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Over the past decade, neural networks have been successful at making predictions from biological sequences, especially in the context of regulatory genomics. As in other fields of deep learning, tools have been devised to extract features…

Genomics · Quantitative Biology 2022-12-27 Antoine Villié , Philippe Veber , Yohann de Castro , Laurent Jacob

Heralded by the initial success in speech recognition and image classification, learning-based approaches with neural networks, commonly referred to as deep learning, have spread across various fields. A primitive form of a neural network…

Robotics · Computer Science 2024-09-02 Takuma Yoneda

Recent work on mode connectivity in the loss landscape of deep neural networks has demonstrated that the locus of (sub-)optimal weight vectors lies on continuous paths. In this work, we train a neural network that serves as a hypernetwork,…

Machine Learning · Statistics 2019-05-09 Lior Deutsch , Erik Nijkamp , Yu Yang

Neurodegenerative diseases are characterized by the accumulation of misfolded proteins and widespread disruptions in brain function. Computational modeling has advanced our understanding of these processes, but efforts have traditionally…

Recent advances in network science, applied to \textit{in vivo} brain recordings, have paved the way for better understanding of the structure and function of the brain. However, despite its obvious usefulness in neuroscience, traditional…

Neurons and Cognition · Quantitative Biology 2025-02-03 Vesna Vuksanovic

It is tempting to think that machines are less prone to unfairness and prejudice. However, machine learning approaches compute their outputs based on data. While biases can enter at any stage of the development pipeline, models are…

Computer Vision and Pattern Recognition · Computer Science 2020-12-07 Patrick Esser , Robin Rombach , Björn Ommer

Neuroscience is undergoing dramatic progress because of the vast data streams derived from the new technologies product of the BRAIN initiative and other enterprises. As any other scientific field, neuroscience benefits from having clear…

Neurons and Cognition · Quantitative Biology 2022-09-22 Horacio G. Rotstein , Fidel Santamaria

Complex networks are frequently employed to model physical or virtual complex systems. When certain entities exist across multiple systems simultaneously, unveiling their corresponding relationships across the networks becomes crucial. This…

Physics and Society · Physics 2025-04-16 Rui Tang , Ziyun Yong , Shuyu Jiang , Xingshu Chen , Yaofang Liu , Yi-Cheng Zhang , Gui-Quan Sun , Wei Wang

Deciphering the underpinnings of the dynamical processes leading to information transmission, processing, and storing in the brain is a crucial challenge in neuroscience. An inspiring but speculative theoretical idea is that such dynamics…

Statistical Mechanics · Physics 2023-07-21 Guillermo B. Morales , Serena Di Santo , Miguel A. Muñoz

Recurrent neural networks (RNNs) are widely used throughout neuroscience as models of local neural activity. Many properties of single RNNs are well characterized theoretically, but experimental neuroscience has moved in the direction of…

Machine Learning · Computer Science 2023-01-31 Leo Kozachkov , Michaela Ennis , Jean-Jacques Slotine

Generative adversarial networks (GANs) provide an algorithmic framework for constructing generative models with several appealing properties: they do not require a likelihood function to be specified, only a generating procedure; they…

Machine Learning · Statistics 2017-02-28 Shakir Mohamed , Balaji Lakshminarayanan

The present paper aims to demonstrate the usage of Convolutional Neural Networks as a generative model for stochastic processes, enabling researchers from a wide range of fields (such as quantitative finance and physics) to develop a…

Machine Learning · Statistics 2018-01-12 Fernando Fernandes Neto

Neural networks have achieved remarkable success across various fields. However, the lack of interpretability limits their practical use, particularly in critical decision-making scenarios. Post-hoc interpretability, which provides…

Machine Learning · Computer Science 2025-11-21 Yang Ji , Ying Sun , Yuting Zhang , Zhigaoyuan Wang , Yuanxin Zhuang , Zheng Gong , Dazhong Shen , Chuan Qin , Hengshu Zhu , Hui Xiong

Multilayer networks allow one to represent diverse and coupled connectivity patterns --- e.g., time-dependence, multiple subsystems, or both --- that arise in many applications and which are difficult or awkward to incorporate into standard…

Social and Information Networks · Computer Science 2020-05-06 Marya Bazzi , Lucas G. S. Jeub , Alex Arenas , Sam D. Howison , Mason A. Porter

As the discipline has evolved, research in machine learning has been focused more and more on creating more powerful neural networks, without regard for the interpretability of these networks. Such "black-box models" yield state-of-the-art…

Machine Learning · Computer Science 2021-09-02 Lachlan O'Neill , Simon Angus , Satya Borgohain , Nader Chmait , David L. Dowe

Genetic Regulatory Networks (GRNs) plays a vital role in the understanding of complex biological processes. Modeling GRNs is significantly important in order to reveal fundamental cellular processes, examine gene functions and understanding…

Computational Engineering, Finance, and Science · Computer Science 2012-05-10 Khalid Raza , Rafat Parveen

A central idea in understanding brains and building artificial intelligence is that structure determines function. Yet, how the brain's complex structure arises from a limited set of genetic instructions remains a key question. The ultra…

Neurons and Cognition · Quantitative Biology 2026-01-28 Xingyu Liu , Yubin Li , Guozhang Chen

Generative methods (Gen-AI) are reviewed with a particular goal of solving tasks in machine learning and Bayesian inference. Generative models require one to simulate a large training dataset and to use deep neural networks to solve a…

Computation · Statistics 2025-05-20 Maria Nareklishvili , Nick Polson , Vadim Sokolov

This article serves as an introduction to the study of networks of social systems. First, we introduce the reader to key mathematical tools to study social networks, including mathematical representations of networks and essential…

Physics and Society · Physics 2023-02-03 Heather Z. Brooks

Generative models learn the distribution of data from a sample dataset and can then generate new data instances. Recent advances in deep learning has brought forth improvements in generative model architectures, and some state-of-the-art…

Cryptography and Security · Computer Science 2021-07-30 Luke A. Bauer , Vincent Bindschaedler