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The fixed-X knockoff filter is a flexible framework for variable selection with false discovery rate (FDR) control in linear models with arbitrary design matrices (of full column rank) and it allows for finite-sample selective inference via…

Statistics Theory · Mathematics 2023-11-28 Mehrdad Pournaderi , Yu Xiang

We address challenges in variable selection with highly correlated data that are frequently present in finance, economics, but also in complex natural systems as e.g. weather. We develop a robustified version of the knockoff framework,…

Econometrics · Economics 2022-06-14 Konstantin Görgen , Abdolreza Nazemi , Melanie Schienle

Motivated by the gene co-expression pattern analysis, we propose a novel sample quantile-based contingency (squac) statistic to infer quantile associations conditioning on covariates. It features enhanced flexibility in handling variables…

Methodology · Statistics 2018-08-27 Jichun Xie , Ruosha Li

The knockoff filter of Barber and Candes (arXiv:1404.5609) is a flexible framework for multiple testing in supervised learning models, based on introducing synthetic predictor variables to control the false discovery rate (FDR). Using the…

Methodology · Statistics 2024-11-26 Yixiang Luo , William Fithian , Lihua Lei

Variable selection plays a crucial role in enhancing modeling effectiveness across diverse fields, addressing the challenges posed by high-dimensional datasets of correlated variables. This work introduces a novel approach namely Knockoff…

Machine Learning · Statistics 2025-01-31 Xiaochen Zhang , Yunfeng Cai , Haoyi Xiong

Cause-effect analysis is crucial to understand the underlying mechanism of a system. We propose to exploit model invariance through interventions on the predictors to infer causality in nonlinear multivariate systems of time series. We…

Machine Learning · Computer Science 2022-07-12 Wasim Ahmad , Maha Shadaydeh , Joachim Denzler

Controlled variable selection is an important analytical step in various scientific fields, such as brain imaging or genomics. In these high-dimensional data settings, considering too many variables leads to poor models and high costs,…

Methodology · Statistics 2023-10-17 Alexandre Blain , Bertrand Thirion , Olivier Grisel , Pierre Neuvial

Variable selection properties of procedures utilizing penalized-likelihood estimates is a central topic in the study of high dimensional linear regression problems. Existing literature emphasizes the quality of ranking of the variables by…

Statistics Theory · Mathematics 2022-04-28 Asaf Weinstein , Weijie J. Su , Małgorzata Bogdan , Rina F. Barber , Emmanuel J. Candès

Balancing false discovery rate (FDR) control with high statistical power remains a central challenge in high-dimensional variable selection. While several FDR-controlling methods have been proposed, many degrade the original data -- by…

Methodology · Statistics 2025-07-16 Changhu Wang , Ziheng Zhang , Jingyi Jessica Li

An increasing number of emerging applications in data science and engineering are based on multidimensional and structurally rich data. The irregularities, however, of high-dimensional data often compromise the effectiveness of standard…

Selecting important features that have substantial effects on the response with provable type-I error rate control is a fundamental concern in statistics, with wide-ranging practical applications. Existing knockoff filters, although shown…

Methodology · Statistics 2024-02-29 Jiaqi Gu , Zihuai He

As a paradigm for sequential decision making in unknown environments, reinforcement learning (RL) has received a flurry of attention in recent years. However, the explosion of model complexity in emerging applications and the presence of…

Machine Learning · Statistics 2025-07-22 Yuejie Chi , Yuxin Chen , Yuting Wei

Identifying signals that replicate across multiple studies is essential for establishing robust scientific evidence, yet existing methods for high-dimensional replicability analysis either rely on restrictive modeling assumptions, are…

Methodology · Statistics 2026-03-05 Haochen Lei , Yan Li , Hongyuan Cao

Given data $\mathbf{y}$ and $k$ covariates $\mathbf{x}_j$ one problem in linear regression is to decide which if any of the covariates to include when regressing the dependent variable $\mathbf{y}$ on the covariates $\mathbf{x}_j$. In this…

Methodology · Statistics 2019-04-02 Laurie Davies

In 2015, Barber and Candes introduced a new variable selection procedure called the knockoff filter to control the false discovery rate (FDR) and prove that this method achieves exact FDR control. Inspired by the work of Barber and Candes…

Methodology · Statistics 2019-07-23 Jiajie Chen , Anthony Hou , Thomas Y. Hou

We propose an approach to multivariate nonparametric regression that generalizes reduced rank regression for linear models. An additive model is estimated for each dimension of a $q$-dimensional response, with a shared $p$-dimensional…

Machine Learning · Statistics 2013-01-10 Rina Foygel , Michael Horrell , Mathias Drton , John Lafferty

Large-scale hypothesis testing is central to modern science, where controlling the False Discovery Rate (FDR) has become the standard approach to managing false positives across many simultaneous tests. Hypotheses rarely exist in isolation;…

Methodology · Statistics 2026-05-19 Binyamin Perets , Shie Mannor

Testing multiple hypotheses of conditional independence with provable error rate control is a fundamental problem with various applications. To infer conditional independence with family-wise error rate (FWER) control when only summary…

Methodology · Statistics 2023-10-17 Catherine Xinrui Yu , Jiaqi Gu , Zhaomeng Chen , Zihuai He

In reinforcement learning (RL), the consideration of multivariate reward signals has led to fundamental advancements in multi-objective decision-making, transfer learning, and representation learning. This work introduces the first…

Machine Learning · Computer Science 2024-09-05 Harley Wiltzer , Jesse Farebrother , Arthur Gretton , Mark Rowland

The generalized linear models (GLM) have been widely used in practice to model non-Gaussian response variables. When the number of explanatory features is relatively large, scientific researchers are of interest to perform controlled…

Methodology · Statistics 2020-07-03 Chenguang Dai , Buyu Lin , Xin Xing , Jun S. Liu