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The mechanisms of photon propagation in random media in the diffusive multiple scattering regime have been previously studied using diffusion approximation. However, similar understanding in the low-order (sub-diffusion) scattering regime…

Mesoscale and Nanoscale Physics · Physics 2007-05-23 Hariharan Subramanian , Prabhakar Pradhan , Young Kim , Vadim Backman

Wavefront shaping enables targeted delivery of coherent light into random-scattering media, such as biological tissue, by constructive interference of scattered waves. However, broadband waves have short coherence times, weakening the…

Three-photon (3P) microscopy is getting traction due to its superior performance in deep tissues. Yet, aberrations and light scattering still pose one of the main limitations in the attainable depth ranges for high-resolution imaging. Here,…

Recent advances in propagation-based phase-contrast imaging, such as hierarchical imaging, have enabled the visualization of internal structures in large biological specimens and material samples. However, modulation-based techniques, which…

Non-invasive detection of objects embedded inside an optically scattering medium is essential for numerous applications in engineering and sciences. However, in most applications light at visible or near-infrared wavebands is scattered by…

Inhomogeneities in the refractive index of a biological sample can introduce phase aberrationsin microscopy systems, severely impairing the quality of images. Adaptive optics can be employed to correct for phase aberrations and improve…

We present an algorithm to estimate fast and accurate depth maps from light fields via a sparse set of depth edges and gradients. Our proposed approach is based around the idea that true depth edges are more sensitive than texture edges to…

Computer Vision and Pattern Recognition · Computer Science 2021-07-08 Numair Khan , Min H. Kim , James Tompkin

The penetration depth of photoacoustic imaging in biological tissues has been fundamentally limited by the strong optical attenuation when light is delivered externally through the tissue surface. To address this issue, we previously…

Medical Physics · Physics 2021-02-24 Mucong Li , Tri Vu , Georgy Sankii , Brenton Winship , Kohldon Boydston , Russell Terry , Pei Zhong , Junjie Yao

By applying the properties of Fabry-Perot resonance and Rayleigh anomaly, we have shown that a photonic crystal slab can scatter the light from an incident plane wave into a diffracted light with a very large reflection or transmission…

Optics · Physics 2017-03-23 Kokou B. Dossou

Aberrations limit scanning fluorescence microscopy when imaging in scattering materials such as biological tissue. Model-based approaches for adaptive optics take advantage of a computational model of the optical setup. Such models can be…

Optics · Physics 2021-07-07 Ivan Vishniakou , Johannes D. Seelig

Achieving fast, large-scale volumetric imaging with micrometer resolution has been a persistent challenge in the field of biological microscopy. To address this challenge, we report an augmented version of light field microscopy,…

Optics · Physics 2024-10-11 Aymerick Bazin , Amaury Badon

Optical-resolution fluorescence imaging through and within complex samples presents a significant challenge due to random light scattering, with substantial implications across multiple fields. While significant advancements in coherent…

Optics · Physics 2023-12-27 Gil Weinberg , Elad Sunray , Ori Katz

In optical imaging, light propagation is affected by the inhomogeneities of the medium. Sample-induced aberrations and multiple scattering can strongly degrade the image resolution and contrast. Based on a dynamic correction of the incident…

Due to the highly inhomogeneous distributions of refractive indexes, light propagation in complex media such as biological tissue experiences multiple light scattering events. The suppression and control of multiple light scattering events…

Recently an optical amplification process called the plasmon injection scheme was introduced as an effective solution to overcoming losses in metamaterials. Implementations with near-field imaging applications have indicated substantial…

Optics · Physics 2020-08-26 Anindya Ghoshroy , Wyatt Adams , Durdu O. Guney

Light-sheet microscopes must compromise between field of view, optical sectioning, resolution, and detection efficiency. High-numerical-aperture (NA) detection objective lenses provide high resolution but their narrow depth of field fails…

Imaging through opaque, highly scattering walls is a long sought after capability with potential applications in a variety of fields. The use of wavefront shaping to compensate for scattering has brought a renewed interest as a potential…

An ideal imaging system provides a spatial resolution that is ultimately dictated by the numerical aperture (NA) of the illumination and collection optics. In biological tissue, resolution is further affected by scattering limiting the…

Aberrations limit optical systems in many situations, for example when imaging in biological tissue. Machine learning offers novel ways to improve imaging under such conditions by learning inverse models of aberrations. Learning requires…

Optics · Physics 2021-04-30 Ivan Vishniakou , Johannes D. Seelig

The resonant absorption of light by an ensemble of absorbers decreases when the resonance is inhomogeneously broadened, as only a fraction of the ensemble contributes to the absorption at any given optical frequency. Recovering the lost…

Quantum Physics · Physics 2019-11-22 Ohr Lahad , Ran Finkelstein , Omri Davidson , Ohad Michel , Eilon Poem , Ofer Firstenberg