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The Graovac-Pisanski index, also called the modified Wiener index, was introduced in 1991 and represents an extension of the original Wiener index, because it considers beside the distances in a graph also its symmetries. Similarly as…

Combinatorics · Mathematics 2021-10-13 Matevž Črepnjak , Martin Knor , Niko Tratnik , Petra Žigert Pleteršek

The Graovac-Pisanski index, which is also called the modified Wiener index, was introduced in 1991 by A. Graovac and T. Pisanski. This variation of the classical Wiener index takes into account the symmetries of a graph. In 2016 M. Ghorbani…

Combinatorics · Mathematics 2018-08-28 Niko Tratnik

The Wiener polarity index $W_p$, one of the most studied molecular structure descriptors, was devised by the chemist Harold Wiener for predicting the boiling points of alkanes. The index $W_p$ for chemical trees (chemical graphs…

Combinatorics · Mathematics 2021-02-03 Sadia Noureen , Akhlaq Ahmad Bhatti , Akbar Ali

The Wiener index is one of the oldest graph parameter which is used to study molecular-graph-based structure. This parameter was first proposed by Harold Wiener in 1947 to determining the boiling point of paraffin. The Wiener index of a…

Discrete Mathematics · Computer Science 2014-09-09 Kalyani Das

Let $G=(V(G),E(G))$ be a molecular graph, where $V(G)$ and $E(G)$ are the sets of vertices (atoms) and edges (bonds). A topological index of a molecular graph is a numerical quantity which helps to predict the chemical/physical properties…

Combinatorics · Mathematics 2022-04-25 Bo Bi , Muhammad Kamran Jamil , Khawaja Muhammad Fahd , Tian-Le Sun , Imran Ahmad , Lei Ding

In this paper, we consider a molecular descriptor called the Wiener polarity index, which is defined as the number of unordered pairs of vertices at distance three in a graph. Molecular descriptors play a fundamental role in chemistry,…

Combinatorics · Mathematics 2019-04-09 Niko Tratnik

Topological indices have important role in theoretical chemistry for QSPR researches. Among the all topological indices the Randi\'c and the Zagreb indices have been used more considerably than any other topological indices in chemical and…

Combinatorics · Mathematics 2017-01-12 Süleyman Ediz

In this note, we discuss the method explained in the recent paper [P. Manuel, I. Rajasingh, B. Rajan, R. Sundara Rajan, A New Approach To Compute Wiener Index, Journal of Computational and Theoretical Nanoscience 10, (2013) 1515-1521.] for…

Combinatorics · Mathematics 2013-07-25 Aleksandar Ilic

Establishing quantitative correlations between various molecular properties and chemical structures is of great technological importance for environmental and medical aspects. These approaches are referred to as Quantitative…

Materials Science · Physics 2024-04-16 H. M. Nagesh

Molecular property prediction is of crucial importance in many disciplines such as drug discovery, molecular biology, or material and process design. The frequently employed quantitative structure-property/activity relationships…

Biomolecules · Quantitative Biology 2024-01-17 Jan G. Rittig , Qinghe Gao , Manuel Dahmen , Alexander Mitsos , Artur M. Schweidtmann

Topological indices are graph invariants numeric quantities, which are utilized by researchers to analyze a variety of physiochemical aspects of molecules. The goal of developing topological indices is to give each chemical structure a…

Combinatorics · Mathematics 2022-12-09 Sohan Lal , Karnika Sharma , Vijay Kumar Bhat

Analysis of chemical graphs is becoming a major research topic in computational molecular biology due to its potential applications to drug design. One of the major approaches in such a study is inverse quantitative structure…

Computational Engineering, Finance, and Science · Computer Science 2020-12-04 Tatsuya Akutsu , Hiroshi Nagamochi

Ionic liquids (ILs) are an emerging group of chemical compounds which possess promising properties such as having negligible vapor pressure. These so called designer solvents have the potential to replace volatile organic compounds in…

Chemical Physics · Physics 2016-12-06 A. Mehrkesh , A. T. Karunanithi

The paper discusses the edge hyper-Zagreb index of a graph, which is calculated by replacing vertex degrees with edge degrees. The degree of an edge is determined by adding up the degrees of the end vertices of the edge and subtracting 2.…

General Mathematics · Mathematics 2024-06-26 Z. Aliannejadi , S. Shafiee Alamoti

This study conducts a Quantitative Structure Property Relationship (QSPR) analysis to explore the correlation between the physical properties of drug molecules and their topological indices using machine learning techniques. While prior…

Biomolecules · Quantitative Biology 2025-05-14 M. J. Nadjafi Arani , S. Sorgun , M. Mirzargar

Mapper, a topological algorithm, is frequently used as an exploratory tool to build a graphical representation of data. This representation can help to gain a better understanding of the intrinsic shape of high-dimensional genomic data and…

Genomics · Quantitative Biology 2023-07-19 Erik J. Amézquita , Farzana Nasrin , Kathleen M. Storey , Masato Yoshizawa

Data-driven prediction of molecular properties presents unique challenges to the design of machine learning methods concerning data structure/dimensionality, symmetry adaption, and confidence management. In this paper, we present a…

Machine Learning · Computer Science 2019-01-31 Yu-Hang Tang , Wibe A. de Jong

The geometric--arithmetic indices are widely considered in the chemical graph theory in the last decade. The reason of introducing new indices is to gain prediction of target properties of considered molecules that is better than the…

Chemical Physics · Physics 2019-06-03 Matevž Črepnjak , Petra Žigert Pleteršek

Analysis of chemical graphs is a major research topic in computational molecular biology due to its potential applications to drug design. One approach is inverse quantitative structure activity/property relationship (inverse QSAR/QSPR)…

Data Structures and Algorithms · Computer Science 2020-09-22 Naveed Ahmed Azam , Jianshen Zhu , Yanming Sun , Yu Shi , Aleksandar Shurbevski , Liang Zhao , Hiroshi Nagamochi , Tatsuya Akutsu

The Wiener index of a connected graph is the sum of the distance of all pairs of distinct vertices. It was introduced by Wiener in 1947 to analyze some aspects of branching by fitting experimental data for several properties of alkane…

Combinatorics · Mathematics 2020-01-10 Peter Luo , Cun-Quan Zhang , Xiao-Dong Zhang
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