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Digital microfluidic (DMF) biochips are now being extensively used to automate several biochemical laboratory protocols such as clinical analysis, point-of-care diagnostics, and polymerase chain reaction (PCR). In many biological assays,…
We present a novel method for real-time monitoring and kinetic analysis of fluorescence in situ hybridization (FISH). We implement the method using a vertical microfluidic probe containing a microstructure designed for rapid switching…
Quality control in molecular optical sectioning microscopy is indispensable for transforming acquired digital images from qualitative descriptions to quantitative data. Although numerous tools, metrics, and phantoms have been developed,…
High-Q optical resonators allow label-free detection of individual nanoparticles through perturbation of optical signatures but have practical limitations due to reliance on random diffusion to deliver particles to the sensing region. We…
Biocompatible microencapsulation is of widespread interest for the targeted delivery of active species in fields such as pharmaceuticals, cosmetics and agro-chemistry. Capsules obtained by the self-assembly of polymers at interfaces enable…
The detection and classification of microplastics in water remain a significant challenge due to their diverse properties and the limitations of traditional optical methods. Standard spectroscopic techniques often suffer from the strong…
Accurate water level sensing is essential for flood monitoring, agricultural irrigation, and water resource optimization. Traditional methods require dedicated sensor deployments, leading to high installation costs, vulnerability to…
Accurate pressure measurements in micrometric channels are essential for a wide range of microfluidic applications. Existing approaches rely on a variety of sensing mechanisms, but generally require the integration of additional probes or…
We present a theoretical model for the evolution of mixture concentrations in a micro-pervaporation device, similar to those recently presented experimentally. The described device makes use of the pervaporation of water through a thin PDMS…
We describe a technique of image analysis providing the time resolved shape of a water surface simultaneously with the three-component velocity field on this surface. The method relies on a combination of stereoscopic surface mapping and…
A laboratory set-up has been developed to more precisely measure the DOM optical sensitivity as a function of angle and wavelength. DOMs are calibrated in water using a broad beam of light whose intensity is measured with a NIST calibrated…
The global need for clean water requires sustainable technology for purifying contaminated water. Highly efficient solar-driven photodegradation is a sustainable strategy for wastewater treatment. In this work, we demonstrate that the…
In this study we present an interferometric technique based on multiple wavelengths to capture the transient free surface contour of nanoliter drops spreading on a wettable surface, in particular close to the three-phase contact line.…
To cope with the challenging environment of the planned high luminosity upgrade of the Large Hadron Collider (HL-LHC), scheduled to start operation in 2029, CMS will replace its entire tracking system. The requirements for the tracker are…
The accurate measurement of complex liquid permittivity in a frequency range provides important information on liquid properties in comparison to single frequency permittivity investigations. The multifrequency microwave characterization…
Size and shape are critical discriminators between molecular species and states. We describe a micro-chip based high-throughput imaging approach offering rapid and precise determination of molecular properties under native solution…
Effective spatio-temporal measurements of water surface elevation (water waves) in laboratory experiments are essential for scientific and engineering research. Existing techniques are often cumbersome, computationally heavy and generally…
An instrument has been developed for precision controlled exposures of electronic devices and material samples in particle beams. The instrument provides simultaneously a real time record of the profile of the beam and the fluence received.…
Three-dimensional (3D) biomedical image sets are often acquired with in-plane pixel spacings that are far less than the out-of-plane spacings between images. The resultant anisotropy, which can be detrimental in many applications, can be…
We characterize the electro-phoretic motion of charged sphere suspensions in the presence of substantial electro-osmotic flow using a recently introduced small angle super-heterodyne dynamic light scattering instrument (ISASH-LDV).…