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This study proposes CGRclust, a novel combination of unsupervised twin contrastive clustering of Chaos Game Representations (CGR) of DNA sequences, with convolutional neural networks (CNNs). To the best of our knowledge, CGRclust is the…

Genomics · Quantitative Biology 2024-11-14 Fatemeh Alipour , Kathleen A. Hill , Lila Kari

Motivation: Modern genomics laboratories generate massive volumes of sequencing data, often resulting in significant storage costs. Genomics storage consists of duplicate files, temporary processing files, and redundant intermediate data.…

Genomics · Quantitative Biology 2025-11-27 Margot Celerie , Andrew Oldfield , William Ritchie

Rapid sequencing of individual human genome is prerequisite to genomic medicine, where diseases will be prevented by preemptive cures. Quantum-mechanical tunneling through single-stranded DNA in a solid-state nanopore has been proposed for…

As billions of personal data being shared through social media and network, the data privacy and security have drawn an increasing attention. Several attempts have been made to alleviate the leakage of identity information from face photos,…

Machine Learning · Computer Science 2021-08-17 Xiao Yang , Yinpeng Dong , Tianyu Pang , Hang Su , Jun Zhu , Yuefeng Chen , Hui Xue

Due to its hereditary nature, genomic data is not only linked to its owner but to that of close relatives as well. As a result, its sensitivity does not really degrade over time; in fact, the relevance of a genomic sequence is likely to be…

Cryptography and Security · Computer Science 2019-08-30 Bristena Oprisanu , Christophe Dessimoz , Emiliano De Cristofaro

The US Decennial Census provides valuable data for both research and policy purposes. Census data are subject to a variety of disclosure avoidance techniques prior to release in order to preserve respondent confidentiality. While many are…

Computers and Society · Computer Science 2025-10-02 Cynthia Dwork , Kristjan Greenewald , Manish Raghavan

DNA sequencing, especially of microbial genomes and metagenomes, has been at the core of recent research advances in large-scale comparative genomics. The data deluge has resulted in exponential growth in genomic datasets over the past…

Medical data is often highly sensitive in terms of data privacy and security concerns. Federated learning, one type of machine learning techniques, has been started to use for the improvement of the privacy and security of medical data. In…

Cryptography and Security · Computer Science 2022-04-19 Febrianti Wibawa , Ferhat Ozgur Catak , Salih Sarp , Murat Kuzlu , Umit Cali

Cloud-based enterprise search services (e.g., Amazon Kendra) are enchanting to big data owners by providing them with convenient search solutions over their enterprise big datasets. However, individuals and businesses that deal with…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-06-10 SM Zobaed , Mohsen Amini Salehi

Sharing genome data in a privacy-preserving way stands as a major bottleneck in front of the scientific progress promised by the big data era in genomics. A community-driven protocol named genomic data-sharing beacon protocol has been…

Cryptography and Security · Computer Science 2020-08-25 Kerem Ayoz , Erman Ayday , A. Ercument Cicek

To protect user privacy in data analysis, a state-of-the-art strategy is differential privacy in which scientific noise is injected into the real analysis output. The noise masks individual's sensitive information contained in the dataset.…

Cryptography and Security · Computer Science 2018-06-20 Xuan-Son Vu , Lili Jiang

Electronic information is increasingly often shared among entities without complete mutual trust. To address related security and privacy issues, a few cryptographic techniques have emerged that support privacy-preserving information…

Cryptography and Security · Computer Science 2013-09-23 Carlo Blundo , Emiliano De Cristofaro , Paolo Gasti

The issue of detecting deepfakes has garnered significant attention in the research community, with the goal of identifying facial manipulations for abuse prevention. Although recent studies have focused on developing generalized models…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Jiazhi Guan , Tianshu Hu , Hang Zhou , Zhizhi Guo , Lirui Deng , Chengbin Quan , Errui Ding , Youjian Zhao

Recent advances in synthetic data generation (SDG) have been hailed as a solution to the difficult problem of sharing sensitive data while protecting privacy. SDG aims to learn statistical properties of real data in order to generate…

Machine Learning · Computer Science 2024-05-10 Meenatchi Sundaram Muthu Selva Annamalai , Andrea Gadotti , Luc Rocher

Sequencing by Emergence (SEQE) is a new single-molecule nucleic acid (DNA/RNA) sequencing technology that estimates sequence as an emergent property of the binding and localization of a repertoire of short oligonucleotide probes. SEQE…

Genomics · Quantitative Biology 2021-08-04 Nicholas Boyd , Samuel Woodhouse , Kalim Mir

Genome-wide association studies (GWAS) are an essential tool in biomedical research for identifying genetic factors linked to health and disease. However, publicly releasing GWAS summary statistics poses well-recognized privacy risks,…

Quantitative Methods · Quantitative Biology 2025-12-05 Anupama Nandi , Seth Neel , Hyunghoon Cho

This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

Quantitative Methods · Quantitative Biology 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo

In an era where external data and computational capabilities far exceed statistical agencies' own resources and capabilities, they face the renewed challenge of protecting the confidentiality of underlying microdata when publishing…

Applications · Statistics 2022-12-29 John M Abowd , Michael B Hawes

With increasing frequency of high-profile privacy breaches in various online platforms, users are becoming more concerned about their privacy. And recommender system is the core component of online platforms for providing personalized…

Cryptography and Security · Computer Science 2024-01-31 Wentao Hu , Hui Fang

Differential privacy is known to protect against threats to validity incurred due to adaptive, or exploratory, data analysis -- even when the analyst adversarially searches for a statistical estimate that diverges from the true value of the…

Cryptography and Security · Computer Science 2022-07-25 Elbert Du , Cynthia Dwork
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