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Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…
In recent years, the use of deep learning (DL) methods, including convolutional neural networks (CNNs) and vision transformers (ViTs), has significantly advanced computational pathology, enhancing both diagnostic accuracy and efficiency.…
Mycosis fungoides (MF) is a rare, potentially life threatening skin disease, which in early stages clinically and histologically strongly resembles Eczema, a very common and benign skin condition. In order to increase the survival rate, one…
Whole slide imaging (WSI) is an emerging technology for digital pathology. The process of autofocusing is the main influence of the performance of WSI. Traditional autofocusing methods either are time-consuming due to repetitive mechanical…
Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…
Angiogenesis, the development of new vasculature, is a critical process in the growth of new tumors. Driven by a goal to understand this aspect of cancer proliferation, I develop a discrete computationally optimized mathematical model of…
Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…
Whole slide images are the foundation of digital pathology for the diagnosis and treatment of carcinomas. Writing pathology reports is laborious and error-prone for inexperienced pathologists. To reduce the workload and improve clinical…
The ability to predict the attention of expert pathologists could lead to decision support systems for better pathology training. We developed methods to predict the spatio-temporal (where and when) movements of pathologists' attention as…
Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…
We present a novel diffusion-based approach to generate synthetic histopathological Whole Slide Images (WSIs) at an unprecedented gigapixel scale. Synthetic WSIs have many potential applications: They can augment training datasets to…
How similar are two images? In computational pathology, where Whole Slide Images (WSIs) of digitally scanned tissue samples from patients can be multi-gigapixels in size, determination of degree of similarity between two WSIs is a…
Whole slide imaging (WSI) has transformed digital pathology by enabling computational analysis of gigapixel histopathology images. Recent foundation model advances have accelerated progress in computational pathology, facilitating joint…
Accurate analysis of histopathological images is critical for disease diagnosis and treatment planning. Whole-slide images (WSIs), which digitize tissue specimens at gigapixel resolution, are fundamental to this process but require…
Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…
Histopathological cancer diagnostics has become more complex, and the increasing number of biopsies is a challenge for most pathology laboratories. Thus, development of automatic methods for evaluation of histopathological cancer sections…
Computational pathology involves the digitization of stained tissues into whole-slide images (WSIs) that contain billions of pixels arranged as contiguous patches. Statistical analysis of WSIs largely focuses on classification via multiple…
This study presents a convolutional neural network (CNN)-based approach for the multi-class classification of brain tumors using magnetic resonance imaging (MRI) scans. We utilize a publicly available dataset containing MRI images…
Angiogenesis, the formation of new vessels, is one of the key mechanisms in tumor development and an appealing target for therapy. Non-invasive, high-resolution, high sensitivity, quantitative 3D imaging techniques are required to correctly…
Cervical Cancer continues to be the leading gynecological malignancy, posing a persistent threat to women's health on a global scale. Early screening via cytology Whole Slide Image (WSI) diagnosis is critical to prevent this Cancer…