferdous

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega

Confocal and multi-photon microscopy are widely used for in-vivo fluorescence imaging of biological tissues such as the brain, offering non-invasive access up to ~1 mm depth without major loss in performance. A recently-developed…

Semantic image segmentation is one of the most important tasks in medical image analysis. Most state-of-the-art deep learning methods require a large number of accurately annotated examples for model training. However, accurate annotation…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Ning Zhang , Susan Francis , Rayaz Malik , Xin Chen

This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Takayasu Moriya , Holger R. Roth , Shota Nakamura , Hirohisa Oda , Kai Nagara , Masahiro Oda , Kensaku Mori

The opaque nature of deep learning models remains a significant barrier to their clinical adoption in medical imaging. This paper presents a multimodal explainability framework that bridges the gap between convolutional neural network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Paul Valery Nguezet , Elie Tagne Fute , Yusuf Brima , Benoit Martin Azanguezet , Marcellin Atemkeng

Optical transmission spectroscopy is one method to understand brain tissue structural properties from brain tissue biopsy samples, yet manual interpretation is resource intensive and prone to inter observer variability. Deep convolutional…

Medical Physics · Physics 2025-05-20 Mohnish Sao , Mousa Alrubayan , Prabhakar Pradhan

Early detection and accurate diagnosis are essential to improving patient outcomes. The use of convolutional neural networks (CNNs) for tumor detection has shown promise, but existing models often suffer from overparameterization, which…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Muhammad Irfan , Anum Nawaz , Riku Klen , Abdulhamit Subasi , Tomi Westerlund , Wei Chen

High-resolution real-time intraocular imaging of retina at the cellular level is very challenging due to the vulnerable and confined space within the eyeball as well as the limited availability of appropriate modalities. A probe-based…

Deep neural networks have been applied to improve the image quality of fluorescence microscopy imaging. Previous methods are based on convolutional neural networks (CNNs) which generally require more time-consuming training of separate…

Cluster of microcalcifications can be an early sign of breast cancer. In this paper we propose a novel approach based on convolutional neural networks for the detection and segmentation of microcalcification clusters. In this work we used…

Computer Vision and Pattern Recognition · Computer Science 2018-09-12 Gabriele Valvano , Gianmarco Santini , Nicola Martini , Andrea Ripoli , Chiara Iacconi , Dante Chiappino , Daniele Della Latta

Medical image segmentation is a relevant problem, with deep learning being an exponent. However, the necessity of a high volume of fully annotated images for training massive models can be a problem, especially for applications whose images…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Matheus A. Cerqueira , Flávia Sprenger , Bernardo C. A. Teixeira , Alexandre X. Falcão

We present a fast and accurate analytical method for fluorescence lifetime imaging microscopy (FLIM) using the extreme learning machine (ELM). We used extensive metrics to evaluate ELM and existing algorithms. First, we compared these…

Biological Physics · Physics 2022-03-28 Zhenya Zang , Dong Xiao , Quan Wang , Zinuo Li , Wujun Xie , Yu Chen , David Day Uei Li

The automated detection of cancerous tumors has attracted interest mainly during the last decade, due to the necessity of early and efficient diagnosis that will lead to the most effective possible treatment of the impending risk. Several…

Image and Video Processing · Electrical Eng. & Systems 2023-10-13 Vasileios E. Papageorgiou , Pantelis Dogoulis , Dimitrios-Panagiotis Papageorgiou

Traditional diagnostic methods like colonoscopy are invasive yet critical tools necessary for accurately diagnosing colorectal cancer (CRC). Detection of CRC at early stages is crucial for increasing patient survival rates. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Xinliu Zhong , Leo Hwa Liang , Angela S. Koh , Yeo Si Yong

Identifying and characterizing the patient's blood samples is indispensable in diagnostics of malignance suspicious. A painstaking and sometimes subjective task is used in laboratories to manually classify white blood cells. Neural…

Image and Video Processing · Electrical Eng. & Systems 2020-10-23 Daouda Diouf , Djibril Seck , Mountaga Diop , Abdoulye Ba

Contrastive learning (CL) has become a powerful approach for learning representations from unlabeled images. However, existing CL methods focus predominantly on visual appearance features while neglecting topological characteristics (e.g.,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Guangyu Meng , Pengfei Gu , Peixian Liang , John P. Lalor , Erin Wolf Chambers , Danny Z. Chen