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A connection between the General Linear Model (GLM) in combination with classical statistical inference and the machine learning (MLE)-based inference is described in this paper. Firstly, the estimation of the GLM parameters is expressed as…

Machine Learning · Statistics 2022-02-10 Juan Manuel Gorriz , SIPBA group , John Suckling

High-dimensional longitudinal data is increasingly used in a wide range of scientific studies. To properly account for dependence between longitudinal observations, statistical methods for high-dimensional linear mixed models (LMMs) have…

Methodology · Statistics 2024-07-10 Anja Zgodic , Ray Bai , Jiajia Zhang , Peter Olejua , Alexander C. McLain

This paper proposes a desparsified GMM estimator for estimating high-dimensional regression models allowing for, but not requiring, many more endogenous regressors than observations. We provide finite sample upper bounds on the estimation…

Statistics Theory · Mathematics 2019-09-11 Mehmet Caner , Anders Bredahl Kock

We study the problem of detecting a change in the mean of one-dimensional Gaussian process data. This problem is investigated in the setting of increasing domain (customarily employed in time series analysis) and in the setting of fixed…

Statistics Theory · Mathematics 2017-04-11 Hossein Keshavarz , Clayton Scott , XuanLong Nguyen

Sampling the phase space of molecular systems -- and, more generally, of complex systems effectively modeled by stochastic differential equations -- is a crucial modeling step in many fields, from protein folding to materials discovery.…

Machine Learning · Computer Science 2023-12-12 Ellis R. Crabtree , Juan M. Bello-Rivas , Andrew L. Ferguson , Ioannis G. Kevrekidis

We propose a family of tests to assess the goodness-of-fit of a high-dimensional generalized linear model. Our framework is flexible and may be used to construct an omnibus test or directed against testing specific non-linearities and…

Methodology · Statistics 2019-11-14 Jana Janková , Rajen D. Shah , Peter Bühlmann , Richard J. Samworth

When the data are sparse, optimization of hyperparameters of the kernel in Gaussian process regression by the commonly used maximum likelihood estimation (MLE) criterion often leads to overfitting. We show that choosing hyperparameters (in…

Methodology · Statistics 2023-01-27 Sergei Manzhos , Manabu Ihara

We consider the problem of reconstructing a signal from multi-layered (possibly) non-linear measurements. Using non-rigorous but standard methods from statistical physics we present the Multi-Layer Approximate Message Passing (ML-AMP)…

Information Theory · Computer Science 2020-01-22 Andre Manoel , Florent Krzakala , Marc Mézard , Lenka Zdeborová

A common pursuit in modern statistical learning is to attain satisfactory generalization out of the source data distribution (OOD). In theory, the challenge remains unsolved even under the canonical setting of covariate shift for the linear…

Machine Learning · Statistics 2025-02-14 Yuanshi Liu , Haihan Zhang , Qian Chen , Cong Fang

Large Language Models (LLMs) have demonstrated inherent calibration capabilities, where predicted probabilities align well with correctness, despite prior findings that deep neural networks are often overconfident. Recent studies have…

Machine Learning · Computer Science 2025-11-04 Abhinav Joshi , Areeb Ahmad , Ashutosh Modi

Sparse regularized regression methods are now widely used in genome-wide association studies (GWAS) to address the multiple testing burden that limits discovery of potentially important predictors. Linear mixed models (LMMs) have become an…

Methodology · Statistics 2022-06-27 Julien St-Pierre , Karim Oualkacha , Sahir Rai Bhatnagar

There remains an open question about the usefulness and the interpretation of Machine learning (MLE) approaches for discrimination of spatial patterns of brain images between samples or activation states. In the last few decades, these…

Machine Learning · Statistics 2022-09-22 JM Gorriz , R. Martin-Clemente , C. G. Puntonet , A. Ortiz , J. Ramirez , J. Suckling

Multivariate linear mixed models (mvLMMs) have been widely used in many areas of genetics, and have attracted considerable recent interest in genome-wide association studies (GWASs). However, fitting mvLMMs is computationally non-trivial,…

Quantitative Methods · Quantitative Biology 2013-09-13 Xiang Zhou , Matthew Stephens

Generalized linear models (GLMs) have been used widely for modelling the mean response both for discrete and continuous random variables with an emphasis on categorical response. Recently Yang, Mandal and Majumdar (2013) considered full…

Statistics Theory · Mathematics 2013-05-06 Jie Yang , Abhyuday Mandal

Generative models provide a powerful framework for probabilistic reasoning. However, in many domains their use has been hampered by the practical difficulties of inference. This is particularly the case in computer vision, where models of…

Computer Vision and Pattern Recognition · Computer Science 2015-01-28 Varun Jampani , S. M. Ali Eslami , Daniel Tarlow , Pushmeet Kohli , John Winn

This paper considers the problem of networks reconstruction from heterogeneous data using a Gaussian Graphical Mixture Model (GGMM). It is well known that parameter estimation in this context is challenging due to large numbers of variables…

Machine Learning · Statistics 2013-10-08 Anani Lotsi , Ernst Wit

We study the generalized linear bandit (GLB) problem, a contextual multi-armed bandit framework that extends the classical linear model by incorporating a non-linear link function, thereby modeling a broad class of reward distributions such…

Machine Learning · Computer Science 2025-10-31 Yu-Jie Zhang , Sheng-An Xu , Peng Zhao , Masashi Sugiyama

After the inception of emotion recognition or affective computing, it has increasingly become an active research topic due to its broad applications. Over the past couple of decades, emotion recognition models have gradually migrated from…

Computation and Language · Computer Science 2023-08-23 Zixing Zhang , Liyizhe Peng , Tao Pang , Jing Han , Huan Zhao , Bjorn W. Schuller

A fundamental problem in modern supervised learning is computing reliable conditional prediction intervals in high-dimensional settings: existing methods often rely on restrictive modelling assumptions, do not scale as predictor dimension…

Machine Learning · Statistics 2026-02-24 Daniel Salnikov , Dan Leonte , Kevin Michalewicz

Identifying phase transitions and classifying phases of matter is central to understanding the properties and behavior of a broad range of material systems. In recent years, machine-learning (ML) techniques have been successfully applied to…

Disordered Systems and Neural Networks · Physics 2023-06-23 Julian Arnold , Frank Schäfer
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