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Efficient molecular dynamics (MD) simulation is vital for understanding atomic-scale processes in materials science and biophysics. Traditional density functional theory (DFT) methods are computationally expensive, which limits the…

Machine Learning · Computer Science 2025-10-03 Hung Le , Sherif Abbas , Minh Hoang Nguyen , Van Dai Do , Huu Hiep Nguyen , Dung Nguyen

Domain-Specific Languages (DSLs) improve programmers productivity by decoupling problem descriptions from algorithmic implementations. However, DSLs for High-Performance Computing (HPC) have two additional critical requirements: performance…

Mathematical Software · Computer Science 2022-04-28 Sandra Macià , Pedro J. Martıínez-Ferrer , Eduard Ayguadé , Vicenç Beltran

Most atomistic machine learning (ML) models rely on a locality ansatz, and decompose the energy into a sum of short-ranged, atom-centered contributions. This leads to clear limitations when trying to describe problems that are dominated by…

We have extended the multilevel summation (MLS) method, originally developed to evaluate long-range Coulombic interactions in molecular dynamics (MD) simulations [Skeel et al., J. Comput. Chem., 23, 673 (2002)], to handle dispersion…

Materials Science · Physics 2014-01-16 Daniel Tameling , Paul Springer , Paolo Bientinesi , Ahmed E. Ismail

Coulomb interaction, following an inverse-square force-law, quantifies the amount of force between two stationary and electrically charged particles. The long-range nature of Coulomb interactions poses a major challenge to molecular…

Computational Physics · Physics 2022-01-26 Jiuyang Liang , Pan Tan , Yue Zhao , Lei Li , Shi Jin , Liang Hong , Zhenli Xu

Ferroelectric materials with switchable spontaneous polarization underpin non-volatile memories, transistors, sensors, and emerging neuromorphic chips. Their performance and stability are governed by polarization dynamics and domain…

Materials Science · Physics 2026-03-20 Dongyu Bai , Ri He , Junxian Liu , Liangzhi Kou

This article introduces a highly parallel algorithm for molecular dynamics simulations with short-range forces on single node multi- and many-core systems. The algorithm is designed to achieve high parallel speedups for strongly…

Computational Physics · Physics 2013-11-20 R. Meyer

We provided a concise and self-contained introduction to molecular dynamics (MD) simulation, which involves a body of fundamentals needed for all MD users. The associated computer code, simulating a gas of classical particles interacting…

Materials Science · Physics 2021-04-01 Ashkan Shekaari , Mahmoud Jafari

A proper treatment of electrostatic interactions is crucial for the accurate calculation of forces in computer simulations. Electrostatic interactions are typically modeled using Ewald based methods, which have become one of the…

Soft Condensed Matter · Physics 2016-09-21 K. A. Terrón-Mejía , R. López-Rendón , A. Gama Goicochea

The molecular dynamics simulation code ls1 mardyn is presented. It is a highly scalable code, optimized for massively parallel execution on supercomputing architectures, and currently holds the world record for the largest molecular…

With recent advancements in machine learning for interatomic potentials, Python has become the go-to programming language for exploring new ideas. While machine-learning potentials are often developed in Python-based frameworks, existing…

The evaluation of long-range Coulomb interactions is a significant cost in molecular dynamics (MD), even when using Particle Mesh Ewald (PME) or Particle-Particle-Particle-Mesh (PPPM) methods, which rely on Ewald splitting and the fast…

Numerical Analysis · Mathematics 2026-04-21 Jiuyang Liang , Libin Lu , Alex Barnett , Leslie Greengard , Shidong Jiang

An efficient representation of observed data has many benefits in various domains of engineering and science. Representing static data sets, such as images, is a living branch in machine learning and eases downstream tasks, such as…

Systems and Control · Computer Science 2018-09-28 Friedrich Solowjow , Arash Mehrjou , Bernhard Schölkopf , Sebastian Trimpe

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková

Molecular dynamics (MD) simulations play a crucial role in resolving the underlying conformational dynamics of molecular systems. However, their capability to correctly reproduce and predict dynamics in agreement with experiments is limited…

Chemical Physics · Physics 2025-05-19 Ivan Gilardoni , Valerio Piomponi , Thorben Fröhlking , Giovanni Bussi

We present the basic idea, implementation, measured performance and performance model of FDPS (Framework for developing particle simulators). FDPS is an application-development framework which helps the researchers to develop particle-based…

Instrumentation and Methods for Astrophysics · Physics 2016-06-15 Masaki Iwasawa , Ataru Tanikawa , Natsuki Hosono , Keigo Nitadori , Takayuki Muranushi , Junichiro Makino

Nonlocal models, including peridynamics, often use integral operators that embed lengthscales in their definition. However, the integrands in these operators are difficult to define from the data that are typically available for a given…

Materials Science · Physics 2022-01-05 Huaiqian You , Yue Yu , Stewart Silling , Marta D'Elia

We present a fast and accurate method to calculate the electrostatic energy and forces of interacting particles with the boundary conditions appropriate to surfaces, i.e periodic in the two directions parallel to the surface and free in the…

Computational Physics · Physics 2009-11-13 S. Alireza Ghasemi , Alexey Neelov , Stefan Goedecker

There is a growing demand to deploy computation-intensive deep learning (DL) models on resource-constrained mobile devices for real-time intelligent applications. Equipped with a variety of processing units such as CPUs, GPUs, and NPUs, the…

Machine Learning · Computer Science 2024-05-06 Sicong Liu , Wentao Zhou , Zimu Zhou , Bin Guo , Minfan Wang , Cheng Fang , Zheng Lin , Zhiwen Yu

The combination of machine learning and physical laws has shown immense potential for solving scientific problems driven by partial differential equations (PDEs) with the promise of fast inference, zero-shot generalisation, and the ability…

Machine Learning · Computer Science 2024-09-11 Nacime Bouziani , David A. Ham , Ado Farsi