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Diagnosing and cleaning data is a crucial step for building robust machine learning systems. However, identifying problems within large-scale datasets with real-world distributions is challenging due to the presence of complex issues such…

Machine Learning · Computer Science 2023-10-31 Jang-Hyun Kim , Sangdoo Yun , Hyun Oh Song

Semantic concept hierarchy is still under-explored for semantic segmentation due to the inefficiency and complicated optimization of incorporating structural inference into dense prediction. This lack of modeling semantic correlations also…

Computer Vision and Pattern Recognition · Computer Science 2018-03-19 Xiaodan Liang , Hongfei Zhou , Eric Xing

In this paper, we introduce a novel Distributed Markov Chain Monte Carlo (MCMC) inference method for the Bayesian Non-Parametric Latent Block Model (DisNPLBM), employing the Master/Worker architecture. Our non-parametric co-clustering…

Machine Learning · Statistics 2024-02-05 Reda Khoufache , Anisse Belhadj , Hanene Azzag , Mustapha Lebbah

Deep learning has deeply influenced protein science, enabling breakthroughs in predicting protein properties, higher-order structures, and molecular interactions. This paper introduces DeepProtein, a comprehensive and user-friendly deep…

Machine Learning · Computer Science 2025-06-17 Jiaqing Xie , Tianfan Fu

Mixed Integer Linear Programming (MILP) is a fundamental tool for modeling combinatorial optimization problems. Recently, a growing body of research has used machine learning to accelerate MILP solving. Despite the increasing popularity of…

Machine Learning · Computer Science 2024-10-29 Weimin Huang , Taoan Huang , Aaron M Ferber , Bistra Dilkina

Purpose: This study aimed to enhance protein sequence classification using natural language processing (NLP) techniques while addressing the impact of sequence similarity on model performance. We compared various machine learning and deep…

Quantitative Methods · Quantitative Biology 2025-05-26 Huma Perveen , Julie Weeds

Current AI-assisted protein design mainly utilizes protein sequential and structural information. Meanwhile, there exists tremendous knowledge curated by humans in the text format describing proteins' high-level functionalities. Yet,…

We propose a method for gene expression based analysis of cancer phenotypes incorporating network biology knowledge through unsupervised construction of computational graphs. The structural construction of the computational graphs is driven…

Molecular Networks · Quantitative Biology 2020-10-02 Paul Scherer , Maja Trȩbacz , Nikola Simidjievski , Zohreh Shams , Helena Andres Terre , Pietro Liò , Mateja Jamnik

Protein retrieval, which targets the deconstruction of the relationship between sequences, structures and functions, empowers the advancing of biology. Basic Local Alignment Search Tool (BLAST), a sequence-similarity-based algorithm, has…

Information Retrieval · Computer Science 2025-01-06 Yuxuan Wu , Xiao Yi , Yang Tan , Huiqun Yu , Guisheng Fan , Gaowei Zheng

Knowledge graphs have emerged as an important model for studying complex multi-relational data. This has given rise to the construction of numerous large scale but incomplete knowledge graphs encoding information extracted from various…

Machine Learning · Computer Science 2018-07-24 Rakshit Trivedi , Bunyamin Sisman , Jun Ma , Christos Faloutsos , Hongyuan Zha , Xin Luna Dong

Inspired by the increasing interest in self-organizing social opportunistic networks, we investigate the problem of distributed detection of unknown communities in dynamic random graphs. As a formal framework, we consider the dynamic…

Social and Information Networks · Computer Science 2014-07-10 Andrea Clementi , Miriam di Ianni , Giorgio Gambosi , Emanuele Natale , Riccardo Silvestri

Understanding biological processes, drug development, and biotechnological advancements requires a detailed analysis of protein structures and functions, a task that is inherently complex and time-consuming in traditional protein research.…

Artificial Intelligence · Computer Science 2025-04-21 Yijia Xiao , Edward Sun , Yiqiao Jin , Qifan Wang , Wei Wang

Healthcare domain generates a lot of unstructured and semi-structured text. Natural Language processing (NLP) has been used extensively to process this data. Deep Learning based NLP especially Large Language Models (LLMs) such as BERT have…

Computation and Language · Computer Science 2023-01-11 Kunal Suri , Atul Singh , Prakhar Mishra , Swapna Sourav Rout , Rajesh Sabapathy

The integration of multi-omic data is pivotal for understanding complex diseases, but its high dimensionality and noise present significant challenges. Graph Neural Networks (GNNs) offer a robust framework for analyzing large-scale…

Quantitative Methods · Quantitative Biology 2024-12-23 Heming Zhang , Di Huang , Yixin Chen , Fuhai Li

Proteins interact to form complexes to carry out essential biological functions. Computational methods have been developed to predict the structures of protein complexes. However, an important challenge in protein complex structure…

Machine Learning · Computer Science 2022-05-24 Xiao Chen , Alex Morehead , Jian Liu , Jianlin Cheng

The goal in network state prediction (NSP) is to classify the global state (label) associated with features embedded in a graph. This graph structure encoding feature relationships is the key distinctive aspect of NSP compared to classical…

Machine Learning · Computer Science 2019-04-02 Lin Zhang , Petko Bogdanov

Proteins are fundamental to biology, executing diverse functions through complex physicochemical interactions, and they hold transformative potential across medicine, materials science, and environmental applications. Protein Language…

Biomolecules · Quantitative Biology 2025-06-11 Logan Hallee , Nikolaos Rafailidis , David B. Bichara , Jason P. Gleghorn

Multi-relational learning on knowledge graphs infers high-order relations among the entities across the graphs. This learning task can be solved by label propagation on the tensor product of the knowledge graphs to learn the high-order…

Machine Learning · Computer Science 2020-05-19 Zhuliu Li , Raphael Petegrosso , Shaden Smith , David Sterling , George Karypis , Rui Kuang

Properties of molecules are indicative of their functions and thus are useful in many applications. With the advances of deep learning methods, computational approaches for predicting molecular properties are gaining increasing momentum.…

Quantitative Methods · Quantitative Biology 2021-07-07 Zhengyang Wang , Meng Liu , Youzhi Luo , Zhao Xu , Yaochen Xie , Limei Wang , Lei Cai , Qi Qi , Zhuoning Yuan , Tianbao Yang , Shuiwang Ji

Sequential labeling is a task predicting labels for each token in a sequence, such as Named Entity Recognition (NER). NER tasks aim to extract entities and predict their labels given a text, which is important in information extraction.…

Computation and Language · Computer Science 2024-06-06 Jianfeng He , Linlin Yu , Shuo Lei , Chang-Tien Lu , Feng Chen