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Magnetic fields interact with biological cells affecting them in variety of ways which are usually hard to predict. Among them, it was observed that strong fields can align dividing cells in a preferred direction. It was also demonstrated…

Medical Physics · Physics 2015-09-28 Stoyan Stoynev

The use of drugs or radiation to attack cancerous cells often leaves the treatment material within the body where it could affect healthy cells or damages healthy tissue; as is the case with traditional invasive surgery. An alternative…

Biological Physics · Physics 2022-06-14 Derek Michael Forrester

The possible disruption of a microtubule during mitosis can control the duplication of a cancer cell. Cancer detection and treatment may be possible based on the detection and control of microtubule mechanical oscillations in cells through…

Quantum Physics · Physics 2017-07-19 Sh. Barzanjeh , V. Salari , J. A. Tuszynski , M. Cifra , C. Simon

The tumour microenvironment (TME) strongly influences tumorigenesis and metastasis. Two of the most characterized properties of the TME are acidosis and hypoxia, both of which are considered hallmarks of tumours as well as critical factors…

Current methods for capturing circulating tumor cells (CTCs) are based on the overexpression of cytokeratin (CK) or epithelial cell-adhesion molecule (EpCAM) on cancer cells. However, during the process of metastasis, tumor cells undergo…

Cancer cells can acquire a spectrum of stable hybrid epithelial/mesenchymal (E/M) states during epithelial-mesenchymal transition (EMT). Cells in these hybrid E/M phenotypes often combine epithelial and mesenchymal features and tend to…

Cell Behavior · Quantitative Biology 2019-04-17 Dongya Jia , Xuefei Li , Federico Bocci , Shubham Tripathi , Youyuan Deng , Mohit Kumar Jolly , Jose N. Onuchic , Herbert Levine

A mathematical model is presented for predicting magnetic targeting of multifunctional carrier particles that are designed to deliver therapeutic agents to malignant tissue in vivo. These particles consist of a nonmagnetic core material…

Biological Physics · Physics 2015-06-26 E. J. Furlani , E. P. Furlani

Electrospinning is historically related to tissue engineering due to its ability to produce nano-/microscale fibrous materials with mechanical and functional properties that are extremely similar to those of the extracellular matrix of…

Electropermeabilization is a clinical technique in cancer treatment to locally stimulate the cell metabolism. It is based on electrical fields that change the properties of the cell membrane. With that, cancer treatment can reach the cell…

Analysis of PDEs · Mathematics 2016-03-03 Habib Ammari , Thomas Widlak , Wenlong Zhang

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

The ability to control electromagnetic fields on the subwavelength scale could open exciting new venues in many fields of science. Transformation optics provides one way to attain such control through the local variation of the permittivity…

Optics · Physics 2014-05-13 Bo Liu , Eric J. Heller

We review the field of cavity optomechanics, which explores the interaction between electromagnetic radiation and nano- or micromechanical motion. This review covers the basics of optical cavities and mechanical resonators, their mutual…

Mesoscale and Nanoscale Physics · Physics 2015-01-05 Markus Aspelmeyer , Tobias J. Kippenberg , Florian Marquardt

Tumor Treating Fields (TTFields) is a non-invasive anticancer modality that utilizes alternating electric fields to disrupt cancer cell division and growth. While generally well-tolerated with minimal side effects, traditional TTFields…

Medical Physics · Physics 2024-07-11 Minmin Wang , Xu Xie , Yuxi Guo , Liying Zhu , Yue Lan , Haitang Yang , Yun Pan , Guangdi Chen , Shaomin Zhang , Maomao Zhang

Magnetic hyperthermia is a new type of cancer treatment designed for overcoming resistance to chemotherapy during the treatment of solid, inaccessible human tumors. The main challenge of this technology is increasing the local tumoral…

Tissues and Organs · Quantitative Biology 2016-11-09 Beatriz Sanz , M. Pilar Calatayud , Teobaldo E. Torres , Mónica L. Fanarraga , M. Ricardo Ibarra , Gerardo F. Goya

Imaging dynamical processes at interfaces and on the nanoscale is of great importance throughout science and technology. While light-optical imaging techniques often cannot provide the necessary spatial resolution, electron-optical…

Purpose of review: The epithelial-Mesenchymal Transition (EMT) and the generation of Cancer Stem Cells (CSC) are two fundamental aspects contributing to tumor growth, acquisition of resistance to therapy, formation of metastases, and tumor…

Molecular Networks · Quantitative Biology 2018-11-07 Federico Bocci , Herbert Levine , José Nelson Onuchic , Mohit Kumar Jolly

Cavity optomechanics aims to establish optical control over vibrations of mechanical systems, to heat, cool or to drive them toward coherent, or nonclassical states. This field was recently extended to include molecular optomechanics, which…

Quantum Physics · Physics 2023-06-28 Mikołaj K. Schmidt , Michael J. Steel

We propose to use a compound of magnetic nanoparticles (20-100 nm) embedded in a flexible polymer (Polydimethylsiloxane PDMS) to filter circulating tumor cells (CTCs). The analysis of CTCs is an emerging tool for cancer biology research and…

The optical cross sections of plasmonic nanoparticles are intricately linked to the morphology of the particle. If this connection can be made accurately enough, it would become possible to determine a particles shape solely from its…

Background and controlled electromagnetic radiation (EMR) on biological cells and tissues induces thermal, non-thermal, and dielectric property change. After EMR interaction with cells/tissues the resulting signal is used for imaging,…

Biological Physics · Physics 2020-12-24 Biswadev Roy , Suryakant Niture , Marvin H. Wu
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