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Towards understanding the fundamental limits of estimation from data of varied quality, we study the problem of estimating a mean parameter from heteroskedastic Gaussian observations where the variances are unknown and may vary arbitrarily…

Statistics Theory · Mathematics 2026-03-17 Yanjun Han , Abhishek Shetty , Jacob Shkrob

We propose a new prediction method for multivariate linear regression problems where the number of features is less than the sample size but the number of outcomes is extremely large. Many popular procedures, such as penalized regression…

Methodology · Statistics 2021-04-20 Yihe Wang , Sihai Dave Zhao

In many astrophysical settings covariance matrices of large datasets have to be determined empirically from a finite number of mock realisations. The resulting noise degrades inference and precludes it completely if there are fewer…

Instrumentation and Methods for Astrophysics · Physics 2017-01-11 Benjamin Joachimi

In this work, the estimation of the multivariate normal mean by different classes of shrinkage estimators is investigated. The risk associated with the balanced loss function is used to compare two estimators. We start by considering…

Statistics Theory · Mathematics 2021-07-30 Abdelkader Benkhaled , Mekki Terbeche , Abdenour Hamdaoui

In all areas of human knowledge, datasets are increasing in both size and complexity, creating the need for richer statistical models. This trend is also true for economic data, where high-dimensional and nonlinear/nonparametric inference…

Econometrics · Economics 2021-12-23 Dimitris Korobilis , Kenichi Shimizu

We consider unbiased estimation of a sparse nonrandom vector corrupted by additive white Gaussian noise. We show that while there are infinitely many unbiased estimators for this problem, none of them has uniformly minimum variance.…

Statistics Theory · Mathematics 2010-06-02 Alexander Jung , Zvika Ben-Haim , Franz Hlawatsch , Yonina C. Eldar

Purpose: To develop neural network (NN)-based quantitative MRI parameter estimators with minimal bias and a variance close to the Cram\'er-Rao bound. Theory and Methods: We generalize the mean squared error loss to control the bias and…

Medical Physics · Physics 2024-05-07 Andrew Mao , Sebastian Flassbeck , Jakob Assländer

We seek to improve estimates of the power spectrum covariance matrix from a limited number of simulations by employing a novel statistical technique known as shrinkage estimation. The shrinkage technique optimally combines an empirical…

Astrophysics · Physics 2009-11-13 Adrian C. Pope , István Szapudi

In linear regression we wish to estimate the optimum linear least squares predictor for a distribution over $d$-dimensional input points and real-valued responses, based on a small sample. Under standard random design analysis, where the…

Machine Learning · Statistics 2022-06-08 Michał Dereziński , Manfred K. Warmuth , Daniel Hsu

This paper considers the problem of estimating a high-dimensional vector of parameters $\boldsymbol{\theta} \in \mathbb{R}^n$ from a noisy observation. The noise vector is i.i.d. Gaussian with known variance. For a squared-error loss…

Information Theory · Computer Science 2018-03-19 K. Pavan Srinath , Ramji Venkataramanan

We consider the prediction of weak effects in a multiple-output regression setup, when covariates are expected to explain a small amount, less than $\approx 1%$, of the variance of the target variables. To facilitate the prediction of the…

In this article we provide some nonnegative and positive estimators of the mean squared errors(MSEs) for shrinkage estimators of multivariate normal means. Proposed estimators are shown to improve on the uniformly minimum variance unbiased…

Statistics Theory · Mathematics 2007-10-08 Hisayuki Hara

Motivated by the proliferation of observational datasets and the need to integrate non-randomized evidence with randomized controlled trials, causal inference researchers have recently proposed several new methodologies for combining biased…

Methodology · Statistics 2023-09-14 Evan T. R. Rosenman , Francesca Dominici , Luke Miratrix

For normal canonical models, and more generally a vast array of general spherically symmetric location-scale models with a residual vector, we consider estimating the (univariate) location parameter when it is lower bounded. We provide…

Statistics Theory · Mathematics 2012-07-24 Mohammad Jafari Jozani , Eric Marchand , William Strawderman

This article discusses estimation of a multivariate normal mean based on heteroscedastic observations. Under heteroscedasticity, estimators shrinking more on the coordinates with larger variances, seem desirable. Although they are not…

Statistics Theory · Mathematics 2022-06-23 Yuzo Maruyama , Lawrence D. Brown , Edward I. George

We propose a scalable variational Bayes method for statistical inference for a single or low-dimensional subset of the coordinates of a high-dimensional parameter in sparse linear regression. Our approach relies on assigning a mean-field…

Machine Learning · Statistics 2025-08-12 Ismaël Castillo , Alice L'Huillier , Kolyan Ray , Luke Travis

The widespread availability of high-dimensional biological data has made the simultaneous screening of many biological characteristics a central problem in computational biology and allied sciences. While the dimensionality of such datasets…

Methodology · Statistics 2023-03-10 Nima S. Hejazi , Philippe Boileau , Mark J. van der Laan , Alan E. Hubbard

We investigate Bayesian shrinkage methods for constructing predictive distributions. We consider the multivariate Normal model with a known covariance matrix and show that the Bayesian predictive density with respect to Stein's harmonic…

Statistics Theory · Mathematics 2017-07-31 Yuzo Maruyama , Toshio Ohnishi

The Bayes linear estimator is derived by minimizing the Bayes risk with respect to the squared loss function. Non-unbiased estimators such as ordinary ridge, typical shrinkage, fractional rank, and restricted least squares estimators, as…

Statistics Theory · Mathematics 2026-01-15 Hirai Mukasa

A variance reduction technique in nonparametric smoothing is proposed: at each point of estimation, form a linear combination of a preliminary estimator evaluated at nearby points with the coefficients specified so that the asymptotic bias…

Statistics Theory · Mathematics 2007-08-22 Ming-Yen Cheng , Liang Peng , Jyh-Shyang Wu