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Two crucial for the breakdown of the master equation arguments are put forward. The first one is related to the violence of a fundamental requirement to the notion of state (thermodynamical) variable, namely: a state variable is defined…

Statistical Mechanics · Physics 2007-05-23 Maria K. Koleva

Quantitative studies of cell metabolism are often based on large chemical reaction network models. A steady state approach is suited to analyze phenomena on the timescale of cell growth and circumvents the problem of incomplete experimental…

Molecular Networks · Quantitative Biology 2019-02-20 A. De Martino , D. De Martino , E. Marinari

We consider a Reinforcement Learning setup where an agent interacts with an environment in observation-reward-action cycles without any (esp.\ MDP) assumptions on the environment. State aggregation and more generally feature reinforcement…

Artificial Intelligence · Computer Science 2014-07-15 Marcus Hutter

We outline the construction of a molecular system that could, in principle, implement a thermodynamically reversible Universal Turing Machine (UTM). By proposing a concrete-albeit idealised-design and operational protocol, we reveal…

Statistical Mechanics · Physics 2021-02-09 Rory A. Brittain , Nick S. Jones , Thomas E. Ouldridge

In this paper, we study the quantity of computational resources (state machine states and/or probabilistic transition precision) needed to solve specific problems in a single hop network where nodes communicate using only beeps. We begin by…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-08-18 Seth Gilbert , Calvin Newport

We examine the possible states of subsystems of a system of bits or qubits. In the classical case (bits), this means the possible marginal distributions of a probability distribution on a finite number of binary variables; we give necessary…

Quantum Physics · Physics 2015-06-26 Paul Butterley , Anthony Sudbery , Jason Szulc

We study the informational underpinnings of thermodynamics and statistical mechanics, using an abstract framework, general probabilistic theories, capable of describing arbitrary physical theories. This allows one to abstract the…

Quantum Physics · Physics 2019-01-25 Carlo Maria Scandolo

The reduction criterion is a well known necessary condition for separable states, and states violating this condition are entangled and also 1-distillable. In this paper we introduce a new set of necessary conditions for separability of…

Quantum Physics · Physics 2009-11-11 William Hall

For quantum many-body systems in one dimension, computational complexity theory reveals that the evaluation of ground-state energy remains elusive on quantum computers, contrasting the existence of a classical algorithm for temperatures…

Statistical Mechanics · Physics 2024-06-11 Atsushi Iwaki , Chisa Hotta

Digital computers implement computations using circuits, as do many naturally occurring systems (e.g., gene regulatory networks). The topology of any such circuit restricts which variables may be physically coupled during the operation of a…

Statistical Mechanics · Physics 2023-07-26 David Hilton Wolpert , Artemy Kolchinsky

In the case of quantum systems interacting with multiple environments, the time-evolution of the reduced density matrix is described by the Liouvillian. For a variety of physical observables, the long-time limit or steady state solution is…

Quantum Physics · Physics 2022-01-05 Rodrigo A. Vargas-Hernández , Ricky T. Q. Chen , Kenneth A. Jung , Paul Brumer

A key issue of current quantum advantage experiments is that their verification requires a full classical simulation of the ideal computation. This limits the regime in which the experiments can be verified to precisely the regime in which…

Quantum Physics · Physics 2025-10-08 Abhinav Deshpande , Bill Fefferman , Soumik Ghosh , Michael Gullans , Dominik Hangleiter

Understanding the thermodynamics of the duplication process is a fundamental step towards a comprehensive physical theory of biological systems. However, the immense complexity of real cells obscures the fundamental tensions between energy…

Statistical Mechanics · Physics 2018-12-07 Bernat Corominas-Murtra

Thermodynamic cost of communication is a major factor in the thermodynamic cost of real-world computers, both biological and digital. Despite its importance, the fundamental principles underlying this cost remain poorly understood. This…

Statistical Mechanics · Physics 2025-12-29 Abhishek Yadav , David Wolpert

Information-theoretic approaches provide a promising avenue for extending the laws of thermodynamics to the nanoscale. Here, we provide a general fundamental lower limit, valid for systems with an arbitrary Hamiltonian and in contact with…

Quantum Physics · Physics 2018-05-08 Philippe Faist , Renato Renner

We consider bipartite quantum state discrimination and present a quantum data-hiding scheme utilizing an orthogonal separable state ensemble. Using a bound on local minimum-error discrimination, we provide a sufficient condition for the…

Quantum Physics · Physics 2025-05-08 Donghoon Ha , Jeong San Kim

A complete characterization of the set of states that can be achieved through Thermal Processes (TP) is given by describing all vertices, edges and facets of the allowed set of states in the language of thermomajorization curves. TPs are…

Quantum Physics · Physics 2019-04-17 Paweł Mazurek

In analogy to Brownian computers we explicitly show how to construct stochastic models, which mimic the behaviour of a general purpose computer (a Turing machine). Our models are discrete state systems obeying a Markovian master equation,…

Statistical Mechanics · Physics 2015-10-13 Philipp Strasberg , Javier Cerrillo , Gernot Schaller , Tobias Brandes

From economics point of view, we investigate a new optimal control problem driven by a stochastic differential equation with a multi-time states cost functional. By constructing a series of first-order adjoint equations, we establish the…

Optimization and Control · Mathematics 2016-09-15 Shuzhen Yang

Model checking has been proposed as a formal verification approach for analyzing computer-based and cyber-physical systems. The state space explosion problem is the main obstacle for applying this approach for sophisticated systems.…

Performance · Computer Science 2023-07-18 Mohammadsadegh Mohagheghi , Khayyam Salehi