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Cancer cell response to targeted therapy arises from complex molecular interactions, making single omics insufficient for accurate prediction. This study develops a model to predict Dabrafenib sensitivity by integrating multiple omics…

Early diagnosis of pathological invasiveness of pulmonary adenocarcinomas using computed tomography (CT) imaging would alter the course of treatment of adenocarcinomas and subsequently improve the prognosis. Most of the existing systems use…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Xiang Li , Jiechao Ma , Hongwei Li

Convolutional neural networks (CNNs) have achieved the state-of-the-art performance in skin lesion analysis. Compared with single CNN classifier, combining the results of multiple classifiers via fusion approaches shows to be more effective…

Computer Vision and Pattern Recognition · Computer Science 2020-09-10 Di Zhuang , Keyu Chen , J. Morris Chang

Omics fusion has emerged as a crucial preprocessing approach in the field of medical image processing, providing significant assistance to several studies. One of the challenges encountered in the integration of omics data is the presence…

Quantitative Methods · Quantitative Biology 2025-02-17 Jiabao Sheng , SaiKit Lam , Jiang Zhang , Yuanpeng Zhang , Jing Cai

The application of natural language processing (NLP) to cancer pathology reports has been focused on detecting cancer cases, largely ignoring precancerous cases. Improving the characterization of precancerous adenomas assists in developing…

Machine Learning · Computer Science 2022-12-13 Yizhen Zhong , Jiajie Xiao , Thomas Vetterli , Mahan Matin , Ellen Loo , Jimmy Lin , Richard Bourgon , Ofer Shapira

Face clustering is an essential tool for exploiting the unlabeled face data, and has a wide range of applications including face annotation and retrieval. Recent works show that supervised clustering can result in noticeable performance…

Computer Vision and Pattern Recognition · Computer Science 2020-04-06 Lei Yang , Dapeng Chen , Xiaohang Zhan , Rui Zhao , Chen Change Loy , Dahua Lin

Prior work on diagnosing Alzheimer's disease from magnetic resonance images of the brain established that convolutional neural networks (CNNs) can leverage the high-dimensional image information for classifying patients. However, little…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 Sebastian Pölsterl , Tom Nuno Wolf , Christian Wachinger

Multi-omics research has enhanced our understanding of cancer heterogeneity and progression. Investigating molecular data through multi-omics approaches is crucial for unraveling the complex biological mechanisms underlying cancer, thereby…

Breast cancer classification remains a challenging task due to inter-class ambiguity and intra-class variability. Existing deep learning-based methods try to confront this challenge by utilizing complex nonlinear projections. However, these…

Computer Vision and Pattern Recognition · Computer Science 2020-10-08 Xiao Kang , Xingbo Liu , Xiushan Nie , Xiaoming Xi , Yilong Yin

The analysis of multi-modality positron emission tomography and computed tomography (PET-CT) images for computer aided diagnosis applications requires combining the sensitivity of PET to detect abnormal regions with anatomical localization…

Computer Vision and Pattern Recognition · Computer Science 2019-10-29 Ashnil Kumar , Michael Fulham , Dagan Feng , Jinman Kim

Functional magnetic resonance imaging (fMRI) data have become increasingly available and are useful for describing functional connectivity (FC), the relatedness of neuronal activity in regions of the brain. This FC of the brain provides…

Machine Learning · Statistics 2020-10-14 Andrew DiLernia , Karina Quevedo , Jazmin Camchong , Kelvin Lim , Wei Pan , Lin Zhang

We propose a new multi-network-based strategy to integrate different layers of genomic information and use them in a coordinate way to identify driving cancer genes. The multi-networks that we consider combine transcription factor…

Molecular Networks · Quantitative Biology 2015-12-10 Laura Cantini , Enzo Medico , Santo Fortunato , Michele Caselle

Nuanced cancer patient care is needed, as the development and clinical course of cancer is multifactorial with influences from the general health status of the patient, germline and neoplastic mutations, co-morbidities, and environment. To…

Quantitative Methods · Quantitative Biology 2023-09-26 Ali Firooz , Avery T. Funkhouser , Julie C. Martin , W. Jeffery Edenfield , Homayoun Valafar , Anna V. Blenda

Fuzzy C-Means (FCM) is a widely used clustering method. However, FCM and its many accelerated variants have low efficiency in the mid-to-late stage of the clustering process. In this stage, all samples are involved in the update of their…

Machine Learning · Computer Science 2023-02-15 Dong Li , Shuisheng Zhou , Witold Pedrycz

The integration of quantum machine learning with classical deep learning offers promising avenues for medical image analysis by mapping data into high-dimensional Hilbert spaces. However, effectively unifying these distinct paradigms…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasmin Rodrigues Sobrinho , João Renato Ribeiro Manesco , João Paulo Papa

Cancer is responsible for millions of deaths worldwide every year. Although significant progress hasbeen achieved in cancer medicine, many issues remain to be addressed for improving cancer therapy.Appropriate cancer patient stratification…

Machine Learning · Computer Science 2021-01-18 David Oniani , Chen Wang , Yiqing Zhao , Andrew Wen , Hongfang Liu , Feichen Shen

Motivation: How do we integratively analyze large-scale multi-platform genomic data that are high dimensional and sparse? Furthermore, how can we incorporate prior knowledge, such as the association between genes, in the analysis…

Machine Learning · Computer Science 2017-11-28 Dongjin Choi , Lee Sael

Federated learning (FL) is a distributed learning method that offers medical institutes the prospect of collaboration in a global model while preserving the privacy of their patients. Although most medical centers conduct similar medical…

Machine Learning · Computer Science 2022-07-08 Yousef Yeganeh , Azade Farshad , Johann Boschmann , Richard Gaus , Maximilian Frantzen , Nassir Navab

In order to explore the suitability of a fine-grained classification of journal articles by exploiting multiple sources of information, articles are organized in a two-layer multiplex. The first layer conveys similarities based on the…

Digital Libraries · Computer Science 2024-01-02 Alberto Baccini , Federica Baccini , Lucio Barabesi , Martina Cioni , Eugenio Petrovich , Daria Pignalosa

Despite technological and medical advances, the detection, interpretation, and treatment of cancer based on imaging data continue to pose significant challenges. These include inter-observer variability, class imbalance, dataset shifts,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Richard Osuala , Kaisar Kushibar , Lidia Garrucho , Akis Linardos , Zuzanna Szafranowska , Stefan Klein , Ben Glocker , Oliver Diaz , Karim Lekadir
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