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This paper studies the problem of statistical inference for genetic relatedness between binary traits based on individual-level genome-wide association data. Specifically, under the high-dimensional logistic regression models, we define…

Methodology · Statistics 2022-10-06 Rong Ma , Zijian Guo , T. Tony Cai , Hongzhe Li

The abundance of data affords researchers to pursue more powerful computational tools to learn the dynamics of complex system, such as neural networks, engineered systems and social networks. Traditional machine learning approaches capture…

Machine Learning · Computer Science 2024-05-16 Yan Shen , Fan Yang , Mingchen Gao , Wen Dong

This contribution is concerned with mathematical models for the dynamics of the genetic composition of populations evolving under recombination. Recombination is the genetic mechanism by which two parent individuals create the mixed type of…

Populations and Evolution · Quantitative Biology 2011-01-12 Ellen Baake

Despite the central role of sensor-derived measurements such as imaging traits and plasma biomarkers in biomedical research and clinical practice, existing generative models for disease prediction largely depend on event-level…

Artificial Intelligence · Computer Science 2026-05-12 Ziquan Wei , Tingting Dan , Guorong Wu

In genetic studies of complex diseases, the underlying mode of inheritance is often not known. Thus, the most powerful test or other optimal procedure for one model, e.g. recessive, may be quite inefficient if another model, e.g. dominant,…

Statistics Theory · Mathematics 2007-06-13 Gang Zheng , Boris Freidlin , Joseph L. Gastwirth

We introduce a stochastic household model for vector-borne diseases, in particular as relevant to prominent vectors belonging to the Aedes genus and hence the Zika, chikungunya, and dengue viruses. In this model, vectors remain local to…

Populations and Evolution · Quantitative Biology 2022-03-01 Andrew Black , Andrew Smith , Alun Lloyd , Joshua Ross

This paper deals with the problem of enforcing modular diagnosability for discrete-event systems that don't satisfy this property by their natural modularity. We introduce an approach to achieve this property combining existing modules into…

Systems and Control · Computer Science 2013-11-13 Dmitry Myadzelets , Andrea Paoli

Document-level Event Causality Identification (DECI) aims to identify causal relations between two events in documents. Recent research tends to use pre-trained language models to generate the event causal relations. Whereas, these methods…

Computation and Language · Computer Science 2024-03-19 Baiyan Zhang , Qin Chen , Jie Zhou , Jian Jin , Liang He

We describe convolutional deep exponential families (CDEFs) in this paper. CDEFs are built based on deep exponential families, deep probabilistic models that capture the hierarchical dependence between latent variables. CDEFs greatly reduce…

Machine Learning · Statistics 2021-10-29 Chengkuan Hong , Christian R. Shelton

We present DeepDECS, a new method for the synthesis of correct-by-construction discrete-event controllers for autonomous systems that use deep neural network (DNN) classifiers for the perception step of their decision-making processes.…

Biological living systems in general exhibit complex and diverse dynamics. The latter, in particular, is essential, since diversification increases the odds of survival of an organism while reducing the risk of extinction of the population.…

Probability · Mathematics 2022-08-19 Sandesh Athni Hiremath

It is well known that type-1 fuzzy sets (T1 FSs) have limited capabilities to handle some data uncertainties directly, and type-2 fuzzy sets (T2 FSs) can cover the shortcoming of T1 FSs to a certain extent. Fuzzy discrete event systems…

Systems and Control · Computer Science 2016-10-11 Weilin Deng , Daowen Qiu

Differentially private data releases are often required to satisfy a set of external constraints that reflect the legal, ethical, and logical mandates to which the data curator is obligated. The enforcement of constraints, when treated as…

Cryptography and Security · Computer Science 2020-08-25 Ruobin Gong , Xiao-Li Meng

We investigate the coordination and control problems of distributed discrete event systems that are composed of multiple subsystems subject to potential actuator and/or sensor faults. We model actuator faults as local controllability loss…

Systems and Control · Computer Science 2018-12-06 Jin Dai , Hai Lin

Civil registration vital statistics (CRVS) data are used to produce national estimates of maternal mortality, but are often subject to substantial reporting errors due to misclassification of maternal deaths. The accuracy of CRVS systems…

Applications · Statistics 2019-09-19 Emily Peterson , Doris Chou , Ann-Beth Moller , Alison Gemmill , Lale Say , Leontine Alkema

Discrete-event systems usually consist of discrete states and transitions between them caused by spontaneous occurrences of labelled (aka partially-observed) events. Due to the partially-observed feature, fundamental properties therein…

Systems and Control · Electrical Eng. & Systems 2021-11-24 Kuize Zhang

Although understanding and characterizing causal effects have become essential in observational studies, it is challenging when the confounders are high-dimensional. In this article, we develop a general framework $\textit{CausalEGM}$ for…

Machine Learning · Statistics 2023-03-20 Qiao Liu , Zhongren Chen , Wing Hung Wong

Developing and evaluating distributed inference algorithms remains difficult due to the lack of standardized tools for modeling heterogeneous devices and networks. Existing studies often rely on ad-hoc testbeds or proprietary…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-03-30 Doğaç Eldenk , Stephen Xia

Data-driven societal event forecasting methods exploit relevant historical information to predict future events. These methods rely on historical labeled data and cannot accurately predict events when data are limited or of poor quality.…

Machine Learning · Computer Science 2021-12-13 Songgaojun Deng , Huzefa Rangwala , Yue Ning

Complex social systems are composed of interconnected individuals whose interactions result in group behaviors. Optimal control of a real-world complex system has many applications, including road traffic management, epidemic prevention,…

Systems and Control · Computer Science 2019-05-08 Wen Dong , Bo Liu , Fan Yang