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The CoHSI (Conservation of Hartley-Shannon Information) distribution is at the heart of a wide-class of discrete systems, defining the length distribution of their components amongst other global properties. Discrete systems such as the…

Other Quantitative Biology · Quantitative Biology 2018-06-26 Les Hatton , Gregory Warr

The CoHSI (Conservation of Hartley-Shannon Information) distribution is at the heart of a wide-class of discrete systems, defining (amongst other properties) the length distribution of their components. Discrete systems such as the known…

Other Quantitative Biology · Quantitative Biology 2018-07-31 Les Hatton , Gregory Warr

A mechanism-free and symbol-agnostic conservation principle, the Conservation of Hartley-Shannon Information (CoHSI) is predicted to constrain the structure of discrete systems regardless of their origin or function. Despite their distinct…

Other Quantitative Biology · Quantitative Biology 2019-02-26 Les Hatton , Gregory Warr

The length distribution of proteins measured in amino acids follows the CoHSI (Conservation of Hartley-Shannon Information) probability distribution. In previous papers we have verified various predictions of this using the Uniprot database…

Other Quantitative Biology · Quantitative Biology 2018-10-23 Les Hatton , Gregory Warr

The Conservation of Energy plays a pivotal part in the development of the physical sciences. With the growth of computation and the study of other discrete token based systems such as the genome, it is useful to ask if there are…

Information Theory · Computer Science 2012-09-25 Les Hatton

In a matching paper (arXiv:1207.5027), I proved that Conservation of Size and Information in a discrete token based system is overwhelmingly likely to lead to a power-law component size distribution with respect to the size of its unique…

Information Theory · Computer Science 2012-09-11 Les Hatton

Intracellular protein patterns are described by (nearly) mass-conserving reaction-diffusion systems. While these patterns initially form out of a homogeneous steady state due to the well-understood Turing instability, no general theory…

Pattern Formation and Solitons · Physics 2024-01-11 Henrik Weyer , Fridtjof Brauns , Erwin Frey

Proteins inherently possess a consistent sequence-structure duality. The abundance of protein sequence data, which can be readily represented as discrete tokens, has driven fruitful developments in protein language models (pLMs). A key…

Computational Engineering, Finance, and Science · Computer Science 2026-05-29 Yi Zhou , Haohao Qu , Yunqing Liu , Shanru Lin , Le Song , Wenqi Fan

Zipf's law is a paradigm describing the importance of different elements in communication systems, especially in linguistics. Despite the complexity of the hierarchical structure of language, music has in some sense an even more complex…

Physics and Society · Physics 2023-11-20 Marc Serra-Peralta , Joan Serrà , Álvaro Corral

In previous papers we have described with strong experimental support, the organising role that CoHSI (Conservation of Hartley-Shannon Information) plays in determining important global properties of all known proteins, from defining the…

Other Quantitative Biology · Quantitative Biology 2018-11-07 Les Hatton , Gregory Warr

Many complex systems are modular. Such systems can be represented as "component systems", i.e., sets of elementary components, such as LEGO bricks in LEGO sets. The bricks found in a LEGO set reflect a target architecture, which can be…

Genomics · Quantitative Biology 2018-04-24 Andrea Mazzolini , Marco Gherardi , Michele Caselle , Marco Cosentino Lagomarsino , Matteo Osella

Human language has a distinct systematic structure, where utterances break into individually meaningful words which are combined to form phrases. We show that natural-language-like systematicity arises in codes that are constrained by a…

Computation and Language · Computer Science 2025-11-19 Richard Futrell , Michael Hahn

In multicenter biomedical research, integrating data from multiple decentralized sites provides more robust and generalizable findings due to its larger sample size and the ability to account for the between-site heterogeneity. However,…

Methodology · Statistics 2025-12-29 Xiaokang Liu , Yuchen Yang , Yifei Sun , Jiang Bian , Yanyuan Ma , Raymond J. Carroll , Yong Chen

Zipf's law is a hallmark of several complex systems with a modular structure, such as books composed by words or genomes composed by genes. In these component systems, Zipf's law describes the empirical power law distribution of component…

Statistical Mechanics · Physics 2018-12-05 Andrea Mazzolini , Alberto Colliva , Michele Caselle , Matteo Osella

In many complex applications, data heterogeneity and homogeneity exist simultaneously. Ignoring either one will result in incorrect statistical inference. In addition, coping with complex data that are non-Euclidean becomes more common. To…

Methodology · Statistics 2021-05-28 Zixuan Han , Tao Li , Jinhong You

Most real systems consist of a large number of interacting, multi-typed components, while most contemporary researches model them as homogeneous networks, without distinguishing different types of objects and links in the networks.…

Social and Information Networks · Computer Science 2015-11-17 Chuan Shi , Yitong Li , Jiawei Zhang , Yizhou Sun , Philip S. Yu

The ability to find short representations, i.e. to compress data, is crucial for many intelligent systems. We present a theory of incremental compression showing that arbitrary data strings, that can be described by a set of features, can…

Information Theory · Computer Science 2020-09-15 Arthur Franz , Oleksandr Antonenko , Roman Soletskyi

The principle of similarity, or homophily, is often used to explain patterns observed in complex networks such as transitivity and the abundance of triangles (3-cycles). However, many phenomena from division of labor to protein-protein…

Physics and Society · Physics 2022-10-12 Szymon Talaga , Andrzej Nowak

Statistical laws describe regular patterns observed in diverse scientific domains, ranging from the magnitude of earthquakes (Gutenberg-Richter law) and metabolic rates in organisms (Kleiber's law), to the frequency distribution of words in…

Physics and Society · Physics 2025-02-14 Eduardo G. Altmann

The frequencies at which individual words occur across languages follow power law distributions, a pattern of findings known as Zipf's law. A vast literature argues over whether this serves to optimize the efficiency of human communication,…

Computation and Language · Computer Science 2020-01-16 Michael Ramscar
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