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Many of life's most fascinating phenomena emerge from interactions among many elements--many amino acids determine the structure of a single protein, many genes determine the fate of a cell, many neurons are involved in shaping our thoughts…

Quantitative Methods · Quantitative Biology 2011-11-28 Thierry Mora , William Bialek

Biological systems reach hierarchical complexity that has no counterpart outside the realm of biology. Undoubtedly, biological entities obey the fundamental physical laws. Can today's physics provide an explanatory framework for…

Statistical Mechanics · Physics 2022-10-12 Yuri I. Wolf , Mikhail I. Katsnelson , Eugene V. Koonin

Biological evolution is a complex blend of ever changing structural stability, variability and emergence of new phenotypes, niches, ecosystems. We wish to argue that the evolution of life marks the end of a physics world view of law…

Other Quantitative Biology · Quantitative Biology 2012-01-11 Giuseppe Longo , Maël Montévil , Stuart Kauffman

Droplet formation has emerged as an essential concept for the spatiotemporal organisation of biomolecules in cells. However, classical descriptions of droplet dynamics based on passive liquid-liquid phase separation cannot capture the…

Biological Physics · Physics 2025-11-14 David Zwicker , Oliver W. Paulin , Cathelijne ter Burg

In this essay the ontological structure of reality is explored. The question of reducibility of biology to physics is considered in the context of their ultimate principles. It is shown that biology is an ontologically autonomous science…

General Physics · Physics 2007-05-23 A. Grandpierre

This short text summarizes the work in biology proposed in our book, Perspectives on Organisms, where we analyse the unity proper to organisms by looking at it from different viewpoints. We discuss the theoretical roles of biological time,…

Other Computer Science · Computer Science 2019-03-14 Giuseppe Longo , Maël Montévil

The history of life on Earth and in other potential life-bearing planetary platforms is deeply linked to the history of the universe. Since life as we know it relies on chemical elements forged in dying heavy stars, the universe needs to be…

Popular Physics · Physics 2015-06-04 Marcelo Gleiser

We survey some of the philosophical challenges and pitfalls within origins research. Several of these challenges exhibit circularities, paradoxes, or anthropic biases. We present origins approaches in terms of three broad categories:…

Popular Physics · Physics 2023-03-15 Stuart Bartlett , Michael L Wong

A natural phenomenon occurring in a living system is an outcome of the dynamics of the specific biological network underlying the phenomenon. The collective dynamics have both deterministic and stochastic components. The stochastic nature…

Statistical Mechanics · Physics 2023-09-01 Indrani Bose

This paper explores the idea that information is an essential and distinctive feature of living systems. Unlike non-living systems, living systems actively acquire, process, and use information about their environments to respond to…

Apparent biodiversity on earth exists only if we compare different species separated from their environments. Meanwhile coexisting species have to be identical in terms of energetic interactions. Consider the biosphere as a network of…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Balciunas

Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that cannot be explained on the single molecule level. For example,…

Biological Physics · Physics 2009-06-09 Thomas Heimburg

We propose a novel definition of life in terms of which its emergence in the universe is expected, and its ever-creative open-ended evolution is entailed by no law. Living organisms are Kantian Wholes that achieve Catalytic Closure,…

Populations and Evolution · Quantitative Biology 2024-04-11 Stuart Kauffman , Andrea Roli

The claim that life is an emergent phenomenon exhibiting novel properties and principles is often criticized for being in conflict with causal closure at the microscopic level. I argue that advances in cosmological theory suggesting an…

Astrophysics · Physics 2007-05-23 P. C. W. Davies

Along with weaving together observations, experiments, and theoretical constructs into a coherent mesh of understanding of the world around us, physics over its past five centuries has continuously refined the base concepts on which the…

History and Philosophy of Physics · Physics 2017-04-05 A. R. P. Rau

Darwin's hypothesis that all extant life forms are descendants of a last common ancestor cell and diversification of life forms results from gradual mutation plus natural selection represents a mainstream view that has influenced biology…

Populations and Evolution · Quantitative Biology 2008-12-13 Shi V. Liu

We argue for a convergence of crystallography, materials science and biology, that will come about through asking materials questions about biology and biological questions about materials, illuminated by considerations of information. The…

Adaptation and Self-Organizing Systems · Physics 2012-07-18 Julyan H. E. Cartwright , Alan L. Mackay

We extend the concept that life is an informational phenomenon, at every level of organisation, from molecules to the global ecological system. According to this thesis: (a) living is information processing, in which memory is maintained by…

Information Theory · Computer Science 2014-02-17 Keith D. Farnsworth , John Nelson , Carlos Gershenson

Biological phenomena differ significantly from physical phenomena. At the heart of this distinction is the fact that biological entities have computational abilities and thus they are inherently difficult to predict. This is the reason why…

Molecular Networks · Quantitative Biology 2009-09-29 Pau Fernandez , Ricard V. Sole

Biofilms are complex, self-organized consortia of microorganisms that produce a functional, protective matrix of biomolecules. Physically, the structure of a biofilm can be described as an entangled polymer network which grows and changes…

Biological Physics · Physics 2016-11-08 Marco G. Mazza