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Computed tomography (CT) is a widely used non-invasive diagnostic method in various fields, and recent advances in deep learning have led to significant progress in CT image reconstruction. However, the lack of large-scale, open-access…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Maximilian B. Kiss , Ander Biguri , Zakhar Shumaylov , Ferdia Sherry , K. Joost Batenburg , Carola-Bibiane Schönlieb , Felix Lucka

Medical imaging modalities have revolutionized health-care approaches by offering a better understanding of the human anatomy. Discovery of x-rays allowed the exploiting of the micro-scaled information of human anatomy. Computed tomography…

Medical Physics · Physics 2018-09-18 Sanam Assili

Modern tomography involves gathering projection data from multiple directions and feeding them into a software algorithm for tomographic reconstruction. We focus our study on image reconstruction from Radon data in the setting of…

Numerical Analysis · Mathematics 2014-12-19 Maria Angela Narduzzo

Diffusion models have recently emerged as powerful priors for solving inverse problems. While computed tomography (CT) is theoretically a linear inverse problem, it poses many practical challenges. These include correlated noise, artifact…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Jiayang Shi , Daniel M. Pelt , K. Joost Batenburg

Nonlinear parametric inverse problems appear in many applications. Here, we focus on diffuse optical tomography (DOT) in medical imaging to recover unknown images of interest, such as cancerous tissue in a given medium, using a mathematical…

Numerical Analysis · Mathematics 2020-07-14 Selin Aslan , Eric de Sturler , Serkan Gugercin

The motivation of this work is the detection of cerebrovascular accidents by microwave tomographic imaging. This requires the solution of an inverse problem relying on a minimization algorithm (for example, gradient-based), where successive…

Computational Engineering, Finance, and Science · Computer Science 2020-03-23 P. -H. Tournier , I. Aliferis , M. Bonazzoli , M. de Buhan , M. Darbas , V. Dolean , F. Hecht , P. Jolivet , I. El Kanfoud , C. Migliaccio , F. Nataf , C. Pichot , S. Semenov

This work is concerned with applying iterative image reconstruction, based on constrained total-variation minimization, to low-intensity X-ray CT systems that have a high sampling rate. Such systems pose a challenge for iterative image…

Medical Physics · Physics 2016-11-17 Emil Y. Sidky , Rick Chartrand , Yuval Duchin , Christer Ullberg , Xiaochuan Pan

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

In many modern imaging applications the desire to reconstruct high resolution images, coupled with the abundance of data from acquisition using ultra-fast detectors, have led to new challenges in image reconstruction. A main challenge is…

Numerical Analysis · Mathematics 2020-06-24 Julianne Chung , Matthias Chung , J. Tanner Slagel , Luis Tenorio

We study iterative signal reconstruction in computed tomography (CT), wherein measurements are produced by a linear transformation of the unknown signal followed by an exponential nonlinear map. Approaches based on pre-processing the data…

Optimization and Control · Mathematics 2024-07-19 Vasileios Charisopoulos , Rebecca Willett

Multidimensional imaging, capturing image data in more than two dimensions, has been an emerging field with diverse applications. Due to the limitation of two-dimensional detectors in obtaining the high-dimensional image data, computational…

Image and Video Processing · Electrical Eng. & Systems 2020-06-16 Didem Dogan , Figen S. Oktem

In this paper we present a generalized Deep Learning-based approach for solving ill-posed large-scale inverse problems occuring in medical image reconstruction. Recently, Deep Learning methods using iterative neural networks and cascaded…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Andreas Kofler , Markus Haltmeier , Tobias Schaeffter , Marc Kachelrieß , Marc Dewey , Christian Wald , Christoph Kolbitsch

The reconstruction of an unknown quantity from noisy measurements is a mathematical problem relevant in most applied sciences, for example, in medical imaging, radar inverse scattering, or astronomy. This underlying mathematical problem is…

Optimization and Control · Mathematics 2025-10-14 Nina M. Gottschling , David Iagaru , Jakob Gawlikowski , Ioannis Sgouralis

In this paper, we propose a novel deep convolutional neural network (CNN)-based algorithm for solving ill-posed inverse problems. Regularized iterative algorithms have emerged as the standard approach to ill-posed inverse problems in the…

Computer Vision and Pattern Recognition · Computer Science 2018-09-11 Kyong Hwan Jin , Michael T. McCann , Emmanuel Froustey , Michael Unser

This work is concerned with the following fundamental question in scientific machine learning: Can deep-learning-based methods solve noise-free inverse problems to near-perfect accuracy? Positive evidence is provided for the first time,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-13 Martin Genzel , Ingo Gühring , Jan Macdonald , Maximilian März

An extremely common bottleneck encountered in statistical learning algorithms is inversion of huge covariance matrices, examples being in evaluating Gaussian likelihoods for a large number of data points. We propose general parallel…

Methodology · Statistics 2013-12-09 Anjishnu Banerjee , Joshua Vogelstein , David Dunson

Computed Tomography (CT) has been widely adopted in medicine and it is increasingly being used in scientific and industrial applications. Parallelly, research in different mathematical areas concerning discrete inverse problems has led to…

The dose of X-ray radiation and the scanning time are crucial factors in computed tomography (CT) for clinical applications. In this work, we introduce a multi-source static CT imaging system designed to rapidly acquire sparse view and…

Medical Physics · Physics 2025-01-03 Ziju Shen , Haimiao Zhang , Bin Dong , Jun Qiu , Yunxiang Li , Zhili Cui

Most existing learning-based methods for solving imaging inverse problems can be roughly divided into two classes: iterative algorithms, such as plug-and-play and diffusion methods leveraging pretrained denoisers, and unrolled architectures…

Image and Video Processing · Electrical Eng. & Systems 2026-03-31 Matthieu Terris , Samuel Hurault , Maxime Song , Julian Tachella

Tomographic image sizes keep increasing over time and while the GPUs that compute the tomographic reconstruction are also increasing in memory size, they are not doing so fast enough to reconstruct the largest datasets. This problem is…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-05-10 Ander Biguri , Reuben Lindroos , Robert Bryll , Hossein Towsyfyan , Hans Deyhle , Richard Boardman , Mark Mavrogordato , Manjit Dosanjh , Steven Hancock , Thomas Blumensath