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Ecosystems, which are intricate amalgams of biological communities and their surrounding environments, continually evolve under the influence of their myriad interactions. The world is currently facing intensifying environmental…

Biological Physics · Physics 2023-11-23 Ikumi Kobayashi

Enzymes are on the front lines of evolution. All living organisms rely on highly efficient, specific enzymes for growth, sustenance, and reproduction; and many diseases are a consequence of a mutation on an enzyme that affects its catalytic…

Molecular Networks · Quantitative Biology 2009-01-07 Nilou Ataie

The recent discovery of universal principles underlying many complex networks occurring across a wide range of length scales in the biological world has spurred physicists in trying to understand such features using techniques from…

Biological Physics · Physics 2015-05-13 Sitabhra Sinha

Empirical evidence suggesting that living systems might operate in the vicinity of critical points, at the borderline between order and disorder, has proliferated in recent years, with examples ranging from spontaneous brain activity to…

Statistical Mechanics · Physics 2014-07-25 Jorge Hidalgo , Jacopo Grilli , Samir Suweis , Miguel A. Munoz , Jayanth R. Banavar , Amos Maritan

This chapter is about Complexity and Spatial Dynamics in Urban Systems. Strong inequalities in the size of cities and the apparent difficulty of limiting their growth raise practical issues for spatial planning. At a time when new…

Physics and Society · Physics 2020-10-29 Juste Raimbault , Denise Pumain

Scaling laws illuminate Nature's fundamental biological principles and guide bioinspired materials and structural designs. In simple cases they are based on the fundamental principle that all laws of nature remain unchanged (i.e.,…

Biological Physics · Physics 2025-02-18 Huan Liu , Shashank Priya , Richard D. James

Eukaryote genomes contain excessively introns, inter-genic and other non-genic sequences that appear to have no vital functional role or phenotype manifestation. Their existence, a long-standing puzzle, is viewed from the principle of…

Populations and Evolution · Quantitative Biology 2008-07-08 Salla Jaakkola , Sedeer El-Showk , Arto Annila

Extremal principles are fundamental in our interpretation of phenomena in nature. One of the best known examples is the second law of thermodynamics, governing most physical and chemical systems and stating the continuous increase of…

Statistical Mechanics · Physics 2007-05-23 Dirk Helbing , Tamas Vicsek

Statistical physics can describe the behavior of microbial populations consisting of many heterogeneous individuals. A direct consequence is the existence of phase transitions, where the behavior of a population changes discontinuously upon…

Populations and Evolution · Quantitative Biology 2026-04-20 Kaan Öcal , Syrine Ghrabli , Michael P. H. Stumpf

The evolution in coding DNA sequences brings new flexibility and freedom to the codon words, even as the underlying nucleotides get significantly ordered. These curious contra-rules of gene organisation are observed from the distribution of…

Biological Physics · Physics 2007-05-23 Sujay Chattopadhyay , William A. Kanner , Jayprokas Chakrabarti

Biological aging is characterized by an age-dependent increase in the probability of death and by a decrease in the reproductive capacity. Individual age-dependent rates of survival and reproduction have a strong impact on population…

Populations and Evolution · Quantitative Biology 2016-02-03 Arian Šajina , Dario Riccardo Valenzano

Microbial ecosystems are commonly modeled by fixed interactions between species in steady exponential growth states. However, microbes often modify their environments so strongly that they are forced out of the exponential state into…

Populations and Evolution · Quantitative Biology 2024-01-08 Avaneesh V. Narla , Terence Hwa , Arvind Murugan

Theoretical physics is the search for simple and universal mathematical descriptions of the natural world. In contrast, much of modern biology is an exploration of the complexity and diversity of life. For many, this contrast is prima facie…

Biological Physics · Physics 2024-01-23 William Bialek

Performance evolution of a number of complex scientific and technical systems demonstrate exponential progress with time exp(+t/C) . The speed of progress C - a measure of difficulty and complexity - is analyzed for high energy elementary…

Physics and Society · Physics 2011-05-05 Vladimir Shiltsev

Complex systems are characterized by specific time-dependent interactions among their many constituents. As a consequence they often manifest rich, non-trivial and unexpected behavior. Examples arise both in the physical and non-physical…

Physics and Society · Physics 2018-11-21 Yurij Holovatch , Ralph Kenna , Stefan Thurner

The margins within the geographic range of species are often specific in terms of ecological and evolutionary processes, and can strongly influence the species' reaction to climate change. One of the frequently observed features at range…

Populations and Evolution · Quantitative Biology 2020-02-28 R. Juhász , B. Oborny

Evolution is the process of optimal adaptation of biological populations to their living environments. This is expressed via the concept of fitness, defined as relative reproductive success. However, it has been pointed out that this…

Populations and Evolution · Quantitative Biology 2025-04-17 Luís MA Bettencourt , Brandon J Grandison , Jordan T Kemp

We discuss general formation of complementary behaviors, functions and forms in biological species competing for resources. We call orthogonalization the related processes on macro and micro-level of a self-organized formation of…

Biological Physics · Physics 2007-05-23 Petr Kral

Well protected human and laboratory animal populations with abundant resources are evolutionary unprecedented. Physical approach, which takes advantage of their extensively quantified mortality, establishes that its dominant fraction yields…

Quantitative Methods · Quantitative Biology 2007-05-23 Mark Ya. Azbel'

After more than a century of concerted effort, physics still lacks basic principles of spontaneous self-organization. To appreciate why, we first state the problem, outline historical approaches, and survey the present state of the physics…

Statistical Mechanics · Physics 2023-11-27 Adam T. Rupe , James P. Crutchfield