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Machine- and deep-learning approaches for biological sequences depend critically on transforming raw DNA, RNA, and protein FASTA files into informative numerical representations. However, this process is often fragmented across multiple…

Genomics · Quantitative Biology 2025-12-01 Hamid Ismail , Marwan Bikdash

With the development of next generation sequencing techniques, it is fast and cheap to determine protein sequences but relatively slow and expensive to extract useful information from protein sequences because of limitations of traditional…

Quantitative Methods · Quantitative Biology 2017-10-20 Renzhi Cao , Colton Freitas , Leong Chan , Miao Sun , Haiqing Jiang , Zhangxin Chen

Artificial intelligence (AI) techniques are widely applied in the life sciences. However, applying innovative AI techniques to understand and deconvolute biological complexity is hindered by the learning curve for life science scientists to…

Artificial Intelligence · Computer Science 2024-03-28 Nisha Pillai , Athish Ram Das , Moses Ayoola , Ganga Gireesan , Bindu Nanduri , Mahalingam Ramkumar

Under the impact of global climate changes and human activities, harmful algae blooms in surface waters have become a growing concern due to negative impacts on water related industries. Therefore, reliable and cost effective methods of…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Jason L. Deglint , Chao Jin , Alexander Wong

The main goal of this research is to produce a useful software for United Nations (UN), that could help to speed up the process of qualifying the UN documents following the Sustainable Development Goals (SDGs) in order to monitor the…

Information Retrieval · Computer Science 2021-09-14 Francesco Sovrano , Monica Palmirani , Fabio Vitali

In recent years, neural architecture-based recommender systems have achieved tremendous success, but they still fall short of expectation when dealing with highly sparse data. Self-supervised learning (SSL), as an emerging technique for…

Information Retrieval · Computer Science 2023-06-05 Junliang Yu , Hongzhi Yin , Xin Xia , Tong Chen , Jundong Li , Zi Huang

Motivation: The proliferation of Biomedical research articles has made the task of information retrieval more important than ever. Scientists and Researchers are having difficulty in finding articles that contain information relevant to…

Computation and Language · Computer Science 2020-11-04 Harsh Patel

Background: Single-cell RNA sequencing (scRNA-seq) yields valuable insights about gene expression and gives critical information about complex tissue cellular composition. In the analysis of single-cell RNA sequencing, the annotations of…

Genomics · Quantitative Biology 2023-03-29 Xiaowen Cao , Li Xing , Elham Majd , Hua He , Junhua Gu , Xuekui Zhang

Classification is an important task in many fields including biomedical research and machine learning. Traditionally, a classification rule is constructed based a bunch of labeled data. Recently, due to technological innovation and…

Methodology · Statistics 2014-06-19 Jing Wang , Eunsik Park , Yuan-chin Ivan Chang

Probabilistic programming frameworks are powerful tools for statistical modelling and inference. They are not immediately generalisable to phylogenetic problems due to the particular computational properties of the phylogenetic tree object.…

Populations and Evolution · Quantitative Biology 2022-11-11 Christiaan Swanepoel , Mathieu Fourment , Xiang Ji , Hassan Nasif , Marc A Suchard , Frederick A Matsen , Alexei Drummond

In this paper we will describe a new approach on the well-known suffix-array algorithm using Big Table Data Technology. We will demonstrate how it is possible to refactor a well-known algorithm coupled by taking advantage of an…

Databases · Computer Science 2020-03-26 Piero Giacomelli

RNA-sequencing (RNA-seq) has become an exemplar technology in modern biology and clinical applications over the past decade. It has gained immense popularity in the recent years driven by continuous efforts of the bioinformatics community…

Discovering patterns in data that best describe the differences between classes allows to hypothesize and reason about class-specific mechanisms. In molecular biology, for example, this bears promise of advancing the understanding of…

Machine Learning · Computer Science 2023-12-08 Nils Philipp Walter , Jonas Fischer , Jilles Vreeken

Semi-supervised Fine-Grained Recognition is a challenge task due to the difficulty of data imbalance, high inter-class similarity and domain mismatch. Recent years, this field has witnessed great progress and many methods has gained great…

Computer Vision and Pattern Recognition · Computer Science 2021-07-15 Hao Chang , Guochen Xie , Jun Yu , Qiang Ling

Neural Architecture Search (NAS) methods are widely used in various industries to obtain high quality taskspecific solutions with minimal human intervention. Event Sequences find widespread use in various industrial applications including…

We study the problem of optimizing biological sequences, e.g., proteins, DNA, and RNA, to maximize a black-box score function that is only evaluated in an offline dataset. We propose a novel solution, bootstrapped training of…

Quantitative Methods · Quantitative Biology 2024-03-26 Minsu Kim , Federico Berto , Sungsoo Ahn , Jinkyoo Park

Despite their high predictive accuracies, current machine learning systems often exhibit systematic biases stemming from annotation artifacts or insufficient support for certain classes in the dataset. Recent work proposes automatic methods…

Computation and Language · Computer Science 2024-10-30 Rakesh R. Menon , Shashank Srivastava

We present Searn, an algorithm for integrating search and learning to solve complex structured prediction problems such as those that occur in natural language, speech, computational biology, and vision. Searn is a meta-algorithm that…

Machine Learning · Computer Science 2009-07-07 Hal Daumé , John Langford , Daniel Marcu

The demand for text classification is growing significantly in web searching, data mining, web ranking, recommendation systems, and so many other fields of information and technology. This paper illustrates the text classification process…

Computation and Language · Computer Science 2025-09-03 Sadia Zaman Mishu , S M Rafiuddin

Educational resource understanding is vital to online learning platforms, which have demonstrated growing applications recently. However, researchers and developers always struggle with using existing general natural language toolkits or…

Computation and Language · Computer Science 2024-06-05 Zhenya Huang , Yuting Ning , Longhu Qin , Shiwei Tong , Shangzi Xue , Tong Xiao , Xin Lin , Jiayu Liu , Qi Liu , Enhong Chen , Shijing Wang
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